- Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake
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Yang HX, Shang Y, Jin Q, Wu YL, Liu J, Qiao CY, Zhan ZY, Ye H, Nan JX, Lian LH
- KMID: 2503471
- Biomol Ther.
- 2020 Jul;28(4):320-327.
- doi: 10.4062/biomolther.2020.008
In current study, we aimed to investigate whether the gentiopicroside (GPS) derived from Gentiana manshurica Kitagawa could block the progression of alcoholic hepatic steatosis to fibrosis induced by chronic ethanol... -
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- Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation
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Dou JY, Jiang YC, Hu ZH, Yao KC, Yuan MH, Bao XX, Zhou MJ, Liu Y, Li ZX, Lian LH, Nan JX, Wu YL
- KMID: 2529890
- Biomol Ther.
- 2022 May;30(3):246-256.
- doi: 10.4062/biomolther.2021.136
The present study focused on the potential mechanism of betulin (BT), a pentacyclic triterpenoid isolated from the bark of white birch (Betula pubescens), against chronic alcohol-induced lipid accumulation and metaflammation.... -
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