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Changes of Cytoskeletal System in Neurodegenerative Disease: Immunohistochemical Characterization of Neurofibrillary Changes Induced by Mitotic Spindle Inhibitors

Koo H

In experimental neurogenerative diseases, aluminum(Al) intoxication and axotomized sensory neurons showed an abnormal accumulation of neurofilaments(NF) in the neuronal perikarya. These NF contain phosphorylated(ph) epitopes that are not detectable in...
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