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Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappa B activation

Lee KY, Park JS, Jee YK, Rosen GD

  • KMID: 1121100
  • Exp Mol Med.
  • 2002 Dec;34(6):462-468.
TNF-related apoptosis-inducing ligand (TRAIL/Apo- 2L), a newly identified member of the TNF family promotes apoptosis by binding to the transmembrane receptors (TRAIL-R1/DR4 and TRAIL-R2/ DR5). TRAIL known to activate...
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Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells

Park H, Park OJ, Shin J, Choi Y

  • KMID: 1116197
  • Exp Mol Med.
  • 2005 Dec;37(6):524-532.
Receptor activator of NFkappaB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,...
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