- The Effectiveness of Antibiotic Macrolides Compared to Placebo for the Treatment of Pityriasis Rosea: A Systematic Review and Meta-analysis
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Kim WI, Heo JY, Park T, Kim S, Cho MK
- KMID: 2514428
- Korean J Dermatol.
- 2021 Mar;59(3):181-187.
Background: Pityriasis rosea is a self-limiting, acute, or subacute inflammatory skin disease that usually starts with a herald patch on the trunk and progresses to a generalized rash over the... -
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- Antaroide, a Novel Natural Nine-Membered Macrolide, Inhibits Melanin Biosynthesis in B16F10 Murine Melanoma Cells
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Ryu MJ, Baek EK, Kim S, Seong CN, Yang I, Lim KM, Nam SJ
- KMID: 2510130
- Biomol Ther.
- 2021 Jan;29(1):98-103.
- doi: 10.4062/biomolther.2020.064
Abstract The demand for natural substances with anti-melanogenic activity is increasing due to the recent interest in skin whitening. Intensive investigation on the culture broth of Streptomyces sp. SCO-736, a marine... -
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- Macrolide-refractory Mycoplasma pneumoniae pneumonia and hemophagocytic lymphohistiocytosis: case report and literature review
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Ma SY, Kim D, Lee J, Cho K, Suh JS, Lee SY
- KMID: 2511137
- Pediatr Emerg Med J.
- 2020 Dec;7(2):145-150.
- doi: 10.22470/pemj.2020.00094
Mycoplasma pneumoniae causes various extra-pulmonary complications. As a rare but fatal hematological complication, hemophagocytic lymphohistiocytosis (HLH) can be observed in children with M. pneumoniae infection. We report a case of... -
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- Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents
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Cho MA, Han S, Lim YR, Kim V, Kim H, Kim D
- KMID: 2442003
- Biomol Ther.
- 2019 Feb;27(2):127-133.
- doi: 10.4062/biomolther.2018.183
The study of the genus Streptomyces is of particular interest because it produces a wide array of clinically important bioactive molecules. The genomic sequencing of many Streptomyces species has revealed... -
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- The Effect of Macrolide Therapy on Bronchopulmonary Dysplasia in Ureaplasma-Positive Very Low Birth Weight Infants
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Kim S, Kim CY, Jung E, Kim H, Song WS, Lee BS, Kim EA, Kim KS
- KMID: 2421575
- Perinatology.
- 2018 Sep;29(3):107-113.
- doi: 10.14734/PN.2018.29.3.107
OBJECTIVE: Ureaplasma has been demonstrated the cause of short and long-term morbidities of preterm infants, especially such as bronchopulmonary dysplasia (BPD). This study aims to evaluate the influence of Ureaplasma... -
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- Related factors for and changes in clinical manifestations in mycoplasma pneumonia nonresponsive to macrolide treatment
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Tang CL, Ryu IK, Jung JH, Park JS, Kim HB
- KMID: 2408808
- Allergy Asthma Respir Dis.
- 2018 Mar;6(2):116-121.
- doi: 10.4168/aard.2018.6.2.116
PURPOSE: Mycoplasma pneumonia is known to be a major cause of community-acquired pneumonia in children. Macrolide has been the first-line treatment for mycoplasma pneumonia, but recently there has been an... -
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- Effects of Macrolide and Corticosteroid in Neutrophilic Asthma Mouse Model
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An TJ, Rhee CK, Kim JH, Lee YR, Chon JY, Park CK, Yoon HK
- KMID: 2420594
- Tuberc Respir Dis.
- 2018 Jan;81(1):80-87.
- doi: 10.4046/trd.2017.0108
BACKGROUND: Asthma is a disease of chronic airway inflammation with heterogeneous features. Neutrophilic asthma is corticosteroid-insensitive asthma related to absence or suppression of TH2 process and increased TH1 and/or TH17... -
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- Clinical Characteristics of Macrolide-Resistant Mycoplasma pneumoniae from Children in Jeju
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Kim YJ, Shin KS, Lee KH, Kim YR, Choi JH
- KMID: 2400436
- J Korean Med Sci.
- 2017 Oct;32(10):1642-1646.
- doi: 10.3346/jkms.2017.32.10.1642
Mycoplasma pneumoniae is the major pathogen of community-acquired pneumonia in children. The prevalence of macrolide-resistant M. pneumoniae (MRMP) is important owing to the limited alternative therapies for children. We analyzed... -
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- Efficacy of early steroid use in Mycoplasma pneumoniae pneumonia
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Kim HS, Song MG, Kim YW, Kim KS, Kim EY, Kim Y, Jang HI, Cho HM
- KMID: 2392404
- Allergy Asthma Respir Dis.
- 2017 Sep;5(5):280-286.
- doi: 10.4168/aard.2017.5.5.280
PURPOSE: The aim of this study was to evaluate whether or not the early use of steroid is useful for treating Mycoplasma pneumoniae pneumonia. METHODS: A prospective study was conducted on... -
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- Macrolide Resistance and Its Impacts on M. Pneumoniae Pneumonia in Children: Comparison of Two Recent Epidemics in Korea
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Kim JH, Kim JY, Yoo CH, Seo WH, Yoo Y, Song DJ, Choung JT
- KMID: 2378197
- Allergy Asthma Immunol Res.
- 2017 Jul;9(4):340-346.
- doi: 10.4168/aair.2017.9.4.340
PURPOSE: The aim of this study was to investigate the change in macrolide resistance rate in pediatric Mycoplasma pneumoniae pneumonia and to evaluate the influence of macrolide-resistant M. pneumoniae (MRMP)... -
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- Mechanism of resistance acquisition and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children
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Yang HJ, Song DJ, Shim JY
- KMID: 2383995
- Korean J Pediatr.
- 2017 Jun;60(6):167-174.
- doi: 10.3345/kjp.2017.60.6.167
Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics... -
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- Two patients with Mycoplasma pneumoniae pneumonia progressing to acute respiratory distress syndrome
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Kwon JE, Ahn JY, Choi BS
- KMID: 2379946
- Allergy Asthma Respir Dis.
- 2017 May;5(3):169-174.
- doi: 10.4168/aard.2017.5.3.169
Mycoplasma pneumoniae pneumonia is one of the most prevalent community-acquired pneumonias in pediatric patients. It commonly presents with mild respiratory symptoms and is well controlled by macrolide antibiotics. Rarely, it... -
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- Prevalence and clinical manifestations of macrolide resistant Mycoplasma pneumoniae pneumonia in Korean children
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Lee E, Cho HJ, Hong SJ, Lee J, Sung H, Yu J
- KMID: 2379625
- Korean J Pediatr.
- 2017 May;60(5):151-157.
- doi: 10.3345/kjp.2017.60.5.151
PURPOSE: Macrolide resistance rate of Mycoplasma pneumoniae has rapidly increased in children. Studies on the clinical features between macrolide susceptible-M. pneumoniae (MSMP) and macrolide resistant-M. pneumoniae (MRMP) are lacking. The... -
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- Is β-Lactam Plus Macrolide More Effective than β-Lactam Plus Fluoroquinolone among Patients with Severe Community-Acquired Pneumonia?: a Systemic Review and Meta-Analysis
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Lee JH, Kim HJ, Kim YH
- KMID: 2417588
- J Korean Med Sci.
- 2017 Jan;32(1):77-84.
- doi: 10.3346/jkms.2017.32.1.77
Adding either macrolide or fluoroquinolone (FQ) to β-lactam has been recommended for patients with severe community-acquired pneumonia (CAP). However, due to the limited evidence available, there is a question as... -
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- Expression and Regulation of Transcription Factor FoxA2 in Chronic Rhinosinusitis With and Without Nasal Polyps
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Luo Q, Zhang J, Wang H, Chen F, Luo X, Miao B, Wu X, Ma R, Luo X, Xu G, Shi J, Li H
- KMID: 2147954
- Allergy Asthma Immunol Res.
- 2015 Sep;7(5):458-466.
- doi: 10.4168/aair.2015.7.5.458
PURPOSE: Chronic rhinosinusitis (CRS) is characterized by the excessive production of mucus. However, the molecular mechanism underlying mucin overproduction in CRS with or without nasal polyps (CRSwNP and CRSsNP, respectively)... -
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- Effect of Prenatal and Postnatal Prophylaxis with Macrolide for Ureaplasma on the Development of Bronchopulmonary Dysplasia in Preterm Infants
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Jung E, Kim S, Jung YH, Lee J, Shin SH, Choi CW, Kim EK, Kim HS, Kim BI, Choi JH
- KMID: 2052165
- Neonatal Med.
- 2015 May;22(2):78-83.
- doi: 10.5385/nm.2015.22.2.78
PURPOSE: We aimed to evaluate the effects of two different macrolide prophylaxis protocols (prenatal and postnatal) for Ureaplasma on the development of bronchopulmonary dysplasia (BPD). METHODS: We retrospectively reviewed the medical... -
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- Macrolide Resistance of Mycoplasma pneumoniae and Its Detection Rate by Real-Time PCR in Primary and Tertiary Care Hospitals
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Uh Y, Hong JH, Oh KJ, Cho HM, Park SD, Kim J, Yoon KJ
- KMID: 1711313
- Ann Lab Med.
- 2013 Nov;33(6):410-414.
- doi: 10.3343/alm.2013.33.6.410
BACKGROUND: This study aimed to evaluate the prevalence of Mycoplasma pneumoniae in primary and tertiary care hospitals and its macrolide resistance rate. METHODS: Nasopharyngeal swabs were collected from 195 pediatric patients... -
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- Two Cases of Mycoplasma pneumoniae Pneumonia with A2063G Mutation in the 23S rRNA Gene in Siblings
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Hong JH, Chun JK, Uh Y, Oh KJ, Kim J, Yoon KJ
- KMID: 1781300
- Ann Lab Med.
- 2013 Jan;33(1):65-68.
- doi: 10.3343/alm.2013.33.1.65
We describe 2 cases of pneumonia caused by the same macrolide-resistant Mycoplasma pneumoniae in siblings. M. pneumoniae was identified using real-time PCR. Direct sequence analysis of the 23S rRNA gene... -
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- Mycoplasma pneumoniae Pneumonia Unresponsive to Macrolide Treatment
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Ji M, Sung H, Shim TS, Jang W, Kim MN
- KMID: 2312211
- Lab Med Online.
- 2012 Oct;2(4):226-231.
We present a case of community-acquired pneumonia (CAP) that developed in a previously healthy young woman. She was diagnosed with Mycoplasma pneumoniae pneumonia, but did not respond to macrolide treatment.... -
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- Clinical and Epidemiologic Characteristics of Mycoplasma pneumoniae Pneumonia in Adults During 2011 Epidemic
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Seo YB, Yang TU, Kim IS, Hong KW, Song JY, Cheong HJ, Kim WJ
- KMID: 2170381
- Infect Chemother.
- 2012 Oct;44(5):367-371.
- doi: 10.3947/ic.2012.44.5.367
BACKGROUND: Recent data regarding the clinical epidemiologic characteristics of Mycoplasma pneumoniae pneumonia in Korean adults are insufficient. This study was conducted in order to compare epidemics in different ages and... -
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