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Comparative Behavioral Correlation of High and Low-Performing Mice in the Forced Swim Test

Valencia S, Gonzales E, Adil KJ, Jeon SJ, Kwon KJ, Cho KS, Shin CY

Behavioral analysis in mice provided important contributions in helping understand and treat numerous neurobehavioral and neuropsychiatric disorders. The behavioral performance of animals and humans is widely different among individuals but...
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Reliability and validity of free software for the analysis of locomotor activity in mice

Hong YR, Moon E

BACKGROUND: Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field...
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Hangover relieving effect of Sanghwang mushroom mycelium cultured in germinated buckwheat

An YJ, Cho SM, Kim MS, Moon HH, Park DS, Jeon NG, Lee Y, Han CH

The present study was performed to evaluate the hangover relieving effect of germinated buckwheat (GB) and Sanghwang mushroom mycelium cultured in GB (SGB). Both GB and SGB showed 1,1-diphenyl-2-picrylhydrazyl radical...
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Hangover relieving effect of Sanghwang mushroom mycelium extract

Kim MS, An YJ, Lee JC, Park GR, Park DS, Jeon NG, Lee Y, Han CH

This study was conducted to evaluate the hangover relieving effect of Sanghwang mushroom mycelium extract (SME). The extract showed 1,1-diphenyl-2-picrylhydrazyl radical scavenging effect in a concentration-dependent manner and high antioxidant...
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Effect of medicinal plant extract for hangover relief

Hyun CS, Park G, Oh YM, Lee Y, Han CH

The present study was performed to evaluate the effect of medicinal plant extract on relieving hangovers in mice administered alcohol. The animals were divided into three groups. Each group was...
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Delay in the Recovery of Normal Sleep-Wake Cycle after Disruption of the Light-Dark Cycle in Mice: A Bipolar Disorder-Prone Animal Model?

Jung SH, Park JM, Moon E, Chung YI, Lee BD, Lee YM, Kim JH, Kim SY, Jeong HJ

OBJECTIVE: Disruption of the circadian rhythm is known as a provoking factor for manic episodes. Individual differences exist in the recovery rate from disruption in the general population. To develop...
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Effects of Chronic Mild Stress in Female Bax Inhibitor-1-Gene Knockout Mice

Sui ZY, Chae HJ, Huang GB, Zhao T, Shrestha Muna S, Chung YC

OBJECTIVE: The anti-apoptotic protein Bax inhibitor-1 (BI-1) is a regulator of apoptosis linked to endoplasmic reticulum (ER) stress, and BI-1-/- mice exhibit increased sensitivity to tissue damage. The purpose of...
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Exposure to Extremely Low Frequency Magnetic Fields Induces Fos-Related Antigen-Immunoreactivity Via Activation of Dopaminergic D1 Receptor

Shin EJ, Nguyen XK, Nguyen TT, Pham DT, Kim HC

We previously demonstrated that repeated exposure to extremely low frequency magnetic fields (ELF-MF) increases locomotor activity via stimulation of dopaminergic D1 receptor (J. Pharmacol. Sci., 2007;105:367-371). Since it has been...
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Implication of Glutamatergic Mechanism for the Behavioral Changes Resulting from Early Maternal Separation during the Development in Juvenile Rats

Park SH, Chung YI

  • KMID: 2287383
  • Korean J Psychopharmacol.
  • 2010 Apr;21(2):71-77.
OBJECTIVE: Early maternal separation (EMS) during the development has been known to influence the alteration of behavior in adulthood. Nitric oxide (NO) may have been implicated to play a crucial...
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Effects of Prenatal Exposure to Nitric Oxide Synthase Inhibitor on Behavioral Changes in Forced Swimming Test in Postnatal Rats

Kim GJ, Park SH, Chung YI

  • KMID: 2341339
  • J Korean Neuropsychiatr Assoc.
  • 2007 Sep;46(5):512-517.
OBJECTIVES: It has been demonstrated that nitric oxide (NO) serves as an inter- and intra-cellular messenger in the brain. NO has been implicated in the regulation of monoaminergic neurotransmission and...
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Behavioral Testing for Therapeutic Outcome Measurements in an Animal Model of Huntington's Disease

Cho SR, Park ES, Kim HO, Kim DG, Park CI

  • KMID: 2394172
  • J Korean Acad Rehabil Med.
  • 2007 Oct;31(5):503-511.
OBJECTIVE: To investigate which outcome measurements are useful for detecting functional changes after therapeutic approach to delayed motor impairment in an animal model of Huntington's disease (HD). METHOD: R6/2 transgenic...
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Effects of exposure conditions to footshocks early in life on spontaneous locomotor activity at maturity in rats

Kim DG, Lee S, Lim JS

Both genetic and environmental factors are involved in establishing a behavior. An animal study was done to determine the characteristics of interaction between genetic (nature) and environmental (nurture)...
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