- Association Between Polymorphisms of Ethanol-Metabolizing Enzymes and Susceptibility to Alcoholic Cirrhosis in a Korean Male Population
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Lee HC, Lee HS, Jung SH, Yi SY, Jung HK, Yoon JH, Kim CY
- KMID: 648356
- J Korean Med Sci.
- 2001 Dec;16(6):745-750.
- doi: 10.3346/jkms.2001.16.6.745
Alcohol is oxidized to acetaldehyde by alcohol dehydrogenase (ADH) and cytochrome P-4502E1 (CYP2E1), and then to acetate by aldehyde dehydrogenase (ALDH). Polymorphisms of these ethanol-metabolizing enzymes may be associated with... -
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- Effects of Genetic Polymorphisms of Ethanol-Metabolizing Enzymes on Alcohol Drinking Behaviors
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Kee JY, Kim MO, You IY, Chai JY, Hong ES, An SC, Kim H, Park SM, Youn SJ, Chae HB
- KMID: 863142
- Korean J Hepatol.
- 2003 Jun;9(2):89-97.
BACKGROUND/AIMS: Genetic variations of ethanol-metabolizing enzymes can affect alcohol drinking behavior. The aims of this study were to investigate and compare the distributions of these genetic polymorphisms between a... -
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- The Enhancing Effect of Ethanol on the Development of Glutatione S-Transferase Placental Form-Positive Foci Induced by Diethylnitrosamine in F344 Rat
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Cho KJ, Myung NH, Jang JJ
- KMID: 1421473
- J Korean Med Sci.
- 1990 Mar;5(1):13-17.
- doi: 10.3346/jkms.1990.5.1.13
The effects of ethyl alcohol and pig serum administration on the development of preneoplastic hepatic enzyme-altered foci were examined in an in vivo mid-term assay system. Rats were initially given... -
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