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One-Year Clinical Outcomes After Diagnosis According to Early Medication Adherence in First-Episode Schizophrenia: A Nationwide, Health Insurance Data-Based Retrospective Cohort Study

Choi W, Joo SW, Ahn S, Choi YJ, Kim SM, Lee J

Objectives: Early pharmacologic intervention is considered necessary for improving the prognosis in patients with first-episode schizophrenia (FES). However, few nationwide population-based studies have focused on early medication adherence. We investigated...
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Persistence with Denosumab in Male Osteoporosis Patients: A Real-World, Non-Interventional Multicenter Study

Jeong C, Lee J, Kim J, Ha J, Jo K, Lim Y, Kim MK, Kwon HS, Sohn TS, Song KH, Kang MI, Baek KH

Background: Persistence with denosumab in male patients has not been adequately investigated, although poor denosumab persistence is associated with a significant risk of rebound vertebral fractures. Methods: We retrospectively evaluated 294...
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Overcoming Therapeutic Inertia as the Achilles’ Heel for Improving Suboptimal Diabetes Care: An Integrative Review

Chew BH, Mohd-Yusof BN, Lai PSM, Khunti K

The ultimate purpose of diabetes care is achieving the outcomes that patients regard as important throughout the life course. Despite advances in pharmaceuticals, nutraceuticals, psychoeducational programs, information technologies, and digital...
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Effects of the Insulin Therapy Adherence Program for Patients with Type 2 Diabetes: A Randomized Controlled Trial

Park KM, Son JT

Purpose: This study was conducted to evaluate the effects of the insulin therapy adherence program (INSTA GRAM) for patients with type 2 diabetes mellitus. Methods: This study examined a total...
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Improving Medication Adherence in Isolated Patients With Cognitive Impairment Using Automated Telephone Reminders

Kim MJ, Song JY, Jang Jw, Lee SY, Jhoo JH, Byeon GH, Kim Y

Background and Purpose: Medication adherence is essential for effective medical treatment. However, it is challenging for cognitively impaired patients. We investigated whether an automated telephone reminder service improves medication adherence and...
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Effects of medication adherence interventions for older adults with chronic illnesses: a systematic review and meta-analysis

Jeon HO, Chae MO, Kim A

This systematic review and meta-analysis aimed to understand the characteristics of medication adherence interventions for older adults with chronic illnesses, and to investigate the average effect size by combining the...
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Self-Monitoring of Blood Pressure and Feed-back Using APP in TReatment of UnconTrolled Hypertension (SMART-BP): A Randomized Clinical Trial

Choi DJ, Park JJ, Yoon M, Park SJ, Jo SH, Kim EJ, Kim SJ, Lee S

Background and Objectives: Self-monitoring of blood pressure (SMBP) is a reliable method used to assess BP accurately. However, patients do not often know how to respond to the measured BP...
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Adherence to and Dropout from Liraglutide 3.0 mg Obesity Treatment in a Real-World Setting

Ko HJ, Kim JW, Lim S

Background: The factors associated with non-adherence to obesity treatment using liraglutide 3.0 mg in a real-world setting remain elusive. Methods: We performed a secondary data analysis of 769 participants treated with...
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Adherence of bisphosphonate and decreased risk of clinical vertebral fracture in osteoporotic patients: A propensity score matching analysis

Kim S, Chung YS, Lee Y

Objectives: Bisphosphonate is associated with a decreased risk of vertebral fractures due to osteoporosis. However, there are limited studies on how poor compliance with bisphosphonate affects the risk of vertebral...
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The efficacy of denosumab in Korean male patients with osteoporosis

Jeong C, Ha J, Kim J, Lim Y, Kim MK, Kwon HS, Song KH, Kang MI, Baek KH

Background/Aims: Despite the prominence of denosumab as the number one prescribed anti-osteoporosis drug in Korea, the effects of denosumab in male osteoporosis patients were not researched sufficiently. Moreover, concerns on...
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Improvement in Medication Adherence after Pharmacist Intervention Is Associated with Favorable Clinical Outcomes in Patients with Ulcerative Colitis

Kim JS, Geum MJ, Son ES, Yu YM, Cheon JH, Kwon KH

Background/Aims: Although pharmacist intervention for patients with chronic diseases has been shown to improve medication adherence, few studies have evaluated its effects on the objective clinical outcomes. We investigated the...
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Adherence to Antipsychotic Drugs by Medication Possession Ratio for Schizophrenia and Similar Psychotic Disorders in the Republic of Korea: A Retrospective Cohort Study

Cho SJ, Kim J, Lee JY, Sohn JH

Objective: Pharmacotherapy is considered as an essential element in the treatment of psychotic disorders including schizophrenia. Discontinuation of antipsychotic drugs increases medical use and economic burden. Therefore, maintenance of medication...
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Impact of Depression and Social Support on Medication Adherence in Older Adults with Multimorbidity

Kim JE, Park JH, You MA, Seo EJ

Purpose: Medication adherence in older adults with multimorbidity is critical for self-care. The purpose of this cross-sectional study was to identify the factors that influence medication adherence in older adults...
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Osteoporotic Fractures among Selective Estrogen Receptor Modulator Users in South Korea: Analysis Using National Claims Database

Park JW, Lee YK, Choi Y, Ha YC

Background: We evaluated (1) compliance with selective estrogen receptor modulator (SERM) use in postmenopausal women; and (2) the risk of osteoporotic fractures according to compliance and other patient characteristics. Methods: National...
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The Effect of the Medication Management Service On the Cognitive Change and Community Service Usage

Bae M, Lee Ey, Kim Hh, Kim MS, Park S, Oh DJ, Lee JY

Objective: The purpose of this study was to investigate the efficacy of medication management as a method of early intervention in dementia. Methods: This study used data of survey and Mini-Mental...
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Medication Adherence in Korean Patients with Inflammatory Bowel Disease and Its Associated Factors

Oh K, Kwon EJ, Kim JH, Kim K, Lee JY, Hong HS, Hong SW, Park JH, Hwang SW, Yang DH, Ye BD, Byeon JS, Myung SJ, Yang SK, Park JY, Park SH

Objectives: It is important that inflammatory bowel disease (IBD) patients adhere to their prescribed medication regimens to avoid the repeat exacerbations, complications, or surgeries associated with this disorder. However, there...
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Effect of Immortal Time Bias Controlled Metformin for Cancer Development in Diabetic Patients

Seo HJ

Background: This study aimed to determine the effectiveness of metformin as first line oral hypoglycemic agent in diabetes patients in inhibiting cancer incidence, on the basis of the sample cohort...
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A study of relationships among tuberculosis knowledge, family support, and medication adherence in tuberculosis patients

Jang YR, Lee MA

Purpose: This study was conducted to investigate the effect of tuberculosis-related knowledge and family support on medication adherence in tuberculosis patients. Methods: The data were collected from 175 patients diagnosed with...
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Perceptions and Behaviors of Patients with Inflammatory Bowel Disease during the COVID-19 Crisis

Lee YJ, Kim KO, Kim MC, Cho KB, Park KS, Jang BI, obotCaCAiDG(

Background/Aims: This study aimed to investigate the perceptions and behaviors of patients with inflammatory bowel disease (IBD) during the early coronavirus disease 2019 (COVID-19) pandemic in the major epidemic area...
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Association of adherence measured by self-reported pill count with achieved blood pressure level in hypertension patients: a cross-sectional study

Ernawati I, Lubada EI, Lusiyani R, Prasetya RA

Background: Medication adherence plays an essential role in controlling blood pressure to reduce morbidity and mortality of hypertension disease. Thus, this study aimed to determine the association of medication adherence...
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