- Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines
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Shin SO, Lee KH, Kim JH, Baek SH, Park JW, Gabrielson EW, Kwon TK
- KMID: 755098
- Exp Mol Med.
- 2000 Dec;32(4):193-196.
Centrosomes maintain genomic stability by establishing the bipolar spindles during cell division and, execute accurate segregation of chromosomes during mitosis. In this study, we have demonstrated that there... -
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- Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells
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Hwang WC, Kim MK, Song JH, Choi KY, Min DS
- KMID: 2155389
- Exp Mol Med.
- 2014 Dec;46(12):e124.
- doi: 10.1038/emm.2014.74
Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase... -
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- A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-beta1-induced MMP-1 and MMP-9 expression in breast cancer cells
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Kim S, Han J, Shin I, Kil WH, Lee JE, Nam SJ
- KMID: 1387358
- Exp Mol Med.
- 2012 Aug;44(8):473-482.
Overexpression of HER2 correlates with more aggressive tumors and increased resistance to cancer chemotherapy. However, a functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on tumor metastasis has not... -
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- Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells
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Lim HW, Hong S, Jin W, Lim S, Kim SJ, Kang HJ, Park EH, Ahn K, Lim CJ
- KMID: 1089461
- Exp Mol Med.
- 2005 Oct;37(5):497-506.
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in... -
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- Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells
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Chin C, Bae JH, Kim MJ, Hwang JY, Kim SJ, Yoon MS, Lee MK, Kim DW, Chung BS, Kang CD, Kim SH
- KMID: 1116206
- Exp Mol Med.
- 2005 Dec;37(6):608-618.
Here we determined which radiation-responsive genes were altered in radioresistant CEM/IR and FM3A/IR variants, which showed higher resistance to irradiation than parental human leukemia CEM and mouse mammary carcinoma FM3A... -
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- Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women
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Lee SA, Kang D, Nishio H, Lee MJ, Kim DH, Han W, Yoo KY, Ahn SH, Choe KJ, Hirvonen A, Noh DY
- KMID: 1380205
- Exp Mol Med.
- 2004 Apr;36(2):116-121.
To evaluate the interactive effect of methylenetetrahydrofolate reductase (MTHFR) genotype and dietary factors on the development of breast cancer, a hospital based case-control study was conducted in South Korean study... -
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