- The beneficial influence of rhubarb on 5-fluorouracil-induced ileal mucositis and the combined role of aquaporin-4, tumour necrosis factor-α, nuclear factor-kappa B & matrix metalloproteinase-9 in rat model: histological study
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Kamar SS, Baky MH, Omar AI
- KMID: 2503452
- Anat Cell Biol.
- 2020 Jun;53(2):228-239.
- doi: 10.5115/acb.20.014
A 5-fluorouracil (5-FU) is used for cancer treatment despite its cytotoxic sequelae on healthy cells, especially the rapid proliferating ones. Intestinal mucositis is one of the most frequent chemotherapeutic debilitating... -
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- The Correlation between Tear Matrix Metalloproteinase-9 Concentration and Clinical Findings in Dry Eye Disease
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Kim HR, Lee HK
- KMID: 2466163
- J Korean Ophthalmol Soc.
- 2019 Dec;60(12):1140-1147.
- doi: 10.3341/jkos.2019.60.12.1140
PURPOSE: To investigate the correlation between the matrix metalloproteinase-9 (MMP-9) concentration, and subjective symptoms and objective signs in dry eye patients. METHODS: We retrospectively reviewed the medical records of 134 eyes... -
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- Chronic Cerebral Hypoperfusion Induces Alterations of Matrix Metalloproteinase-9 and Angiopoietin-2 Levels in the Rat Hippocampus
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Kim MS, Choi BR, Lee YW, Kim DH, Han YS, Jeon WK, Han JS
- KMID: 2419339
- Exp Neurobiol.
- 2018 Aug;27(4):299-308.
- doi: 10.5607/en.2018.27.4.299
Angiogenic factors contribute to cerebral angiogenesis following cerebral hypoperfusion, and understanding these temporal changes is essential to developing effective treatments. The present study examined temporal alterations in angiogenesis-related matrix metalloproteinase-9... -
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- HemoHIM, a herbal preparation, alleviates airway inflammation caused by cigarette smoke and lipopolysaccharide
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Shin NR, Kim SH, Ko JW, Park SH, Lee IC, Ryu JM, Kim JC, Shin IS
- KMID: 2375271
- Lab Anim Res.
- 2017 Mar;33(1):40-47.
- doi: 10.5625/lar.2017.33.1.40
HemoHIM, herbal preparation has designed for immune system recovery. We investigated the anti-inflammatory effect of HemoHIM on cigarette smoke (CS) and lipopolysaccharide (LPS) induced chronic obstructive pulmonary disease (COPD) mouse... -
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- Effect of Epigallocatechin-3-Gallate on PMA-Induced MUC5B Expression in Human Airway Epithelial Cells
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Song EJ, Bae CH, Kim JY, Kim YW, Park SY, Song SY, Kim YD
- KMID: 2278432
- Clin Exp Otorhinolaryngol.
- 2013 Dec;6(4):237-242.
OBJECTIVES: Among the inflammatory mediators, phorbol 12-myristate 13-acetate (PMA) is associated with the regulation of MUC5B expression in the airway epithelial cells. Epigallocatechin-3-gallate (EGCG) is the major component of green... -
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- Rhinitis Patients With Sputum Eosinophilia Show Decreased Lung Function in the Absence of Airway Hyperresponsiveness
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Yang MS, Lee HS, Kim MH, Song WJ, Kim TW, Kwon JW, Kim SH, Park HW, Chang YS, Cho SH, Min KU
- KMID: 2260317
- Allergy Asthma Immunol Res.
- 2013 Jul;5(4):232-238.
- doi: 10.4168/aair.2013.5.4.232
PURPOSE: Sputum eosinophilia is observed frequently in patients with rhinitis. Sputum eosinophilia in patients with non-asthmatic allergic rhinitis has been suggested to be related to nonspecific airway hyperresponsiveness (AHR). However,... -
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- Anti-Inflammatory, Antioxidant, Anti-Angiogenic and Skin Whitening Activities of Phryma leptostachya var. asiatica Hara Extract
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Jung HJ, Cho YW, Lim HW, Choi H, Ji DJ, Lim CJ
- KMID: 2170689
- Biomol Ther.
- 2013 Jan;21(1):72-78.
This work aimed to assess some pharmacological activities of P. leptostachya var. asiatica Hara. The dried roots of P. leptostachya var. asiatica Hara were extracted with 70% ethanol to generate... -
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- Effect of resveratrol on the metastasis of 4T1 mouse breast cancer cells in vitro and in vivo
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Lee HS, Ha AW, Kim WK
- KMID: 2313607
- Nutr Res Pract.
- 2012 Aug;6(4):294-300.
We investigated the effects of resveratrol on metastasis in in vitro and in vivo systems. 4T1 cells were cultured in the presence of various concentrations (0-30 micromol/L) of resveratrol. For... -
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- The Effect of Platelet-rich Plasma on Wounds of OLETF Rats Using Expression of Matrix Metalloproteinase-2 and -9 mRNA
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Shin HS, Oh HY
- KMID: 1921072
- Arch Plast Surg.
- 2012 Mar;39(2):106-112.
- doi: 10.5999/aps.2012.39.2.106
BACKGROUND: Complicated diabetic patients show impaired, delayed wound healing caused by multiple factors. A study on wound healing showed that platelet-rich plasma (PRP) was effective in normal tissue regeneration. Nonetheless,... -
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- The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells
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Bae CH, Chen SM, Lee HM, Song SY, Kim YD
- KMID: 2166398
- Clin Exp Otorhinolaryngol.
- 2011 Dec;4(4):177-183.
OBJECTIVES: Doxycycline is commonly used in medicine for its bacteriostatic antimicrobial properties. Recent studies have reported that doxycycline also has anti-inflammatory effects. Matrix metalloproteinase (MMP)-9 has been found to be... -
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- The Increased Expression of Matrix Metalloproteinase-9 Messenger RNA in the Non-lesional Skin of Patients with Large Plaque Psoriasis Vulgaris
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Lee SE, Lew W
- KMID: 2172061
- Ann Dermatol.
- 2009 Feb;21(1):27-34.
- doi: 10.5021/ad.2009.21.1.27
BACKGROUND: A difference of the interleukin-18 (IL-18) mRNA expression among several proinflammatory genes was previously observed between large plaque (LP) psoriasis patients (more than 5 cm lesions are typical) and... -
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- Early and Late Changes of MMP-2 and MMP-9 in Bleomycin-Induced Pulmonary Fibrosis
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Kim JY, Choeng HC, Ahn C, Cho SH
- KMID: 1782970
- Yonsei Med J.
- 2009 Feb;50(1):68-77.
- doi: 10.3349/ymj.2009.50.1.68
PURPOSE: Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of pulmonary fibrosis. To understand the role of MMP-2 and MMP-9 in pulmonary fibrosis, we evaluated the sequential dynamic change... -
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- Effects of (-)-Epigallocatechin-3-gallate on Brain Infarction and the Activity Change of Matrix Metalloproteinase-9 Induced by Middle Cerebral Artery Occlusion in Mice
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Qian YR, Kook JH, Hwang S, Kim DK, Kim JK
- KMID: 2285330
- Korean J Physiol Pharmacol.
- 2007 Jun;11(3):85-88.
Matrix metalloproteinases (MMPs) can degrade a wide range of extracellular matrix components. It has been reported that MMP-9 are activated after focal ischemia in experimental animals. (-)-Epigallocatechin-3-gallate (EGCG), a major... -
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- alpha-Lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity
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Kim HS, Kim HJ, Park KG, Kim YN, Kwon TK, Park JY, Lee KU, Kim JG, Lee IK
- KMID: 1103686
- Exp Mol Med.
- 2007 Feb;39(1):106-113.
The migration of vascular smooth muscle cells (VSMCs) into the intima, an important step in injury-induced neointimal hyperplasia, requires the activation of nuclear factor-kappaB (NF-kappaB) and the consequent up-regulation of... -
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- Effect of Curcumin on Cancer Invasion and Matrix Metalloproteinase-9 Activity in MDA-MB-231 Human Breast Cancer Cell
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Bang MH, Kim WK
- KMID: 2270062
- Korean J Nutr.
- 2006 Dec;39(8):756-761.
Curcumin has been known for its anti-proliferative and apoptotic effects on several cancer cells. We examined the inhibitory effects of curcumin on cancer cell adhesion, motility, invasion and matrix metalloproteinase-9... -
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- Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 after Administration of Endotoxin in Diabetic Rats
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Seo KH, Choi JS, Na JO, Uh ST, Kim YH, Park CS
- KMID: 1970265
- Tuberc Respir Dis.
- 2006 Sep;61(3):256-264.
- doi: 10.4046/trd.2006.61.3.256
BACKGROUND: An acute lung injury(ALI) is characterized by the recruitment, activation, and apoptosis of inflammatory cells, numerous products released by inflammatory cells such as reactive oxygen species, inflammatory mediators, and... -
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- Functional Polymorphism in the Promoter Region of Matrix Metalloproteinase-9 is Strongly Associated with Acute Myocardial Infarction
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Kim PJ, Chang K, Koh YS, Seung KB, Baek SH, Shin WS, Lim SH, Kim JH, Hong SJ, Choi KB
- KMID: 2227161
- Korean Circ J.
- 2005 Feb;35(2):192-196.
- doi: 10.4070/kcj.2005.35.2.192
BACKGROUND AND OBJECTIVES: Matrix metalloproteinase-9 (MMP-9) plays an important role in the genesis of atherosclerotic plaque rupture and acute coronary syndrome (ACS), including an acute myocardial infarction (AMI). A single... -
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- The Plasma Level of Matrix Metalloproteinase (MMP)-2, -9 between Antepartum and Postpartum Period in Preeclampsia
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Chang HJ, Yang JI, Kim HB, Kim HS, Ryu HS, Oh KS
- KMID: 2077113
- Korean J Obstet Gynecol.
- 2004 Aug;47(8):1487-1491.
OBJECTIVE: To evaluate the changes of plasma MMP-2, -9 levels in preeclampsia between antepartum and postpartum periods, and compare with normotensive pregnant. METHODS: Plasma MMP-2, -9 levels were determined with enzyme-linked... -
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- Increased Tear TNF-alpha and MMP-9 in Patients with Necrotizing Scleritis after Pterygium Excision
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Shin JC, Im CY, Lee JH, Seo KY
- KMID: 2126029
- J Korean Ophthalmol Soc.
- 2004 May;45(5):720-724.
PURPOSE: We collected tear or scleral tissues of necrotizing scleritis after pterygium excision, and evaluated them for tumor necrosis factor (TNF)-alpha and matrix metalloproteinase (MMP)-9 to elucidate the molecular basis... -
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- The Changes of Matrix Metalloproteinase-9 Expression in the Gastric Antral Mucosa after Helicobacter pylori Eradication: Immunohistochemical Study
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Ahn HS, Kim IH, Lee SO, Kang MJ, Kim DG, Lee ST
- KMID: 772611
- Korean J Gastroenterol.
- 2004 Feb;43(2):90-95.
BACKGROUND/AIMS: In this study, we analysed the changes of matrix metalloproteinase-9 (MMP-9) expression in the gastric antral epithelium in respect to H. pylori eradication. METHODS: Twenty patients with H.... -
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