Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

38 results
Display

Asp 280 residue is important in the activity of the Escherichia coli leader peptidase

Sung MS, Park KS

  • KMID: 1029933
  • Exp Mol Med.
  • 1999 Jun;31(2):64-69.
Leader peptidase is a novel serine protease in Escherichia coli, which catalyzes the cleavage of amino-terminal signal sequences from exported proteins. It is an integral membrane protein containing two transmembrane segments with...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor

Rhee MH

  • KMID: 1095120
  • J Vet Sci.
  • 2002 Sep;3(3):185-191.
Using site-directed mutagenesis technique, I have replaced serine 285 and serine 292 with the alanine, and assessed the binding of agonist and signaling such as the inhibition of adenylyl cyclase...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix

Lee EH, Allen PD

  • KMID: 1090962
  • Exp Mol Med.
  • 2007 Oct;39(5):594-602.
To investigate the mechanism by which the C-terminus (4,938-5,037) of the ryanodine receptor 1 (RyR1) homo-tetramerizes, forming a functional Ca2+ -release channel, the structural requirements for the tetramerization were studied...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression and Characterization of the Human Immunodeficiency Virus Type 1 Mutant Envelope Glycoproteins in Mammalian Cells

Ryu JY, Park JS

  • KMID: 1544250
  • J Korean Soc Virol.
  • 1999 Sep;29(3):183-193.
Human immunodeficiency virus type 1(HIV-1) envelope glycoprotein is synthesized as a 160KDa precursor, gp160, that is cleaved by a cellular protease to form the gp120 and gp41 subunits. Mammalian expression...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Site-Specific Mutagenesis in Human Cells by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives

Moon KY

  • KMID: 2127916
  • Cancer Res Treat.
  • 2004 Apr;36(2):151-156.
PURPOSE: 7-Bromomethylbenz[a]anthracene is a well- known mutagen and carcinogen. The aim of this study is to determine the mutagenic potency of its two major DNA adducts [N2-(benz[a]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[a]a2G) and N6-(benz[a]anthracen-7-...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Intrinsic Gating in Inward Rectifier Potassium Channels (Kir2.1) with Low Polyamine Affinity Generated by Site Directed Mutagenesis

So I, Ashmole I, Soh H, Park C, Spencer P, Leyland M, Stanfield

  • KMID: 2071587
  • Korean J Physiol Pharmacol.
  • 2003 Jun;7(3):131-142.
We have studied mutant forms of Kir2.1 in which an aspartate residue (D172), important for gating by intracellular polyamines, is replaced by one of three basic residues (Arg, Lys or...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Ahcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association

Park PW, Ahn JY, Yang D

Inositol-1,4,5-triphosphate [IP3] receptors binding protein released with IP3 (IRBIT) was previously reported as an activator of NBCe1-B. Recent studies have characterized IRBIT homologue S-Adenosylhomocysteine hydrolase-like 2 (AHCYL2). AHCYL2 is highly...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B

Lee KP, Kim HJ, Yang D

Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and binds to PP1-binding consensus residues (FxxR/KxR/K) in NBCe1-B....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids

Moon KY

  • KMID: 1807225
  • Cancer Res Treat.
  • 2003 Feb;35(1):75-80.
PURPOSE: 7-Bromomethylbenz[alpha]anthracene is a known mutagen and carcinogen. The mutagenic potency of its two major DNA adducts, i.e., N2-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[alpha]a2G) and N6-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyadenosine (b[alpha]a6A), as well as the simpler benzylated analogs,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Search for "Proximal Histidine" of Thyroperoxidase Using Site Directed Mutagenesis

Kim WB, Shong YK

  • KMID: 2200381
  • J Korean Soc Endocrinol.
  • 2003 Aug;18(4):371-378.
BACKGROUND: Thyroperoxidase (TPO), a transmembrane heme containing glycoprotein, catalyzes iodide organification and thyroid hormone synthesis. It is a single peptide making a loop with more than one disulfide bond. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding

Lee Y, Kim H, Chung J

The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Volatile General Anesthetics and Tandem Pore Domain K+ Channel

Shin WJ

  • KMID: 1482465
  • Hanyang Med Rev.
  • 2008 Nov;28(4):63-72.
Two-pore domain K+ (K2P) channels are recently described. They have properties of background K+ channels, and play a crucial role in setting the resting membrane potential and regulating cell excitability....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Autoantigenic Role of Variant Thyroperoxidase

Shong YK, Moon DH, Kim GS

  • KMID: 2461605
  • J Korean Soc Endocrinol.
  • 1996 Mar;11(1):61-67.
Background: Thyroperoxidase(TPO) is one of the most important autoantigens in autoimmune thyroid disorders and autoantibody to TPO is found in almost every patients with various autoimmune thyroid diseases. Human TPO...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

Im SS, Kim JW, Kim TH, Song XL, Kim SY, Kim HI, Ahn YH

  • KMID: 755748
  • Exp Mol Med.
  • 2005 Apr;37(2):101-110.
In the present study, we show that the expression of type 2 glucose transporter isoform (GLUT2) could be regulated by PPAR-gamma in the liver. Rosiglitazone, PPAR-gamma agonist, activated the GLUT2...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
IL-33 promotes IL-10 production in macrophages: a role for IL-33 in macrophage foam cell formation

Zhang HF, Wu MX, Lin YQ, Xie SL, Huang TC, Liu PM, Nie RQ, Meng QQ, Luo NS, Chen YX, Wang JF

We evaluated the role of IL-10- in IL-33-mediated cholesterol reduction in macrophage-derived foam cells (MFCs) and the mechanism by which IL-33 upregulates IL-10. Serum IL-33 and IL-10 levels in coronary...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Binding Properties of Glycosylated and Non-Glycosylated Tim-3 Molecules on CD4+CD25+ T Cells

Lee MJ, Heo YM, Hong SH, Kim K, Park S

BACKGROUND: T cell immunoglobulin and mucin domain containing 3 protein (Tim-3) expressed on terminally differentiated Th1 cells plays a suppressive role in Th1-mediated immune responses. Recently, it has been shown...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Safety and immunogenicity of recombinant rabies virus (ERAGS) in mice and raccoon dogs

Yang DK, Kim HH, Choi SS, Kim JT, Lee KB, Lee SH, Cho IS

PURPOSE: The development of a genetically modified live rabies vaccine applicable to wild raccoon dogs is necessary for the eradication of rabies in Korea. Thus, we constructed a recombinant rabies...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress

Heo JI, Lee MS, Kim JH, Lee JS, Kim J, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 1094155
  • Exp Mol Med.
  • 2006 Jun;38(3):295-301.
The inducible 70 kDa heat shock proteins (Hsp70) in mice are encoded by two almost identical genes, hsp70.1 and hsp70.3. Studies have found that only hsp70.1 is induced by hypertonic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Development of two novel nontoxic mutants of Escherichia coli heat-labile enterotoxin

Park EJ, Chang JH, Kim JS, Chung SI, Yum JS

  • KMID: 1029939
  • Exp Mol Med.
  • 1999 Jun;31(2):101-107.
Escherichia coli heat-labile enterotoxin (LT) is composed of catalytic A and non-catalytic homo-pentameric B subunits and causes diarrheal disease in human and animals. In order to produce a nontoxic LT for vaccine...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Translational Read-Through of a Nonsense Mutation Causing Bartter Syndrome

Cho HY, Lee BH, Cheong HI

Bartter syndrome (BS) is classified into 5 genotypes according to underlying mutant genes and BS III is caused by loss-of-function mutations in the CLCNKB gene encoding for basolateral ClC-Kb. BS...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr