- Writing, erasing and reading histone lysine methylations
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Hyun K, Jeon J, Park K, Kim J
- KMID: 2382715
- Exp Mol Med.
- 2017 Apr;49(4):e324.
- doi: 10.1038/emm.2017.11
Histone modifications are key epigenetic regulatory features that have important roles in many cellular events. Lysine methylations mark various sites on the tail and globular domains of histones and their... -
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- Clinical Evaluation of Bendazac Lysine Salt in the Treatment of Senile and Adult Cataract
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Jo YS, Lee SM, Kim SH
- KMID: 2122707
- J Korean Ophthalmol Soc.
- 1986 Oct;27(5):763-767.
The lysine salt of Bendazac was orally administered(500mg daily) to 18 patients(29 eyes) suffering from senile or adult cataract, for the range of 2 to 6 months. The visual acuity... -
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- Eosinophilia-Myalgia Syndrome not Associated with the Ingestion of Nutritional Supplements
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Ahn SW, Shin BJ, Seo SJ, Hong CK
- KMID: 2362388
- Ann Dermatol.
- 2002 Mar;14(1):48-50.
- doi: 10.5021/ad.2002.14.1.48
Eosinophilia-myalgia syndrome(EMS) is a systemic illness that occurred as an epidemic by ingestion of over-the counter L-tryptophan preparation in the United States in October 1989. We report a Korean case of... -
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- Post-Translational Modification of Proteins in Toxicological Research: Focus on Lysine Acylation
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Lee S
- KMID: 2317819
- Toxicol Res.
- 2013 Jun;29(2):81-86.
Toxicoproteomics integrates the proteomic knowledge into toxicology by enabling protein quantification in biofluids and tissues, thus taking toxicological research to the next level. Post-translational modification (PTM) alters the three-dimensional (3D)... -
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- The Cytotoxicity of Poly - L - lysine in Different Concentration to Preadipocytes Harvested from Living Rats
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Kwon H, Seok Y, Rhie JW, Yoo G, Lim JS, Chung SH, Ahn ST
- KMID: 2041070
- J Korean Soc Plast Reconstr Surg.
- 2000 Nov;27(6):683-686.
Authors are trying to prove the fact that Poly-L-lysine (PLL) might be mixed with alginate to enhance cell-to- matrix adhesion. Before that experiment, the proportion of preadipocytes in cells obtained... -
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- Glyceraldehyde-Derived Advanced Glycation End Products Accumulate Faster Than N(ε)-(Carboxymethyl) Lysine
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Yokota M, Sekita M, Okano Y, Masaki H, Takeuchi M, Tokudome Y
- KMID: 2388959
- Ann Dermatol.
- 2017 Aug;29(4):508-511.
- doi: 10.5021/ad.2017.29.4.508
No abstract available. -
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- Anticataract Effects of Bendazac Lysine on Ultraviolet Induced Rat Cataract Based on Scheimpflug Camera
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Moon SC, Hong SJ, Park WC, Rho SH
- KMID: 2123686
- J Korean Ophthalmol Soc.
- 1997 Aug;38(8):1401-1409.
It has been known that ultraviolet B(UVB) light made an oxidative damage to lens proteins, lipids and nucleic acids to induce lens opacity. The aim of the study was to... -
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- Links between Serine Biosynthesis Pathway and Epigenetics in Cancer Metabolism
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Kim H, Park YJ
- KMID: 2417711
- Clin Nutr Res.
- 2018 Jul;7(3):153-160.
- doi: 10.7762/cnr.2018.7.3.153
Cancer metabolism is considered as one of major cancer hallmarks. It is important to understand cancer-specific metabolic changes and its impact on cancer biology to identify therapeutic potentials. Among cancer-specific... -
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- Histone lysine demethylases in mammalian embryonic development
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Shen H, Xu W, Lan F
- KMID: 2382716
- Exp Mol Med.
- 2017 Apr;49(4):e325.
- doi: 10.1038/emm.2017.57
Post-translational modifications, such as methylation, acetylation and phosphorylation, of histone proteins play important roles in regulating dynamic chromatin structure. Histone demethylation has become one of the most active research areas... -
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- Identification of Plasma Coagulation Factor XIII, Transglutaminase 3 and N epsilon-(gamma-glutamyl) lysine cross-Link in the Silicotic Nodule by Immunohistochemistry
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Kim YM, Kim YJ, Lee SY
- KMID: 2075000
- Korean J Occup Environ Med.
- 2003 Jun;15(2):173-180.
OBJECTIVES: This study was performed to examine the immunohistochemical distribution of TGase 1, 2, 3, coagulation factor XIII and N epsilon-(gamma-glutamyl) lysine cross-link in the silicotic nodules formed after an... -
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- Effect of Lysine -Limited Diets Containing Different Levels of L -Carnitine on Body Weight and Lipid Metabolism in Obesity -Induced Adult Rats
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Kim JK, Kim MK
- KMID: 2078407
- Korean J Nutr.
- 2007 Mar;40(2):118-129.
This study was performed to investigate the effect of lysine-limited diets containing different levels of L-carnitine on body weight and lipid metabolism in obesity-induced adult rats. Eight-month-old male Sprague-Dawley rats... -
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- Examination of lysine requirement of healthy young male adults on a Chinese habitual diet by the modified indicator amino acid oxidation method
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Tian Y, Peng J, Chen Y, Gong J, Xu H
- KMID: 2313712
- Nutr Res Pract.
- 2014 Feb;8(1):59-65.
There is currently no reference for intake of lysine for Chinese people; therefore, the present study was conducted to determine the lysine requirement of Chinese young male adults on a... -
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- The Measurement of Therapeutic Effect of Bendaline(R) in Early Cataract using with Scheimpflug Camera
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Lee JM, Moon SC, Park WC, Rho SH
- KMID: 2123569
- J Korean Ophthalmol Soc.
- 1996 Nov;37(11):1801-1807.
The Scheimpflug photography was used to evauate objectively changes in lens opacity at a month interval in 143 eyes of 78 patients affected by early cataract. from Dec. 1993 to... -
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- Increased lysine N-methylation of a 23-kDa protein during hepatic regeneration
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Choi YB, Ko MH, Shin CH, Kim KS, Hong KM, Paik MK, Park DE
- KMID: 1056226
- Exp Mol Med.
- 2005 Jun;37(3):155-160.
The methylation of a 23-kDa nuclear protein increased after partial hepatectomy and methylation returned to basal levels after the initial stage of regeneration. The methylating enzyme was partially purified from... -
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- Production and Evaluation of Immunoreactivity of Poly Lysine-Tagged Single Chain Fragment Variable (ScFv) Lym-1 Antibody for Direct Conjugation to Fluorescence Dye
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Jung JH, Choi TH, Woo KS, Chung WS, Kang JH, Jeong SY, Choi CW, Lim SM, Cheon GJ
- KMID: 1841154
- Nucl Med Mol Imaging.
- 2009 Oct;43(5):487-494.
PURPOSE: Small size of recombinant scFv antibody has many advantages such as rapid blood clearances and improved targeting antibodies to tumor region. On the other hand owing to small size,... -
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- A Case of Cystine Stone
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Yoon DK, Shin YS, Koh SK
- KMID: 2289654
- Korean J Urol.
- 1984 Feb;25(1):112-116.
Urinary tract calculi composed primarily of cystine are rare in adults and children. These are usually pure and found exclusively in patients with cystinuria. Cystinuria is an inherited defect in... -
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- Biochemical and Biological Progress in the Studies of Keratinization and Dyskeratosis
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Hideoki O, Kenji T, Makoto N, Yoshiike T
- KMID: 1679336
- Korean J Dermatol.
- 1985 Aug;23(4):429-440.
Recent topics of biochemical and biological progress in keratinization and dyskeratosis were reviewed and discussed. The main topics were as follows: (1) what is keratin (2) Differentiation of keratinocytes (keratinization),... -
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- Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies
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di Luccio
- KMID: 2171336
- J Cancer Prev.
- 2015 Jun;20(2):113-120.
- doi: 10.15430/JCP.2015.20.2.113
BACKGROUND: Multiple myeloma SET domain (MMSET)/nuclear receptor binding SET domain 2 (NSD2) is a lysine histone methyltransferase (HMTase) and bona fide oncoprotein found aberrantly expressed in several cancers, suggesting potential... -
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- The Global Histone Modification Patterns of Osteosarcoma
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Do SI, Lim SJ, Kim YW, Olvi LG, Santini-Araujo E, Park YK
- KMID: 1443747
- Korean J Pathol.
- 2011 Apr;45(2):146-150.
- doi: 10.4132/KoreanJPathol.2011.45.2.146
BACKGROUND: Epigenetic alteration may affect a patient's prognosis by altering the development and progression of the tumor. Some recent reports have identified a correlation between histone modification and patient outcome.... -
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- Ubiquitination of Aquaporin: in the kidney
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Lee YJ, Kwon TH
- KMID: 1464781
- Electrolyte Blood Press.
- 2009 Jun;7(1):1-4.
- doi: 10.5049/EBP.2009.7.1.1
Ubiquitination is known to be important for endocytosis and lysosomal degradation of aquaporin-2 (AQP2). Ubiquitin (Ub) is covalently attached to the lysine residue of the substrate proteins and activation and... -
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