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A study on changes of coagulation inhibitors and fibrinolysis inhibitors in patients with liver cirrhosis and hepatoma

Park CJ, Cho HI, Kim SI

The authors conducted an investigation focusing mainly on the activities of the inhibitory factors of the coagulation and fibrinolysis processes in 35 normal adults and 72 liver cirrhosis and/or hepatoma...
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Growth Differentiation Factor 15 Predicts Chronic Liver Disease Severity

Lee ES, Kim SH, Kim HJ, Kim KH, Lee BS, Ku BJ

BACKGROUND/AIMS: Growth differentiation factor 15 (GDF-15) belongs to the transforming growth factor-β superfamily. GDF-15 is emerging as a biomarker for several diseases. The aim of this study was to determine...
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Clinical Significance of Serum CA 125 in Patients with Chronic Liver Diseases

Kim YS, Kim DY, Ryu KH, Song JH, Kim MS, Jung HS, Park JY, Jung HK, Yoo K, Moon IH, Baek JY

  • KMID: 1112192
  • Korean J Gastroenterol.
  • 2003 Nov;42(5):409-414.
BACKGROUND/AIMS: The clinical significance of serum CA 125 levels in patients with chronic liver disease has not been widely appreciated in relation to the severity of the disease. We...
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Clinical Implications of the Serum Apelin Level on Portal Hypertension and Prognosis of Liver Cirrhosis

Lim YL, Choi E, Jang YO, Cho YZ, Kang YS, Baik SK, Kwon SO, Kim MY

BACKGROUND/AIMS: Levels of serum apelin (s-apelin), an endogenous ligand for angiotensin-like receptor 1, have been shown to be related to hepatic fibrosis and hemodynamic abnormalities in preclinical studies. We investigated...
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Potential Serum Markers for Monitoring the Progression of Hepatitis B Virus-Associated Chronic Hepatic Lesions to Liver Cirrhosis

Wu C, Liu L, Zhao P, Tang D, Yao D, Zhu L, Wang Z

BACKGROUND/AIMS: To screen for serum protein/peptide biomarkers of hepatitis B virus (HBV)-associated chronic hepatic lesions in an attempt to profile the progression of HBV-associated chronic hepatic lesions using surface-enhanced laser...
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N-terminal Pro B-type Natriuretic Peptide and the Evaluation of Cardiac Dysfunction and Severity of Disease in Cirrhotic Patients

Woo JJ, Koh YY, Kim HJ, Chung JW, Chang KS, Hong SP

PURPOSE: Cardiac dysfunction and hyperdynamic systemic circulation may be present in patients with cirrhosis. The purpose of this study was to identify relations between plasma levels of N-terminal-proBNP (NT-proBNP), reflecting...
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U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis

Benz F, Roderburg , Vargas Cardenas D, Vucur M, Gautheron , Koch A, Zimmermann H, Janssen J, Nieuwenhuijsen L, Luedde M, Frey N, Tacke F, Trautwein , Luedde T

  • KMID: 2154261
  • Exp Mol Med.
  • 2013 Sep;45(9):e42.
MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of...
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Association of Helicobacter pylori with Elevated Blood Ammonia Levels in Cirrhotic Patients: A Meta-Analysis

Jiang HX, Qin SY, Min ZG, Xie MZ, Lin T, Hu BL, Guo XY

PURPOSE: The association between Helicobacter pylori (H. pylori) and blood ammonia levels in cirrhotic patients is controversial. We aimed to clarify this controvercy by performing a meta-analysis of published studies. MATERIALS...
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