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Investigation of the Proarrhythmic Effects of Antidepressants according to QT Interval, QT Dispersion and T Wave Peak-to-End Interval in the Clinical Setting

Okayasu H, Ozeki Y, Fujii K, Takano Y, Shinozaki , Ohrui M, Shimoda K

OBJECTIVE: Some antidepressants have been implicated as risk factors for QT prolongation, which is a predictor of sudden cardiac death. However, the QT interval is considered an imperfect biomarker for...
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A 10-Week Memantine Treatment in Bipolar Depression: A Case Report. Focus on Depressive Symptomatology, Cognitive Parameters and Quality of Life

Strzelecki D, Tabaszewska A, Barszcz Z, Jozefowicz O, Kropiwnicki P, Rabe-Jablonska J

  • KMID: 2316321
  • Psychiatry Investig.
  • 2013 Dec;10(4):421-424.
Memantine and other glutamatergic agents have been currently investigated in some off-label indications due to glutamatergic involvement in several psychoneurological disorders. We assumed that memantine similarly to ketamine may positively...
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Impulsive Behavior and Recurrent Major Depression Associated with Dandy-Walker Variant

Kim JH, Kim TH, Choi YC, Chung SC, Moon SW

  • KMID: 2316305
  • Psychiatry Investig.
  • 2013 Sep;10(3):303-305.
Reported herein is a case of recurrent major depression with impulse control difficulty in a 33-year-old man with Dandy-Walker variant. He was diagnosed as having major depressive disorder a year...
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Review of Antidepressants Treatment in Late-Life Depression

Yoon JH, Park SJ

  • KMID: 2334525
  • J Korean Geriatr Psychiatry.
  • 2013 Jun;17(1):8-13.
Late-life depression (LLD) refers to depressive syndromes defined in the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) and in the International Classification of Diseases-10 (ICD-10) that arise...
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No Association between Serotonin Receptor 2C-759C/T Polymorphism and Weight Change or Treatment Response to Mirtazapine in Korean Depressive Patients

Lee HY, Oh CK, Ham BJ, Chang HS, Paik JW, Won ES, Hahn SW, Shim SH, Kwon YJ, Jung HY, Lee MS

  • KMID: 2316267
  • Psychiatry Investig.
  • 2013 Jun;10(2):190-195.
OBJECTIVE: Activation of one or more serotonin (5-HT) receptors may play a role in mediating the antidepressant effects of serotonergic antidepressants. The serotonin 2C (5HT 2C) receptor is known to...
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Comparison of Antidepressants Tolerability in Cancer Patients Referred for Psychiatric Consultation

Ko E, Park JS, Ha J, Lim S, Kim TS, Ha JH, Paik JW, Lee BC, Choe BM, Lee KJ, Kim SW, Yang JC, Ko YH, Oh KS

  • KMID: 1432857
  • Korean J Psychosom Med.
  • 2013 Jun;21(1):3-10.
OBJECTIVES: Many patients diagnosed with cancer suffer from various psychiatric symptoms such as depression, anxiety and insomnia as well as cancer itself. Patients with cancer are more vulnerable to possible...
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Psychotrophic Drug Therapy of the Sexual Offenders or Paraphilia

Kang SH, Lee JW, Lim MH

  • KMID: 2287454
  • Korean J Psychopharmacol.
  • 2013 Apr;24(2):59-68.
Sexual violence crime causes severe trauma to victim's family as well as the victim, and its aftereffect which is hard to be healed can last for the entire lifetime. And...
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Korean Medication Algorithm for Depressive Disorder 2012 (III): The Subtypes of Depression

Park YM, Kim W, Lim ES, Lee HB, Jeong JH, Song HR, Seo JS, Hong JW, Wang HR, Bahk WM, Jon DI, Hong JP, Min KJ

  • KMID: 2287459
  • Korean J Psychopharmacol.
  • 2013 Jan;24(1):18-24.
OBJECTIVE: Recently, the pharmacotherapy including antidepressants in treating depression is widely used. However, as a result of newer agents that are continuously introduced, pharmacological treatment strategy is also changing. To...
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Effects of Antidepressant Treatment on Sexual Arousal in Depressed Women: A Preliminary fMRI Study

Yang JC, Park JI, Kim GW, Eun SJ, Lee MS, Han KL, Chae JH, Jeong GW

  • KMID: 2316230
  • Psychiatry Investig.
  • 2012 Dec;9(4):379-383.
OBJECTIVE: There was a recent study to explore the cerebral regions associated with sexual arousal in depressed women using functional magnetic resonance imaging (fMRI). The purpose of this neuroimaging study...
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Clinical Characteristics and Use of Antidepressants among Cancer Patients Referred for Psychiatric Consultation : A Korean Multicenter Survey

Park JS, Ha J, Lim S, Kim TS, Ha JH, Paik JW, Lee BC, Choe BM, Lee KJ, Kim SW, Yang JC, Ko YH, Oh KS

  • KMID: 2342421
  • J Korean Neuropsychiatr Assoc.
  • 2012 Nov;51(6):387-394.
OBJECTIVES: Antidepressants are frequently used for treatment of psychological distress among cancer patients. The aim of this study is to investigate the characteristics of psychiatric consultations and antidepressant use for...
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Changes of Medication Usage in Inpatients of Major Depressive Disorder: One University Hospital among Year 2001, 2006 and 2010

Song MK, Woo YS, Jun TY, Kim KS, Bahk WM

  • KMID: 2287466
  • Korean J Psychopharmacol.
  • 2012 Oct;23(4):166-175.
OBJECTIVE: Prescription patterns have changed rapidly due to development of new drugs, results of new researches, and increment of clinician's experience. The goal of this study was to examine and...
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The Tolerability of Mirtazapine Augmentation in Schizophrenic Patients Treated with Risperidone: A Preliminary Randomized Placebo-controlled Trial

Lee J, Cho SJ, Lee KS, Yook K, Choe AY, Lee S, Kim B, Kim KH, Choi TK, Lee SH

  • KMID: 2171263
  • Clin Psychopharmacol Neurosci.
  • 2011 Aug;9(2):73-77.
OBJECTIVE: Some patients with schizophrenia may need mirtazapine augmentation to improve negative and cognitive symptoms. However there have been a few studies about the tolerability of mirtazapine augmentation to antipsychotics...
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Psychiatric Co-morbidity and Efficacy of Mirtazapine Treatment in Young Subjects With Chronic or Cyclic Vomiting Syndromes: A Case Series

Coskun M, Alyanak B

  • KMID: 2325822
  • J Neurogastroenterol Motil.
  • 2011 Jul;17(3):305-311.
The aim of this case report was to evaluate the psychiatric co-morbidity and efficacy of mirtazapine treatment in young subjects with chronic or cyclic vomiting syndromes. This is a case...
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Mirtazapine Augmentation for Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction: A Retropective Investigation

Atmaca M, Korkmaz S, Topuz M, Mermi O

  • KMID: 2315928
  • Psychiatry Investig.
  • 2011 Mar;8(1):55-57.
The aim of the present study was to retrospectively identify sexual dysfunction changes in the patients under mirtazapine-augmented serotonin reuptake inhibito (SSRI) treatment. The study comprised medical records of 20...
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Korean Medication Algorithm Project for Generalized Anxiety Disorder 2009 (II) : Medication Algorithm & Long-Term Medication Treatment Strategy

Lee JY, Kim MS, Lee SH, Yang JC, Kim CH, Yu BH, Suh HS, Study Group for Korean Medication Algorithm Project for Generalized Anxiety Disorder 2009

  • KMID: 2341821
  • J Korean Neuropsychiatr Assoc.
  • 2010 Nov;49(6):553-563.
OBJECTIVES: This study was performed to investigate the consensus about medication algorithms, including long-term medication treatment strategies, in the treatment of generalized anxiety disorder (GAD). METHODS: The executive committee of the...
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An Association Study between Various Adrenergic Alpha 2 Receptor Polymorphisms and Treatment Response to Mirtazapine in Major Depression

Kim JW, Lim SW, Choi H, Kim SY, Myung WJ, Lee YJ, Song JH, Chung JW, Kim DK

  • KMID: 1462764
  • J Korean Geriatr Psychiatry.
  • 2010 Jun;14(1):20-26.
OBJECTIVES: Genetic differences may contribute to the inter-individual differences in treatment response to antidepressants among patients suffering from major depression. This study investigated a possible association of treatment response to...
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The Effects of Antidepressants on the Leptin, Adiponectin, and Adiponectin Receptor mRNA Expression in Model Diabetogenic Rats

Joe KH, Lee HJ, Kim DJ, Lee YS, Kee BS

  • KMID: 2341722
  • J Korean Neuropsychiatr Assoc.
  • 2010 Mar;49(2):217-225.
OBJECTIVES: Weight gain and glucose intolerance are the most common symptoms of metabolic syndrome. Certain patients complain of weight-change and hyperglycemia after receiving antidepressants. Our study evaluated the effects of...
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Antidepressant-Induced Sexual Dysfunction among Newer Antidepressants in a Naturalistic Setting

Lee KU, Lee YM, Nam JM, Lee HK, Kweon YS, Lee CT, Jun TY

  • KMID: 2315866
  • Psychiatry Investig.
  • 2010 Mar;7(1):55-59.
OBJECTIVE: Antidepressants used to treat depression are frequently associated with sexual dysfunction. Sexual side effects affect the patient's quality of life and, in long-term treatment, can lead to non-compliance and...
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Resolution of Pregabalin and Mirtazapine Associated Restless Legs Syndrome by Bupropion in a Patient with Major Depressive Disorder

Park YM, Lee HJ, Kang SG, Cho JH, Kim L

  • KMID: 2315856
  • Psychiatry Investig.
  • 2009 Dec;6(4):313-315.
Bupropion is a selective norepinephrine and dopamine reuptake inhibitor with no serotonergic activity, and is therefore an antidepressant with unique pharmacological properties. There are some reports that selective serotonin reuptake...
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The Effects of Antidepressants on the Energy Metabolism in LETO Rat

Jeon HT, Joe KH, Ahn YK, Kim HT, Kee BS

  • KMID: 2011066
  • Korean J Psychopharmacol.
  • 2009 Jul;20(4):194-204.
Objectives : A diverse range of adverse effects has been linked to the application of antidepressants for the treatment of depressive disorder. Recently, evidence has been emerging of the adverse...
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