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Clinical application of stem cells in liver diseases

Bae SH

Most liver diseases lead to hepatic dysfunction with organ failure. Liver transplantation is the best curative therapy, but it has some limitations such as donor shortage, possibility of rejection, and...
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Biology of Cholangiocytes: From Bench to Bedside

Yoo KS, Lim WT, Choi HS

Cholangiocytes, the lining epithelial cells in bile ducts, are an important subset of liver cells. They are activated by endogenous and exogenous stimuli and are involved in the modification of...
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The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration

Lua I, Asahina K

Mesothelial cells (MCs) cover the surface of visceral organs and the parietal walls of cavities, and they synthesize lubricating fluids to create a slippery surface that facilitates movement between organs...
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Parenchymal and Nonparenchymal Cellular Responses in Human Hepatic Regeneration

Yoon GS, Suriawinata A, Thung SN, Yu E

To characterize cellular responses during hepatic regeneration, we examined 13 explant livers and 5 liver allografts by immunohistochemistry for cytokeratin 7, HepPar1, CD68, alpha-smooth muscle actin (alpha-SMA) and proliferating cell...
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Cell cycle protein profile of the hepatic stellate cells (HSCs) in dimethylnitrosamine-induced rat hepatic fibrosis

Kim MR, Kim HS, Lee MS, Lee MJ, Jang JJ

  • KMID: 1093468
  • Exp Mol Med.
  • 2005 Aug;37(4):335-342.
Cell cycle regulating proteins are known to have close relation with the proliferation of the mammalian cells. In injured liver, the number of HSCs is increased from proliferation. However, the...
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