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Prognostic outcome of treatment modalities for epidermal growth factor receptor-mutated advanced lung cancer

Jang SH, Lee DY, Jeong J, Choi WI

Background/Aims: The treatment of epidermal growth factor receptor (EGFR)-mutated lung cancer cases has shown remarkable development in the past two decades. However, there have been limited studies comparing the prognostic...
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Predictive Value of Interstitial Lung Abnormalities for Postoperative Pulmonary Complications in Elderly Patients with Early-stage Lung Cancer

Jeong WG, Kim YH, Lee JE, Oh IJ, Song SY, Chae KJ, Park HM

Purpose Identifying pretreatment interstitial lung abnormalities (ILAs) is important because of their predictive value for complications after lung cancer treatment. This study aimed to assess the predictive value of ILAs for...
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Histologic Changes in Non–Small Cell Lung Cancer under Various Treatments: A Comparison of Histology and Mutation Status in Serial Samples

Woo CG, Son SM, Lee HC, Han HS, Lee KH, Kim D, Kim EG, Lee OJ

Purpose Histologic change is a resistant mechanism in lung cancer. The most common histological change is the switch from adenocarcinoma (AdenoCa) to small cell carcinoma (SCC) against to tyrosine kinase inhibitors...
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Cost Utility Analysis of a Pilot Study for the Korean Lung Cancer Screening Project

Kim J, Cho B, Kim SH, Choi CM, Kim Y, Jo MW

Purpose The aim of this study was to evaluate the cost utility of a pilot study of Korean Lung Cancer Screening Project. Materials and Methods We constructed a Markov model consisting...
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Prognosis of Synchronous Double Primary Lung Cancer Based on Immunohistochemical Staining

Seok Y

Objective: This study evaluated the prognosis of strictly selected synchronous double primary lung cancer. Methods: The records of patients who underwent complete resection for synchronous double primary lung cancer were reviewed....
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Lung Cancer Screening With Low-dose Chest Computed Tomography: Experience From Radon-contaminated Regions in Kazakhstan

Panina A, Kaidarova D, Zholdybay Z, Ainakulova A, Amankulov J, Toleshbayev D, Zhakenova Z, Khozhayev A

Objectives: The aim of this study was to present the baseline results of a pilot project conducted to evaluate the effectiveness of lung cancer screening using low-dose chest computed tomography...
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Challenges in the Use of Targeted Therapies in Non–Small Cell Lung Cancer

Rivera-Concepcion J, Uprety D, Adjei AA

Precision oncology has fundamentally changed how we diagnose and treat cancer. In recent years, there has been a significant change in the management of patients with oncogene-addicted advanced-stage NSCLC. Increasing...
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A Comprehensive Analysis of 5-Year Outcomes in Patients with Cancer Admitted to Intensive Care Units

Hong Y, Kim WJ, Hong JY, Jeong Yj, Park J

Background: The aim of this study was to evaluate the long-term (5-year) clinical outcomes of patients who received intensive care unit (ICU) treatment using Korean nationwide data. Methods: All patients aged...
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The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced EGFR-Mutant Lung Adenocarcinoma

Huang YH, Hsu KH, Chin CS, Tseng JS, Yang TY, Chen KC, Su KY, Yu SL, Chen JJ, Chang GC

Purpose The aim of this study was to investigate the efficacy of various epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) plus bevacizumab in advanced EGFR-mutant lung adenocarcinoma patients. Materials and Methods From...
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Magnetic resonance imaging for lung cancer: a state-of-the-art review

Bak SH, Kim C, Kim CH, Ohno Y, Lee HY

Lung cancer is the leading cause of cancer-related deaths worldwide, and imaging techniques such as chest radiography, computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) play...
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Prognosis for Pneumonic-Type Invasive Mucinous Adenocarcinoma in a Single Lobe on CT: Is It Reasonable to Designate It as Clinical T3?

Kim W, Lee SM, Lee JB, Seo JB, Kim HK, Kim J, Lee HY

Objective: To compare pneumonic-type invasive mucinous adenocarcinoma (pIMA) confined to a single lobe with clinical T2, T3, and T4 stage lung cancer without pathological node metastasis regarding survival after curative...
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Primary Pulmonary Malignant Melanoma Presenting as Bilateral Multiple Subsolid Nodules: A Case Report

Soh EG, Rho JY, Jeong S, Kang SR, Choi KH

Primary pulmonary malignant melanoma is an extremely rare type of melanoma. The radiologic features of primary pulmonary malignant melanoma are nonspecific; however, it almost always presents as a well-demarcated round...
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Early Outcomes of Robotic Versus Video-Assisted Thoracoscopic Anatomical Resection for Lung Cancer

Park JH, Park S, Kang CH, Na BS, Bae SY, Na KJ, Lee HJ, Park IK, Kim YT

Background: We compared the safety and effectiveness of robotic anatomical resection and video-assisted thoracoscopic surgery (VATS). Methods: A retrospective analysis was conducted of the records of 4,283 patients, in whom an...
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Effects of Inhalation versus Total Intravenous Anesthesia on Postoperative Pulmonary Complications after Anatomic Pulmonary Resection

Lee S, Cho JS, Kim E, Kim Y, Lee J

Background: No consensus exists regarding whether volatile anesthetics are superior to intravenous anesthetics for reducing postoperative pulmonary complications (PPCs) in patients undergoing general anesthesia for surgery. Studies of this issue...
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Prognostic Impact of Postoperative Complications in High-Risk Operable Non-small Cell Lung Cancer

Lee S, Roknuggaman M, Son JA, Hyun S, Jung J, Haam S, Yu WS

Background: Patients with high-risk (HR) operable non-small cell lung cancer (NSCLC) may have unique prognostic factors. This study aimed to evaluate surgical outcomes in HR patients and to investigate prognostic...
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Adjuvant Chemotherapy in Patients with Node-Negative Non-Small Cell Lung Cancer with Satellite Pulmonary Nodules in the Same Lobe

Park J, Lee J, Jeon YJ, Shin S, Cho JH, Kim HK, Choi YS, Kim J, Zo JI, Shim YM

Background: According to the eighth TNM (tumor-node-metastasis) staging system, the presence of separate tumor nodules in the same lobe is designated as a T3 descriptor.However, it remains unclear whether adjuvant...
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Lung Cancer Screening with Low-Dose Chest Computed Tomography

Kim YW

Early detection and treatment is important to reduce mortality from lung cancer. Based on the positive results of lung cancer-related mortality reduction from large randomized trials of low-dose chest computed...
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Targeted Liquid Biopsy Using Irradiation to Facilitate the Release of Cell-Free DNA from a Spatially Aimed Tumor Tissue

Noh JM, Kim YJ, Lee HY, Choi C, Ahn WG, Lee T, Pyo H, Park JH, Park D, Park WY

Purpose We investigated the feasibility of using an anatomically localized, target-enriched liquid biopsy (TLB) in mouse models of lung cancer. Materials and Methods After irradiating xenograft mouse with human lung cancer...
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Occupational Exposure to Pesticides and Lung Cancer Risk: A Propensity Score Analyses

Kim B, Park EY, Kim J, Park E, Oh JK, Lim MK

Purpose Occupational exposure to pesticides is thought to be associated with lung cancer, but studies have yielded conflicting results. We performed a propensity score (PS) based analyses to evaluate the...
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Impact of Symptom Clusters on the Quality of Life in Lung Cancer Patients Undergoing Chemotherapy

Kim GD

Purpose: This study was to identify the impact of symptom clusters on the quality of life in lung cancer patients undergoing chemotherapy. Methods: Data were collected from 154 lung cancer...
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