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Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors

Chen L, Endler A, Shibasaki

The mechanisms that regulate angiogenesis in hypoxia or hypoxic microenvironment are modulated by several pro- and antiangiogenic factors. Hypoxia-inducible factors (HIFs) have been established as the basic and major inducers...
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Ongoing angiogenesis in blood vessels of the abdominal aortic aneurysm

Paik DC, Fu C, Bhattacharya J, David Tilson M

  • KMID: 1103319
  • Exp Mol Med.
  • 2004 Dec;36(6):524-533.
Pathogenesis of the abdominal aortic aneurysm has been attributed to neovascularization of the aortic wall. However, it is not clear whether angiogenesis persists in the aneurysm. In sections of aneurysms,...
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