- p53 Promotes Differentiation of Cardiomyocytes from hiPSC through Wnt Signaling-Mediated Mesendodermal Differentiation
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Liu Y, Zhang P, Huang W, Liu F, Long D, Peng W, Dang X, Zeng X, Zhou R
- KMID: 2522560
- Int J Stem Cells.
- 2021 Nov;14(4):410-422.
- doi: 10.15283/ijsc21051
Background and Objectives: Manipulating different signaling pathways via small molecules could efficiently induce cardiomyocytes from human induced pluripotent stem cells (hiPSC). However, the effect of transcription factors on the hiPSC-directed cardiomyocytes... -
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- The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC
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Liu F, Long D, Huang W, Peng W, Lan H, Zhou Y, Dang X, Zhou R
- KMID: 2532399
- Int J Stem Cells.
- 2022 Aug;15(3):247-257.
- doi: 10.15283/ijsc21148
Background and Objectives: Although human-induced pluripotent stem cells (hiPSC) can be efficiently differentiated into cardiomyocytes (CMs), the heterogeneity of the hiPSC-CMs hampers their applications in research and regenerative medicine. Retinoic... -
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