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Dichloromethane-Induced Chemical Burn of the Hand: A Report of Two Cases

Han SH, Kim SM, Kim CK, Kim SH, Jo DI

Dichloromethane is widely used as a solvent in paint removers. Unlike inhalation injury, contact injury caused by dichloromethane is not well known. Two patients who had undergone skin grafting to...
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Anti-oxidative Effect of Piperine from Piper nigrum L. in Caenorhabditis elegans

Park HM, Kim JH, Kim DK

Piper nigrum L. (Piperaceae), which is a well-known food seasoning, has been used as a traditional medicine for the treatment of vomiting, abdominal pain, diarrhea and anorexia in Korea, China...
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Anti-inflammatory Activity of Standardized Fraction from Inula helenium L. via Suppression of NF-κB Pathway in RAW 264.7 Cells

Chun J, Song K, Kim YS

Inula helenium L. is rich source of eudesmane-type sesquiterpene lactones, mainly alantolactone and isoalantolactone, which have the various pharmacological functions. In this study, we examined the inhibitory effects of nitric...
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Chemical Constituents of Bark of Beilschmiedia kunstleri Gamble with Anticancer, Anti-Streptococcus pyogenes, Anti-Bacillus cereus and Anti Plesiomonas shigelloides Activities

Mollataghi A

Lauraceae is a family medicinal plant whose tubers possesses antimicrobial, and cytotoxic, such as antiparasitic and anti-inflammatory special effects and has been used for the medicine in the cure of...
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Aflatoxin M1 Contamination Levels in Cheeses Sold in Isfahan Province, Iran

Sharifzadeh A, Ghasemi-Dehkordi P, Foroughi M, Mardanpour-Shahrekordi E, Ramazi S

OBJECTIVES: Aflatoxin M1 (AFM1)-contaminated dairy products pose serious human health risks, causing liver and renal failure if consumed. They are also related to decreased milk and egg production in infected...
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Antimutagenic and Antioxidant Activities of Thai Rice Brans

Insuan O, Chariyakornkul A, Rungrote Y, Wongpoomchai R

BACKGROUND: Rice bran is the outer layer of the rice grain, and contains high amounts of bioactive phytochemicals. Here, we investigated and compared chemopreventive properties of purple and white rice...
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Bioassay-Guided Isolation and Identification of Compounds from Arecae Pericarpium with Anti-inflammatory, Anti-oxidative, and Melanogenesis Inhibition Activities

Indriana A, Lee KJ, Kim YS

This study describes the anti-inflammatory, anti-oxidant, and melanogenesis inhibition activities of methanol extract and various organic solvent fractions of Arecae Pericarpium. We examined the inhibition of lipopolysaccharide (LPS)-induced nitric oxide...
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Phenolic Constituents and Their Anti-inflammatory Activity from Echinochloa utilis Grains

Nguyen DH, Zhao BT, Le DD, Kim KY, Kim YH, Yoon YH, Ko JY, Woo KS, Woo MH

Seven phenolic compounds including p-coumaric acid (1), 4-hydroxybenzoic acid (2), 4-hydroxybenzaldehyde (3), vanillic acid (4), luteolin (5), acacetin (6), and tricin (7), were isolated from the methylene chloride and ethyl...
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IgA nephropathy in a laboratory worker that progressed to end-stage renal disease: a case report

Min B, Kim G, Kang T, Yoon C, Cho SI, Paek D

BACKGROUND: IgA nephropathy (IgAN) is the most common form of glomerulonephritis, a principal cause of end-stage renal disease (ESRD) worldwide. The mechanisms of onset and progression of IgAN have not...
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Antioxidant activity and anti-inflammatory activity of ethanol extract and fractions of Doenjang in LPS-stimulated RAW 264.7 macrophages

Kwak CS, Son D, Chung YS, Kwon YH

BACKGROUND/OBJECTIVES: Fermentation can increase functional compounds in fermented soybean products, thereby improving antioxidant and/or anti-inflammatory activities. We investigated the changes in the contents of phenolics and isoflavones, antioxidant activity and...
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A Clinical Analysis of Patients Who Visited Emergency Department due to Chemical Incident Occurred at Industrial Place: A Retrospective Study

Shin HJ, Oh SK, Yoo BD, Jun DH, Lee DH, Woo KH, Yoon SY, Choi SY

  • KMID: 2133232
  • J Korean Soc Clin Toxicol.
  • 2015 Dec;13(2):78-86.
PURPOSE: The purpose of this study is to understand what kinds of chemical substances have been used annually and to investigate incidents that occurred due to chemical hazard release and...
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Phenolic Compounds from the Leaves of Stewartia pseudocamellia Maxim. and their Whitening Activities

Roh HJ, Noh HJ, Na CS, Kim CS, Kim KH, Hong CY, Lee KR

The half-dried leaves of Stewartia. pseudocamellia were extracted with hot water (SPE) and partitioned with n-hexane (SPEH), dichloromethane (SPED), and ethyl acetate (SPEE) successively. SPE and SPEE showed significant inhibitory...
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Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells

Lee HS, Kim EJ, Kim SH

BACKGROUND/OBJECTIVES: Inonotus obliquus (I. obliquus, Chaga mushroom) has long been used as a folk medicine to treat cancer. In the present study, we examined whether or not ethanol extract of...
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Vitis amurensis Ruprecht root inhibited alpha-melanocyte stimulating hormone-induced melanogenesis in B16F10 cells

Jin KS, Oh YN, Hyun SK, Kwon HJ, Kim BW

BACKGROUND/OBJECTIVES: The root of Vitis amurensis Ruprecht, a sort of wild-growing grape, has been used in oriental medicine for treatment of skin ailments; however, its dermatological activity is not sufficiently...
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Development of a LC-MS/MS for Quantification of Venlafaxine in Human Plasma and Application to Bioequivalence Study in healthy Korean Subjects

Kang HK, Kang MA, Kim HJ, Park YS, Kim SH, Kang JS

  • KMID: 2317857
  • Transl Clin Pharmacol.
  • 2014 Jun;22(1):35-42.
A simple, rapid and selective liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is developed and validated for quantification of venlafaxine in human plasma with simple liquid-liquid extraction step consisted...
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Anti-carcinogenic effects of non-polar components containing licochalcone A in roasted licorice root

Park SY, Kim EJ, Choi HJ, Seon MR, Lim SS, Kang YH, Choi MS, Lee KW, Yoon Park

  • KMID: 2313737
  • Nutr Res Pract.
  • 2014 Jun;8(3):257-266.
BACKGROUND/OBJECTIVE: Licorice has been shown to possess cancer chemopreventive effects. However, glycyrrhizin, a major component in licorice, was found to interfere with steroid metabolism and cause edema and hypertension. The...
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Depressor action and vasorelaxation of methylene chloride fraction extracted from Rubus coreanum

Yu BS, Choi MS, Lim DY

INTRODUCTION: The present study was designed to examine whether methylene chloride (CH2Cl2) fraction extracted from Rubus coreanum affects the contractility of the isolated thoracic aortic strips and blood pressure of...
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Protective Effects of Alpinia katsumadai Extract Against Oxidative Stress

Lee EJ, Kim JH

  • KMID: 2170746
  • Int J Oral Biol.
  • 2011 Sep;36(3):149-154.
In the present study, total methanol extracts prepared from Alpinia katsumadai showed significant protective effects against the oxidative stress induced by hydrogen peroxide, UV-C or gamma-ray irradiation. These protective effects...
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Whitening Effects of Marine Pseudomonas Extract

Kang HY, Yoon TJ, Lee GJ

BACKGROUND: Bacteria associated with marine invertebrates are a rich source of bioactive metabolites. OBJECTIVE: The effects of marine bacteria extracts on pigmentation were investigated to find novel whitening agents. METHODS: The marine...
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Antifungal Effects of the Extracts and Essential Oils from Foeniculum vulgare and Illicium verum against Candida albicans

Park SH, Seong I

  • KMID: 1458590
  • Korean J Med Mycol.
  • 2010 Dec;15(4):157-164.
BACKGROUND: Candida albicans is a member of the normal flora of the skin, mucous membrane and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women in childbearing age, Majority...
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