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Neuronal autophagy and neurodegenerative diseases

Son JH, Shim JH, Kim KH, Ha JY, Han JY

Autophagy is a dynamic cellular pathway involved in the turnover of proteins, protein complexes, and organelles through lysosomal degradation. The integrity of postmitotic neurons is heavily dependent on high basal...
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Why is autophagy important in human diseases?

Jing K, Lim K

The process of macroautophagy (referred to hereafter as autophagy), is generally characterized by the prominent formation of autophagic vesicles in the cytoplasm. In the past decades, studies of autophagy have...
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A Case of Adult Polyglucosan Body Disease

Lee SY, Park JH, Kim SH, Kim TS, Kim WJ, Choi YC

Adult polyglucosan body disease (APBD) is a rare neurological disease, characterized by adult onset (fifth to seventh decades), progressive sensorimotor or pure motor peripheral neuropathy, upper motor neuron symptoms, neurogenic...
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