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High-Density Lipoprotein, Lecithin: Cholesterol Acyltransferase, and Atherosclerosis

Ossoli A, Pavanello , Calabresi

Epidemiological data clearly show the existence of a strong inverse correlation between plasma high-density lipoprotein cholesterol (HDL-C) concentrations and the incidence of coronary heart disease. This relation is explained by...
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The Causes and Consequences of Low Levels of High Density Lipoproteins in Patients with Diabetes

Barter PJ

Type 2 diabetes is commonly accompanied by a low level of high density lipoprotein cholesterol (HDL-C) that contributes to the increased cardiovascular risk associated with this condition. Given that HDLs...
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High Density Lipoprotein: A Therapeutic Target in Type 2 Diabetes

Barter PJ

High density lipoproteins (HDLs) have a number of properties that have the potential to inhibit the development of atherosclerosis and thus reduce the risk of having a cardiovascular event. These...
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Tumor Necrosis Factor-Alpha Induced VCAM-l Expression is Inhibited by High Density Lipoprotein in Human Astroglioma Cells

Wagley Y, Oh JW

  • KMID: 2283439
  • Korean J Phys Anthropol.
  • 2008 Sep;21(3):225-233.
Astrocytes, the major glial cells in the central nervous system (CNS), can express vascular cell adhesion molecule-1(VCAM-1) in response to cytokines, such as TNF-alpha. In CNS, an increased VCAM-1 expression...
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Antioxidative Activity after Rosuvastatin Treatment in Patients with Stable Ischemic Heart Disease and Decreased High Density Lipoprotein Cholesterol

Park DS, Yun KH, Park HY, Rhee SJ, Kim NH, Oh SK, Jeong JW

BACKGROUND AND OBJECTIVES: The clinical significance of statin-induced high-density lipoprotein cholesterol (HDL-C) changes is not well known. We investigated whether rosuvastatin-induced HDL-C changes can influence the anti-oxidative action of high-density...
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A Case of Familial Hypercholesterolemia with Diabetes Mellitus

Sohn YK, Chang KY, Lee KH, Tockgo YC

  • KMID: 1554070
  • J Korean Pediatr Soc.
  • 1997 Jun;40(6):862-866.
Familial Hypercholesterolemia is the most common hyperlipoproteinemia during the childhood, which occurs from the mutation of genes that regulates low-density lipoproteins (LDL), and is classified into two types, the homozygote...
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Decrease of Proapolipoprotein AI was Associated with Poor Prognosis in Patients with Septic Shock

Kwon WY, Suh GJ, Jo YH, Kim K

  • KMID: 2332930
  • J Korean Soc Emerg Med.
  • 2011 Jun;22(3):231-241.
PURPOSE: Proteomics is a peptide screening approach to identify proteins related to physiological and pathological changes. Our objective was to analyze changes in serum proteome profiles in patients suffering from...
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Change of plasma lipoproteins by heparin-released lipoprotein lipase

Yang JY, Kim TK, Koo BS, Park BH, Park JW

  • KMID: 1029932
  • Exp Mol Med.
  • 1999 Jun;31(2):60-64.
Lipoprotein lipase (LPL) is known to be attached to the luminal surface of vascular endothelial cells in a complex with membrane-bound heparan sulfate, and released into blood stream by heparin. LPL that...
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Triglycerides to High-Density Lipoprotein Cholesterol Ratio Can Predict Impaired Glucose Tolerance in Young Women with Polycystic Ovary Syndrome

Song DK, Lee H, Sung YA, Oh JY

PURPOSE: The triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio could be related to insulin resistance (IR). We previously reported that Korean women with polycystic ovary syndrome (PCOS) had a high...
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Risk Factors for Progression to Postpartum Diabetes Mellitus and Perinatal Complications in Women with Gestational Diabetes Mellitus

Kim SJ, Chun H, Jang EH, Lee JS, Kim M, Baek KH, Song KH, Kwon HS

BACKGROUND: Gestational diabetes mellitus (GDM) is a hyperglycemic condition caused by increased insulin resistance and impaired insulin secretion during pregnancy. It is known to be temporary, but it can cause...
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An ethanolic extract of Angelica gigas improves atherosclerosis by inhibiting vascular smooth muscle cell proliferation

Jang JY, Kim J, Cai J, Kim Y, Shin K, Kim TS, Lee SP, Park SK, Choi EK, Kim YB

The effects of an ethanolic extract of Angelica gigas (EAG) on the vascular smooth muscle cell (VSMC) proliferation and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis were investigated. Rat aortic VSMCs were...
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A common mutation in cholesteryl ester transfer protein gene and plasma HDL cholesterol level before and after hormone replacement therapy in Korean postmenopausal women

Choi HS, Park JB, Han KO, Yim CH, Jung HY, Jang HC, Yoon HK, Cho DH, Shin HH, Han IK

  • KMID: 1129106
  • Korean J Intern Med.
  • 2002 Jun;17(2):83-87.
BACKGROUND: Plasma cholesteryl ester transfer protein (CETP) functions to transfer cholesteryl ester from HDL to triglyceride-rich lipoproteins and regulates plasma HDL cholesterol level. A common mutation, the exon 15 A...
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Associations between Oxidized LDL to LDL Ratio, HDL and Vascular Calcification in the Feet of Hemodialysis Patients

An WS, Kim SE, Kim KH, Bae HR, Rha SH

Cardiovascular mortality is associated with vascular calcification (VC) in hemodialysis (HD) patients. The present study was designed to find factors related with medial artery calcification on the plain radiography of...
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Influence of menopause on high density lipoprotein-cholesterol and lipids

Kim CJ, Kim TH, Ryu WS, Ryoo UH

It has been generally accepted that high density lipoprotein cholesterol (HDL-C) level decreases with menopause in women. However, recent reports show different results. There is very little data concerning perimenopausal...
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The Pattern of Weight Gain and Change of Peripheral Serum Lipid Profiles in Idiopathic Epileptic Children Treated with Valproate

Kim IC, Kim ES, Bae EJ, Park WI, Lee HG, Lee KJ

  • KMID: 2007346
  • J Korean Child Neurol Soc.
  • 2002 May;10(1):81-86.
PURPOSE: This study was performed to investigate the change of weight and body composition, and lipid profiles in the idiopathic epileptic children treated with valproate. METHODS: We measured the weight, height,...
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Comparison of Cardiovascular Risk Factors between Normotension and Prehypertension

Nah EH, Kim HC

BACKGROUND: The individuals with prehypertension are known to progress to hypertension, one of the risk factors of cardiovascular disease, more readily than the group of normal blood pressure. This...
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Inter-relationships between arteriosclerotic risk factors: a meta-analysis

Oh HS, Seo WS

This study was performed to clarify the overall inter-relationships between the arteriosclerotic risk factors, including smoking, alcoholic consumption, obesity, serum cholesterol and triglyceride levels, high density lipoprotein, and systolic and...
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A reconstituted HDL containing V156K or R173C apoA-I exhibited anti-inflammatory activity in apo-E deficient mice and showed resistance to myeloperoxidase-mediated oxidation

Cho KH, Kim JR

It has been hypothesized that blood infusion of reconstituted HDL (rHDL) is a possible therapeutic strategy for the treatment of coronary artery disese. To compare short-term anti-inflammatory activity of wildtype...
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Monoclonal antibody production and characterization for the measurement of plasma high density lipoprotein

Lee SH, Cho MH

We prepared two monoclonal antibodies-A-I30 and A-I4 to HDL apo A-I-with the ultimate goals of expressing and overproducing the valuable immunodiagnostic single chain Fv by phage display libraries in E,...
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The Impact of CDH13 Polymorphism and Statin Administration on TG/HDL Ratio in Cardiovascular Patients

Choi JR, Jang Y, Kim Yoon S, Park JK, Sorn SR, Park MY, Lee M

PURPOSE: Adiponectin is expressed in adipose tissue, and is affected by smoking, obesity, and genetic factors, such as CDH13 polymorphism, contributing to the development of coronary vascular diseases (CVDs). MATERIALS AND...
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