- Cytotoxic Neoflavonoids and Chalcones from the Heartwood of Dalbergia melanoxylon
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Chung HS
- KMID: 2534103
- Nat Prod Sci.
- 2022 Sep;28(3):115-120.
- doi: 10.20307/nps.2022.28.3.115
Ten compounds, consisting of neoflavonoids (1-5), isoflavonoids (6 and 7), flavanone (8), and chalcones (9 and 10) were isolated from the ethyl acetate and n-butanol-soluble fractions of the heartwood of... -
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- Evaluation of the Antidiabetic, Islet Protective and Beta-Cell Regenerative Effects of Tinospora crispa (L.)
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Yusof N, Goh MPY, Ahmad N
- KMID: 2534101
- Nat Prod Sci.
- 2022 Sep;28(3):105-114.
- doi: 10.20307/nps.2022.28.3.105
Tinospora crispa (L.) is a medicinal plant traditionally used to treat various ailments including diabetes. The stem has been widely studied for its antidiabetic properties, however the antidiabetic potential of... -
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- Inhibitory Effects of Forsythia velutina and its Chemical Constituents on LPS-induced Nitric Oxide Production in BV2 Microglial Cells
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Kim NY, Ko MS, Lee CH, Lee TJ, Hwang KW, Park SY
- KMID: 2534114
- Nat Prod Sci.
- 2022 Sep;28(3):153-160.
- doi: 10.20307/nps.2022.28.3.153
Neuroinflammation is known to be associated with brain injury in Alzheimer’s disease (AD), and the inhibition of microglial activation, a key player in inflammatory response, is considerd as important target... -
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- Bioprospecting of Endophytic Fungi as Promising Anti-MRSA Agents
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Wei YM, Tan JS, Tang HW, Tong WY, Leong CR, Tan WN
- KMID: 2534098
- Nat Prod Sci.
- 2022 Sep;28(3):93-104.
- doi: 10.20307/nps.2022.28.3.93
Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to the global healthcare system. Ineffective and resistance to antibiotic treatments have increased morbidity and mortality rates worldwide. New and effective antibiotics are... -
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- Phytochemical Characterization of Vitex negundo Leaves: a Potent Antiandrogenic and Antioxidant Agent
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Sharath J, Shahin Taj RA, Bhagya M
- KMID: 2534106
- Nat Prod Sci.
- 2022 Sep;28(3):130-137.
- doi: 10.20307/nps.2022.28.3.130
This study was conducted to characterise phytochemicals and to explore the biological activities of Vitex negundo leaves. The washed, course powder of V. negundo leaves were extracted with different solvents... -
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- Tryptophan-derived Alkaloids from Hedera rhombea Fruits and Their Butyrylcholinesterase Inhibitory Activity
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Ha MT, Park SE, Kim JA, Woo MH, Choi JS, Min BS
- KMID: 2534110
- Nat Prod Sci.
- 2022 Sep;28(3):138-142.
- doi: 10.20307/nps.2022.28.3.138
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease in industrialized countries. It is estimated that about 47 million people living with dementia and the number of cases will... -
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- Evaluation of Anti-cancer and Anti-proliferative Activity of Medicinal Plant Extracts (Saffron, Green Tea, Clove, Fenugreek) on Toll Like Receptors Pathway
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Ajmal S, Shafqat M, Ajmal L, Younas H, Tasadduq R, Mahmood N
- KMID: 2534104
- Nat Prod Sci.
- 2022 Sep;28(3):121-129.
- doi: 10.20307/nps.2022.28.3.121
Despite considerable efforts, cancer remains an aggressive killer worldwide. Chemotherapeutic drugs that are currently in use lead to destructive side effects and have not succeeded in fulfilling expectations. For centuries,... -
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- α-Glucosidase Inhibitory Activity of Phenolic Compounds Isolated from the Stems of Caesalpinia decapetala var. japonica
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Le TT, Ha MT, Hoang LM, Vu NK, Kim JA, Min BS
- KMID: 2534113
- Nat Prod Sci.
- 2022 Sep;28(3):143-152.
- doi: 10.20307/nps.2022.28.3.143
In our study, sixteen known phenolic compounds, including quercetin (1), methyl gallate (2), caesalpiniaphenol C (3), 8S,8′S,7′R-(‒)-lyoniresinol (4), 7,3′,5′-trihydroxyflavanone (5), sappanchalcone (6), sappanone A (7), taxifolin (8), fisetin (9), fustin... -
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