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Artificial Liver Assist Devices

Choi WC

  • KMID: 2083051
  • Korean J Hepatol.
  • 2000 Dec;6(4):411-420.
No abstract availalbe.
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Artificial Liver Devices and Bioartificial Liver Systems: Current Status

Kwon CH, Lee SK, Park JK, Lee DH, Lee JH

Acute liver failure is a rapidly progressive disease of the liver associated with high morbidity and mortality without liver transplantation. Although good survival after transplantation can be achieved, due to...
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Artificial liver composed of liver slice culture system

Park SS, Han JJ

  • KMID: 1530116
  • Korean J Anat.
  • 1998 Jun;31(3):483-491.
Acute hepatic failure is one of the most fatal in clinical medicine, as it can be associated with a mortality rate of 80~ 90%. For the treatment of acute hepatic...
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Hybrid Bioartificial Liver

Kim YI

  • KMID: 1536116
  • J Korean Med Assoc.
  • 1997 Mar;40(3):365-371.
No abstract available.
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The Difference of Nodule Detection Rates in the Liver According to the Pitch and Slice Thickness in Spiral CT: Experimental Study by Using Artificial Liver Phantom

Lee MJ, Seol HY, Kim JH, Lee SC, Chung KB

PURPOSE: To determine optimal pitch and slice thickness when detecting small hepatoma by spiral CT. MATERIAL AND METHODS: Three types of artificial liver phantom of 45, 65, and 85 HU...
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Successful salvage treatment of acute graft-versus-host disease after liver transplantation by withdrawal of immunosuppression: a case report

Qiu W, Lv GY, Jiang C, Zhang P, Sun XD, Shi XJ, Liu XY, Wang GY

Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported...
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Cell Sources, Liver Support Systems and Liver Tissue Engineering: Alternatives to Liver Transplantation

Lee SY, Kim HJ, Choi D

The liver is the largest organ in the body; it has a complex architecture, wide range of functions and unique regenerative capacity. The growing incidence of liver diseases worldwide requires...
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Rat-Hepatocyte Culture and Differentiation in Hormone-Supplemented Media

Kim HC, Kim JS, Jung SE, Lee KU

  • KMID: 2095549
  • J Korean Surg Soc.
  • 1999 Jan;56(1):20-26.
BACKGROUND: Severe liver disease is very often life threatening and dramatically diminishes the quality of life. An effective artificial liver support system should be capable of sustaining patients with severe...
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Hepatocyte Isolation, Culture, and Its Clinical Applications

Lee DH, Lee KW

Hepatocytes, parenchymal cells of the liver, are specially differentiated cells to perform most of the body metabolisms. Many clinicians are interested in utilizing hepatocytes as cell therapeutics. A great number...
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Nonsurgical Management of Fulmninant Hepatic Failure: Hepatocyte transplantation and bioartificial liver

Kim BH

  • KMID: 2241340
  • Korean J Hepatol.
  • 1996 Sep;2(2):116-128.
BACKGROUND: Fulminant hepatic failure is a devastating process associated with high mortality, but no sequele after recovep. At the moment, there are no specific therapeutic modalities except for the orthotopic...
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Bioartificial Liver System using a Fluidized-Bed Bioreactor

Hwang YJ, Kim JY, Chang SK, Kim SG, Kim YI, Hwang JH

  • KMID: 2244205
  • Korean J Hepatobiliary Pancreat Surg.
  • 2008 Mar;12(1):41-45.
PURPOSE: Acute fulminant hepatic failure (FHF) is associated with high mortality. Recent studies have shown that a liver support system based on viable hepatocytes can prolong life in animal models...
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Tissue engineering in the twenty-first century

Terada S, Sato M, Sevy A, Vacanti JP

In the 20th century, free tissue transfers have been successfully introduced using microvascular anastomosis techniques. Transplants not only include whole organs such as the kidney, liver and lung, but also...
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Isolation and Culture of Pig Hepatocyte in Large Scale for the Application of Bioartificial Liver System

Chung YJ, Lee HJ, Koh YT, Kim SB, Kim SH, Choi SH, Yi NJ, Chang SH, Yang EL, Suh KS, Lee YS, Lee KU

  • KMID: 863094
  • Korean J Hepatol.
  • 2002 Sep;8(3):249-255.
BACKGROUND/AIMS: Acute hepatic failure is a serious problem. Its mortality reaches up to 80%. Only liver transplantation has been accepted as a definite treatment for patients with hepatic failure...
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Three-dimensional (3D) printing of mouse primary hepatocytes to generate 3D hepatic structure

Kim Y, Kang K, Jeong J, Paik SS, Kim JS, Park SA, Kim WD, Park J, Choi D

PURPOSE: The major problem in producing artificial livers is that primary hepatocytes cannot be cultured for many days. Recently, 3-dimensional (3D) printing technology draws attention and this technology regarded as...
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Optimal Number of Hepatocytes per Microcarrier in Spheroid Culture using Cytodex 3 Microcarrier

Shin WY, Lee KU, Lee HW, Cho EH, Yi NJ, Suh KS

  • KMID: 2211102
  • J Korean Surg Soc.
  • 2007 Sep;73(3):235-241.
PURPOSE: The mass cultivation of functional hepatocytes is a key factor of a bioartificial liver. Combining spheroid and microcarrier cultures has been applied for enhancing the cell viability and metabolic...
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The Viability and Function of Cryopreserved Hepatocyte Spheroids with Different Cryopreservation Solutions

Park JB, Lee KW, Kim SJ, Lee SK, Park JH, Woo DH, Joh JW

  • KMID: 2004509
  • J Korean Surg Soc.
  • 2003 Sep;65(3):181-189.
PURPOSE: The bioartificial liver via extracorporeal circulation and the hepatocyte transplantation have been studied due to donor organ shortage. Hepatocyte spheroids, which are tightly packed multicellular aggregates, showed enhanced liver...
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Augmentation of Butyrate-induced Differentiation of Human Hepatocyte for the Development of an Efficient Bioartificial Liver

Kim YJ, Lee HS

  • KMID: 2084972
  • Korean J Gastroenterol.
  • 2001 Jan;37(1):35-42.
BACKGROUND/AIMS: We examined whether we could produce hepatocytes with further differentiated functions by promoting G1-S transition of the cell cycle in a butyrate-treated human hepatocyte cell line that we have...
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Cost-Identification Analysis between Amphotericin B deoxycholate and Intravenous Itraconazole in the Empirical Treatment of Febrile Neutropenic Patients:Preliminary Report

Lee DG, Song YG, Yoo JH, Choi SM, Choi JH, Park SH, Shin WS

  • KMID: 2285111
  • Infect Chemother.
  • 2004 Oct;36(5):304-310.
BACKGROUND: The increasing incidence of systemic fungal infections and the rising medical cost have focused the need to determine the economic issues of antifungal agents. Nevertheless there have been only...
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Freezing and Thawing Conditions of Rat Hepatocytes

Hwang SG, Jung EM, Oh SW, Kwon CI, Kim KC, Hong SP, Park PW, Rim KS

  • KMID: 1890007
  • Korean J Hepatol.
  • 2001 Sep;7(3):308-314.
BACKGROUND/AIMS: During cryopreservation of hepatocytes, a dramatic loss in cell number, viability and differentiated cell function is usually inevitable because hepatocytes are very sensitive to stress during freezing and thawing....
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