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Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
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Epicatechin Prevents Methamphetamine-Induced Neuronal Cell Death via Inhibition of ER Stress

Kang Y, Lee JH, Seo YH, Jang JH, Jeong CH, Lee S, Jeong GS, Park B

Methamphetamine (METH) acts strongly on the nervous system and damages neurons and is known to cause neurodegenerative diseases such as Alzheimer's and Parkinson's. Flavonoids, polyphenolic compounds present in green tea,...
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Chronic administration of ketamine ameliorates the anxiety- and aggressive-like behavior in adolescent mice induced by neonatal maternal separation

Shin SY, Baek NJ, Han SH, Min SS

Ketamine has long been used as an anesthetic agent. However, ketamine use is associated with numerous side effects, including flashbacks, amnesia, delirium, and aggressive or violent behavior. Ketamine has also...
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Survival after Cardiac Arrest due to Acute Methamphetamine Poisoning: A Case Report

Mun YH, Kim JH

Drug abuse and its related problems are increasing continuously in Korea. One of the most frequently abused drugs is methamphetamine, but there are few medical report in Korea. This is...
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A Fatal Intracerebral Hemorrhage due to Chronic Methamphetamine Use

Na JY, Kim JJ, Park JT

The authors report a case of an otherwise healthy 33-year-old man who presented with intracerebral hemorrhage in the right frontal lobe following chronic methamphetamine use. An autopsy was performed within...
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A Clinical Review of Patients Who Visited Emergency Medical Center with Positive Methamphetamine Tests: A Single Institute Study

Ok YB, Kim JY, Lee KR, Hong DY, Baek KJ, Park SO, Kim JW, Kim SY

PURPOSE: Methamphetamine is an ongoing illegal drug problem worldwide, and its use in South Korea has spread over the last few years. In this study, a clinical review of patients...
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Associations of the Neighborhood Environment With Substance Use: A Cross-sectional Investigation Among Patients in Compulsory Drug Detention Centers in Thailand

Yangyuen S, Kanato M, Mahaweerawat U

OBJECTIVES: To identify the associations of characteristics of the neighborhood environment with substance abuse among clients receiving treatment for drug abuse in Thailand. METHODS: A cross-sectional study was conducted of 1128...
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A review of methods to estimate the visibility factor for bias correction in network scale-up studies

Haghdoost , Ahmadi Gohari M, Mirzazadeh A, Zolala F, Baneshi MR

Network scale-up is an indirect size estimation method, in which participants are questioned on sensitive behaviors of their social network members. Therefore, the visibility of the behavior affects the replies...
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Quantitative Electroencephalogram Abnormalities in Methamphetamine Dependence in Forensic Evaluation: Case Control Study

Hwang S, Choi J, Lyu M, Kim S, Kim K, Ahn J

In this study, we analyzed the quantitative electroencephalograms (EEGs) of forty-eight subjects (18 with methamphetamine dependence and 30 non-methamphetamine users as controls). Immediately following data collection, all personally identifying information...
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Influence of Betaxolol on the Methamphetamine Dependence in Mice

Kim BJ, Park JI, Eun HJ, Yang JC

OBJECTIVE: The noradrenaline system is involved in the reward effects of various kinds of abused drugs. Betaxolol (BTX) is a highly selective β1-antagonist. In the present study, we evaluated the...
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Simultaneous Thrombosis of the Left Anterior Descending Artery and the Right Coronary Artery in a 34-Year-Old Crystal Methamphetamine Abuser

Khaheshi I, Mahjoob MP, Esmaeeli S, Eslami V, Haybar H

This case report underscores that crystal methamphetamine abuse is an important cause of multivessel coronary thrombosis and raises doubts about the therapeutic options. The patient was a 34-year-old smoker and...
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Altitude May Contribute to Regional Variation in Methamphetamine Use in the United States: A Population Database Study

Kim TS, Kondo DG, Kim N, Renshaw PF

OBJECTIVE: Methamphetamine (MA) use rates in the United States (US) have consistently demonstrated geographical variation and have been higher in the West and Midwest. This uneven pattern of use could...
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A Pilot Study for Discovering Candidate Genes of Chromosome 18q21 in Methamphetamine Abusers: Case-control Association Study

Lee BD, Park JM, Lee YM, Moon ES, Jeong HJ, Chung YI, Rim HD

  • KMID: 2171130
  • Clin Psychopharmacol Neurosci.
  • 2014 Apr;12(1):54-64.
OBJECTIVE: It was previously suggested that the malic enzyme 2 (ME2) as the candidate gene for psychosis in fine mapping of chromosome 18q21. Chromosome 18q21 is also one of the...
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Association of the Neuronal Cell Adhesion Molecule (NrCAM) Gene Variants with Personality Traits and Addictive Symptoms in Methamphetamine Use Disorder

Yoo BK, Shim JC, Lee BD, Kim C, Chung YI, Park JM, Kim SG, Kim JH, Lee YM, Moon ES, Kwon DH

  • KMID: 2316233
  • Psychiatry Investig.
  • 2012 Dec;9(4):400-407.
OBJECTIVE: 1) To investigate the relationship between NrCAM polymorphisms and methamphetamine abuse in an ethnically homogenous Korean population. 2) To further support our findings by investigating the association among NrCAM...
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Temperament and Character in Cannabis and Methamphetamine Abusers

Kwon M, Min JA, Choi JH, Kim DJ

  • KMID: 2250300
  • Korean J Biol Psychiatry.
  • 2012 May;19(2):99-105.
OBJECTIVES: This study aims to identify temperament and characteristics of cannabis and methamphetamine abusers for elucidating psycho-biological variables related to certain substance abuse. METHODS: A total of 320 patients who registered...
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A Case of Fournier Gangrene after Penile Methamphetamine Injection

Moon HS, Lee JH, Choi HY, Park HY

  • KMID: 2298760
  • Korean J Androl.
  • 2010 Dec;28(3):223-225.
Fournier gangrene is a fulminant infection of the genitalia, perineum, or abdominal wall. It is a life threatening progressive disease that requires aggressive surgical therapy and broad spectrum antibiotic treatment....
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Multiple Organ Dysfunction Syndrome and Quadriplegia due to Acute Methamphetamine Intoxication: A Case Report

Kwon OY, Lee JS, Choi HS, Hong HP, Ko YG

Methamphetamine (MA) is an extremely addictive central nervous system stimulant. MA abuse has increased during the past three decades in Korea because it is cheap relatively and easily produced. Acute...
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The Usefulness of a Triage Kit for Detecting Abused Drugs

Kwak MK, Kim WY, Kang HD, Lee JH, Oh BJ, Kim W, Lim KS

BACKGROUND: The recovery and outcome of intoxicated patients depends on the kind of drugs they took and the total time of their initial management. The purpose of this study is...
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Gene Expression Profiling in C57BL/6 Mice Treated with the Anorectic Drugs Sibutramine and Phendimetrazine and Their Mechanistic Implications

Ko MJ, Choi HS, Ahn JI, Kim SY, Jeong HS, Chung HJ

  • KMID: 2166406
  • Genomics Inform.
  • 2008 Sep;6(3):117-125.
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered...
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Dopamine Transporter Density of the Basal Ganglia Assessed with I-123 IPT SPECT in Methamphetamine Abusers

Lee JR, Ahn BC, Kewn DH, Sung YO, Seo JH, Bae JH, Jeong SY, Lee SW, Yoo J, Lee J, Chi DY, Lee KB

  • KMID: 2307647
  • Korean J Nucl Med.
  • 2005 Dec;39(6):481-488.
PURPOSE: Functional imaging of dopamine transporter (DAT) defines integrity of the dopaminergic system, and DAT is the target site of drugs of abuse such as cocaine and methamphetamine. Functional imaging...
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