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Human Immunodeficiency Virus Infection and Gut Microbiota: A Review on Gut Microbiome Associated with Immune Activation and Metabolic Diseases

Joo EJ

This review provides the complex interaction between human immunodeficiency virus (HIV) infection and gut microbiota. HIV infection exerts chronic effects by impairing the immune system, closely linked with alterations in...
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Metagenomic analysis of viral genes integrated in whole genome sequencing data of Thai patients with Brugada syndrome

Chitcharoen S, Phokaew C, Mauleekoonphairoj J, Khongphatthanayothin A, Sutjaporn B, Wandee P, Poovorawan Y, Nademanee K, Payungporn S

Brugada syndrome (BS) is an autosomal dominant inheritance cardiac arrhythmia disorder associated with sudden death in young adults. Thailand has the highest prevalence of BS worldwide, and over 60% of...
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Urinary microbiome profile in men with genitourinary malignancies

Ahn HK, Kim K, Park J, Kim KH

Purpose: Recent advances in molecular biology technology have allowed identification of microbial communities in the urinary tract, and urinary microbiome is associated with various urological diseases. In this study, we...
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Changes in Gastric Microbial Composition before and after Helicobacter pylori Eradication Therapy

Park CH

Owing to advancements in next-generation sequencing and non-culture-based microbial research techniques, we have recognized that many bacterial taxa other than Helicobacter pylori (H. pylori) are present in the human stomach....
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Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant

Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ

PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and...
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Oral and Human Microbiome Research

Chung SK

In the past gut microbiome has been the main focus of microbiome research. Studies about the microbiome inside oral cavities and other organs are underway. Studies about the relationship between...
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Statistical Analysis of Metagenomics Data

Calle ML

Understanding the role of the microbiome in human health and how it can be modulated is becoming increasingly relevant for preventive medicine and for the medical management of chronic diseases....
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Comparison of differences in microbial compositions between negative controls and subject samples with varying analysis configurations

Kim H, Lee SP, Kang SM, Kang SY, Jung S, Lee SM

PURPOSE: Identifying microbial communities with 16S ribosomal RNA (rRNA) gene sequencing is a popular approach in microbiome studies, and various software tools and data resources have been developed for microbial...
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Human Resistome Study with Metagenomic Sequencing Data

Shin JH, Rho M

With the introduction of synthetic antibiotics, many lives including humans and animals have been saved against bacterial infection. An increasing level of antibiotics use, however, raises serious problems of multi-drug...
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Inflammasomes in antiviral immunity: clues for influenza vaccine development

Yamazaki T, Ichinohe T

Inflammasomes are cytosolic multiprotein complexes that sense microbial motifs or cellular stress and stimulate caspase-1-dependent cytokine secretion and cell death. Recently, it has become increasingly evident that both DNA and...
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Analysis of Oropharyngeal Microbiota between the Patients with Bronchial Asthma and the Non-Asthmatic Persons

Dang HT, Kim SA, Park HK, Shin JW, Park SG, Kim W

Bronchial asthma can be triggered by microbial agents in the oropharynx. This study was designed to identify the differences in microbiota of oropharynx of bronchial asthmatic patients in contrast to...
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The Human Microbiome Project: Beginning and Future Status

Murray PR

In 1884 Robert Koch and Friedrich Loeffler published Koch's Postulates defining our historical understanding of the relationship between an organism and infection: one organism: one disease. In the last decade...
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Bioprospecting Potential of the Soil Metagenome: Novel Enzymes and Bioactivities

Lee MH, Lee SW

The microbial diversity in soil ecosystems is higher than in any other microbial ecosystem. The majority of soil microorganisms has not been characterized, because the dominant members have not been...
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Current Status and Future Promise of the Human Microbiome

Kim BS, Jeon YS, Chun J

  • KMID: 2315410
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2013 Jun;16(2):71-79.
The human-associated microbiota is diverse, varies between individuals and body sites, and is important in human health. Microbes in human body play an essential role in immunity, health, and disease....
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Microflora Modulation of Motility

Quigley EM

  • KMID: 2326207
  • J Neurogastroenterol Motil.
  • 2011 Apr;17(2):140-147.
That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine,...
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