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From tumor hypoxia to cancer progression: the implications of hypoxia-inducible factor-1 expression in cancers

Nurwidya F, Takahashi , Minakata K, Murakami A, Takahashi

Hypoxia, defined as a decrease of tissue oxygen levels, represents a fundamental pathophysiological condition in the microenvironment of solid tumors. Tumor hypoxia is known to be associated with radio/chemo-resistance and...
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