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Conformation-specific Antibodies Targeting Aggregated Forms of α-synuclein Block the Propagation of Synucleinopathy

Choi M, Kim Tk, Ahn J, Lee JS, Jung BC, An S, Kim D, Lee MJ, Mook-Jung I, Lee SH, Lee SJ

Abnormal aggregation of α-synuclein is a key element in the pathogenesis of several neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. α-synuclein aggregation spreads...
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