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Longitudinal Muscle Dysfunction in Achalasia Esophagus and Its Relevance

Mittal RK, Hong SJ, Bhargava V

  • KMID: 2325785
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):126-136.
Muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Goal of this review is to summarize the role of longitudinal muscle in physiology and pathophysiology of...
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Morphology of the Esophageal Hiatus: Is It Different in 3 Types of Hiatus Hernias?

Kumar D, Zifan A, Ghahremani G, Kunkel DC, Horgan S, Mittal RK

  • KMID: 2500649
  • J Neurogastroenterol Motil.
  • 2020 Jan;26(1):51-60.
  • doi: 10.5056/jnm18208
Background/Aims The esophageal hiatus is formed by the right crus of the diaphragm in the majority of subjects. Contraction of the hiatus exerts a sphincter-like action on the lower esophageal...
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Esophageal Submucosal Injection of Capsaicin but Not Acid Induces Symptoms in Normal Subjects

Lee RH, Korsapati , Bhalla V, Varki N, Mittal RK

  • KMID: 2327948
  • J Neurogastroenterol Motil.
  • 2016 Jul;22(3):436-443.
  • doi: 10.5056/jnm15166
BACKGROUND/AIMS: Transient receptor potential vanilloid-1 (TRPV1) is a candidate for mediating acid-induced symptoms in the esophagus. We conducted studies to determine if the presence of acid in the mucosa/submucosa and...
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Length Tension Function of Puborectalis Muscle: Implications for the Treatment of Fecal Incontinence and Pelvic Floor Disorders

Mittal RK, Sheean G, Padda BS, Rajasekaran MR

  • KMID: 2381219
  • J Neurogastroenterol Motil.
  • 2014 Oct;20(4):539-546.
  • doi: 10.5056/jnm14033
BACKGROUND/AIMS: External anal sphincter (EAS) and puborectalis muscle (PRM) play important role in anal continence function. Based on length-tension measurement, we recently reported that the human EAS muscle operates at...
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