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Effects of monthly minodronate with or without eldecalcitol addition in osteoporosis patients with rheumatoid arthritis: An 18-month prospective study

Suzuki T, Nakamura Y, Kato H

OBJECTIVES: Increasing bone mineral density (BMD) to reduce fracture risk is a primary goal of osteoporosis treatment. This prospective, observational study evaluates the effects of monthly minodronate (MIN; 50 mg)...
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Influence on the bone mineral density and bone metabolism marker after the interruption and reinitiation of monthly minodronate therapy in postmenopausal women with osteoporosis

Okimoto N, Arita S, Akahoshi S, Baba K, Fukuhara S, Ishikura T, Yoshioka T, Fuse Y, Okamoto K, Menuki K, Sakai A

OBJECTIVES: The purpose of this study was to investigate the influences of interruption and reinitiation of monthly minodronate therapy on the bone mineral density (BMD) and bone metabolism markers in...
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Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study

Tanaka M, Nakamura Y, Itoh S, Kato Y

OBJECTIVES: This is an open labeled and retrospective cohort study which compared the effectiveness and safety of ibandronate (IBN) and minodronate (MIN) combined with eldecalcitol (ELD) in primary osteoporosis of...
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Monthly minodronate inhibits bone resorption to a greater extent than does monthly risedronate

Kamimura M, Nakamura Y, Ikegami S, Komatsu M, Uchiyama S, Kato H

As a bisphosphonate, minodronate (MIN) is one of the strongest inhibitors of bone resorption. However, there have been no reports directly comparing the antiresorptive effects of monthly MIN with those...
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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

Segawa T, Miyakoshi , Kasukawa Y, Aonuma H, Tsuchie H, Shimada Y

  • KMID: 2309513
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):30-37.
OBJECTIVES: Reduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study...
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