- Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats
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Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z
- KMID: 1120195
- Yonsei Med J.
- 2012 Mar;53(2):294-303.
- doi: 10.3349/ymj.2012.53.2.294
PURPOSE: Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of... -
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- Repeated dose toxicity of alfa-cypermethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
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- Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism
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Yoon MC, Jeong SH, Nicol CJ, Lee HH, Han MY, Kim JJ, Seo YJ, Ryu CY, Oh GT
- KMID: 1121103
- Exp Mol Med.
- 2002 Dec;34(6):481-488.
To determine whether the PPARalpha agonist fenofibrate regulates obesity and lipid metabolism with sexual dimorphism, we examined the effects of fenofibrate on body weight, white adipose tissue (WAT) mass,... -
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- Inhibitory Effect of Angiotensin Blockade on Hepatic Fibrosis in Common Bile Duct-ligated Rats
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Park DH, Baik SK, Choi YH, Kim MY, Rhim DW, Kim JW, Kwon SO, Cho MY, Kim CH, Ahn SC
- KMID: 760706
- Korean J Hepatol.
- 2007 Mar;13(1):61-69.
BACKGROUNDS AND AIMS: Angiotensin receptors are found on hepatic stellate cells, which participate in hepatic fibrosis. Therefore, it is presumed that angiotensin has a role in hepatic fibrosis. The... -
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- Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy
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Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG
- KMID: 1123370
- Exp Mol Med.
- 2011 Oct;43(10):580-586.
- doi: 10.3858/emm.2011.43.10.065
Malignant glioma is the most frequent type in brain tumors. The prognosis of this tumor has not been significantly improved for the past decades and the average survival of patients... -
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- Suppressive Effects of Antioxidant DA-9601 on Hepatic Fibrosis in Rats
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Cheong JY, Oh TY, Lee KM, Kim DH, Ahn BO, Kim WB, Kim YB, Yoo BM, Hahm KB, Kim JH, Cho SW
- KMID: 863119
- Korean J Hepatol.
- 2002 Dec;8(4):436-447.
BACKGROUND/AIMS: Oxidative stress is one of the important underlying mechanisms of hepatic fibrosis. DA-9601, the ethanol extracts of Artemisia asiatica, has been reported to possess strong antioxidative and cytoprotective... -
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- Gene transfer using liposome-complexed adenovirus seems to overcome limitations due to coxsackievirus and adenovirus receptor-deficiency of cancer cells, both in vitro and in vivo
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Han SY, Lee YJ, Jung HI, Lee SW, Lim SJ, Hong SH, Jeong JS
- KMID: 1094122
- Exp Mol Med.
- 2008 Aug;40(4):427-434.
- doi: 10.3858/emm.2008.40.4.427
Use of adenoviruses as vehicle for gene therapy requires that target cells express appropriate receptors such as coxsakievirus and adenovirus receptor (CAR). We show here that CAR-deficiency in cancer cells,... -
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