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Cost-Effectiveness of Age-Expanding Strategy of Latent Tuberculosis Infection Treatment in Household Contacts in South Korea

Cho H, Seok J, Park Y, Kim HJ, Lee EH, Park J, Park DA, Kang YA, Lee J

Purpose: The strategy of latent tuberculosis infection (LTBI) treatment in household tuberculosis (TB) contacts has been expanding in South Korea. However, there is little evidence of the cost-effectiveness of LTBI...
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A Neuroprotective Action of Quercetin and Apigenin through Inhibiting Aggregation of Aβ and Activation of TRKB Signaling in a Cellular Experiment

Chiu YJ, Teng YS, Chen CM, Sun YC, Hsieh-Li HM, Chang KH, Lee-Chen GJ

Alzheimer’s disease (AD) is a neurodegenerative disease with progressive memory loss and the cognitive decline. AD is mainly caused by abnormal accumulation of misfolded amyloid β (Aβ), which leads to...
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Electroencephalography source localization

Eom TH

Electroencephalography (EEG) has been and is still widely used in brain function research. EEG has advantages over other neuroimaging modalities. First, it not only directly images the electrical activity of...
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Predicting Pathological Complete Response in Breast Cancer After Two Cycles of Neoadjuvant Chemotherapy by Tumor Reduction Rate: A Retrospective Case-Control Study

Yao L, Liu X, Wang M, Yu K, Xu S, Qiu P, Lv Z, Zhang X, Xu Y

Purpose: We aimed to identify effectiveness-associated indicators and evaluate the optimal tumor reduction rate (TRR) after two cycles of neoadjuvant chemotherapy (NAC) in patients with invasive breast cancer. Methods: This retrospective...
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The relationships of perceived susceptibility, perceived severity, and subjective norms with COVID-19 preventive behaviors: a secondary data analysis comparing adolescents and emerging adults in South Korea

Park S, Oh S

Purpose: Based on the health belief model and theory of planned behavior, this study investigated how age group (adolescence and emerging adulthood) moderated the relative effects of perceived susceptibility, perceived...
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Chronic Reserpine Administration for Depression Modeling in Zebrafish

Kim S, Han C, Ko YH, Kim YK, Yoon HK, Lee J, Kim S, Lee C, Shin C

Objectives This study aims to develop valid experimental models for depression through chronic reserpine exposure to zebrafish (Danio rerio). Methods The effect of chronic reserpine on zebrafish behavior in the novel tank was...
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Prognostication in myeloproliferative neoplasms, including mutational abnormalities

Hong J

Increasing knowledge of the molecular features of myeloproliferative neoplasms (MPNs) is being combined with existing prognostic models based on clinical, laboratory, and cytogenetic information. Mutation-enhanced international prognostic systems (MIPSS) for...
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Risk Factors for Various Cognitive Function Decline Trajectories in Adults Over 40 Years of Age: A Retrospective Cohort Study

Han S, Lee JY, Cho Si, Oh DJ, Yoon DH

Objective The aims of our study were to identify distinct trajectories of cognitive function using the group-based trajectory model. We also investigate which demographic factors act as risk factors for...
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Preclinical Evaluation of an Everolimus-Eluting Bioresorbable Vascular Scaffold Via a Long-Term Rabbit Iliac Artery Model

Park DS, Jeong MH, Jin YJ, Na MH, Sim DS, Kim M, Cho KH, Hyun DY, Oh S, Kim JH, Lim KS, Park JK, Kim HK, Hong YJ, Kim JH, Ahn Y, Kim JH

BACKGROUND: Biodegradable poly (l-lactic acid) (PLLA), a bio safe polymer with a large elastic modulus, is widely used in biodegradable medical devices. However, because of its poor mechanical properties, a...
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The Efficacy and Safety of a Human Perirenal Adipose TissueDerived Stromal Vascular Fraction in an Interstitial Cystitis Rat Model

Ha JY, Lee EH, Chun SY, Lee JN, Ha YS, Chung JW, Yoon BH, Jeon M, Kim HT, Kwon TG, Yoo ES, Kim BS

BACKGROUND: Interstitial cystitis (IC) is a chronic and intractable disease that can severely deteriorate patients’ quality of life. Recently, stem cell therapy has been introduced as a promising alternative treatment...
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Improving Tuberculosis Medication Adherence: The Potential of Integrating Digital Technology and Health Belief Model

Sazali MF, Rahim SSSA, Mohammad AH, Kadir F, Payus AO, Avoi R, Jeffree MS, Omar A, Ibrahim MY, Atil A, Tuah NM, Dapari R, Lansing MG, Rahim AAA, Azhar ZI

Tuberculosis (TB) is a significant public health concern. Globally, TB is among the top 10 and the leading cause of death due to a single infectious agent. Providing standard anti-TB...
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Tissue Engineered Mini-Cornea Model for Eye Irritation Test

Kim SH, Jo SH, Kim BK, Park SH

BACKGROUND: Eye irritation tests with animals have been conducted for a long time. However, the subjective decision to irritation, the anatomic/physiologic difference between species and humans, and ethical issues are...
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Assessment of the changes in cardiac sympathetic nervous activity using the pupil size changes measured in seated patients whose stellate ganglion is blocked by interscalene brachial plexus block

Kim E, Lim JA, Choi CH, Lee SY, Kwak S, Kim J

Background: As a side effect of interscalene brachial plexus block (ISBPB), stellate ganglion block (SGB) causes reductions in pupil size (Horner’s syndrome) and cardiac sympathetic nervous activity (CSNA). Reduced CSNA...
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Hycanthone Inhibits Inflammasome Activation and Neuroinflammation-Induced Depression-Like Behaviors in Mice

Boo KJ, Gonzales EL, Remonde CG, Seong JY, Jeon SJ, Park YM, Ham BJ, Shin CY

Despite the various medications used in clinics, the efforts to develop more effective treatments for depression continue to increase in the past decades mainly because of the treatment-resistant population, and...
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The application of the health belief model in oral health-related dietary behavior

Na JY, Oh HW, Lee HS

Objectives: This study aimed to investigate the relationship between oral health beliefs and oral health-related dietary behavior. Methods: The participants of this cross-sectional study were 728 middle school students living in...
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Endovenous radiofrequency ablation using a new bipolar electrode in a canine model: a new endovenous radiofrequency electrode

Hwang JH, Park SW, Min J, Yang WY, Kwon YW, Hwang JJ, Kim JS, Lee SA, Chee HK

Purpose: This study aimed to determine the effectiveness and safety of a newly developed endovenous radiofrequency (RF) catheter compared with that of the existing RF catheter in a canine model. Methods:...
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Defining the optimal technique for endoscopic ultrasound shear wave elastography: a combined benchtop and animal model study with comparison to transabdominal shear wave elastography

Wang TJ, Ryou M

Background/Aims: Shear wave elastography (SWE) is used for liver fibrosis staging based on stiffness measurements. It can be performed using endoscopic ultrasound (EUS) or a transabdominal approach. Transabdominal accuracy can...
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Mechanistic modelling for African swine fever transmission in the Republic of Korea

Kim E, Lim JS, Pak SI

Under the current African swine fever (ASF) epidemic situation, a science-based ASF-control strategy is required. An ASF transmission mechanistic model can be used to understand the disease transmission dynamics among...
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Effects of Mesenchymal Stem Cells Treatment on Radiation-Induced Proctitis in Rats

Kim WH, Yoo JH, Yoo IK, Kwon CI, Hong SP

Purpose: There are no effective treatment methods with which to control complications of radiation proctitis with fistula or recurrent bleeding following radiation treatment for prostate, cervical, or rectal cancer. Mesenchymal...
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The Effects of Job Quality on the Health of Wage Workers: Congruence between the Hard and Soft Job Quality

Kim K

Background This study analyzes the linear and non-linear effects of the hard and soft dimensions of job quality on the overall health of wage workers. It also examines the congruence or...
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