- Quantifications of Lipid Kinetics In Vivo Using Stable Isotope Tracer Methodology
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Kim IY, Park S, Jang J, Wolfe RR
- KMID: 2470804
- J Lipid Atheroscler.
- 2020 Jan;9(1):110-123.
- doi: 10.12997/jla.2020.9.1.110
Like other bodily materials, lipids such as plasma triacylglycerol, cholesterols, and free fatty acids are in a dynamic state of constant turnover (i.e., synthesis, breakdown, oxidation, and/or conversion to other... -
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- CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction
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Glatz JF, Luiken JJ, Nabben M
- KMID: 2470801
- J Lipid Atheroscler.
- 2020 Jan;9(1):66-78.
- doi: 10.12997/jla.2020.9.1.66
The heart faces the challenge of adjusting the rate of fatty acid uptake to match myocardial demand for energy provision at any given moment, avoiding both too low uptake rates,... -
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- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
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Wang LY, Wu J, Gao YF, Lin DM, Ma J
- KMID: 2466566
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):19-26.
- doi: 10.4196/kjpp.2020.24.1.19
Medium- and long-chain triglyceride (MCT/LCT) propofol is widely used as an intravenous anesthetic, especially in the intensive care unit. The present study aimed to assess whether MCT/LCT propofol is safe... -
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- Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats
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Kim M, Kim TW, Kim CJ, Shin MS, Hong M, Park HS, Park SS
- KMID: 2467318
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S102-S110.
- doi: 10.5213/inj.1938216.108
PURPOSE: Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis... -
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- Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial
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Eshghi F, Bakhshimoghaddam F, Rasmi Y, Alizadeh M
- KMID: 2461099
- Clin Nutr Res.
- 2019 Oct;8(4):318-328.
- doi: 10.7762/cnr.2019.8.4.318
Obesity is a substantial public health challenge across the globe. The use of resistant starch has been proposed as a probable management strategy for complications of obesity. We investigated the... -
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- Genetically Mediated Lipid Metabolism and Risk of Insulin Resistance: Insights from Mendelian Randomization Studies
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Bu SY
- KMID: 2458378
- J Lipid Atheroscler.
- 2019 Sep;8(2):132-143.
- doi: 10.12997/jla.2019.8.2.132
Dysregulated lipid metabolism, characterized by higher levels of circulating triglycerides, higher levels of small, low density lipoprotein, and accumulation of intracellular lipids, is linked to insulin resistance and related complications... -
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- Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model
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Ayyappan J, lizardo K, Wang S, Yurkow E, Nagajyothi JF
- KMID: 2455094
- Biomol Ther.
- 2019 Jul;27(4):386-394.
- doi: 10.4062/biomolther.2018.193
Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM)... -
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- Free fatty acid-induced histone acetyltransferase activity accelerates lipid accumulation in HepG2 cells
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Chung S, Hwang JT, Park JH, Choi HK
- KMID: 2453283
- Nutr Res Pract.
- 2019 Jun;13(3):196-204.
- doi: 10.4162/nrp.2019.13.3.196
BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disease triggered by epigenetic alterations, including lysine acetylation at histone or non-histone proteins, affecting the stability or transcription of lipogenic... -
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- Effect of Sulgidduk containing pine needle juice on lipid metabolism in high fat-cholesterol diet induced dyslipidemic rats
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Lee Y, Park JH, Park E
- KMID: 2466678
- J Nutr Health.
- 2019 Feb;52(1):6-16.
- doi: 10.4163/jnh.2019.52.1.6
PURPOSE: Dyslipidemia is a major risk factor for cardiovascular disease. Pine needles (Pinus densiflora seib et Zucc) are a traditional medicine used to treat dyslipidemia in clinical settings. This study... -
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- Neurobiological understanding of suicide
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Kim S, Lee KU
- KMID: 2438368
- J Korean Med Assoc.
- 2019 Feb;62(2):85-92.
- doi: 10.5124/jkma.2019.62.2.85
Suicide is a complex phenomenon resulting from interactions between individual vulnerabilities and socio-environmental factors. The current review primarily focuses on research into the serotonin system, hypothalamic-pituitary-adrenal axis, neurotrophic factors, lipid... -
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- Age of Postmenopause Women: Effect of Soy Isoflavone in Lipoprotein and Inflammation Markers
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Barrasa GR, González Cañete N, Boasi LE
- KMID: 2455891
- J Menopausal Med.
- 2018 Dec;24(3):176-182.
- doi: 10.6118/jmm.2018.24.3.176
OBJECTIVES: Menopause is associated with adverse metabolic changes in plasma lipoprotein and inflammation markers. Estrogens have beneficial effects on lipid metabolism and inflammation. Isoflavones (ISO) have structurally similar to estradiol.... -
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- The antioxidant activity of steamed ginger and its protective effects on obesity induced by high-fat diet in C57BL/6J mice
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Kim HJ, Kim B, Mun EG, Jeong SY, Cha YS
- KMID: 2448695
- Nutr Res Pract.
- 2018 Dec;12(6):503-511.
- doi: 10.4162/nrp.2018.12.6.503
BACKGROUND/OBJECTIVES: Ginger, a root vegetable, is known to have antioxidant and antiobesity effects. Preparation, such as by steaming, can affect the chemical composition of prepared root vegetables or herbs and... -
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- Red pepper seed water extract inhibits preadipocyte differentiation and induces mature adipocyte apoptosis in 3T3-L1 cells
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Kim HJ, You MK, Lee YH, Kim HJ, Adhikari D, Kim HA
- KMID: 2448694
- Nutr Res Pract.
- 2018 Dec;12(6):494-502.
- doi: 10.4162/nrp.2018.12.6.494
BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the... -
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- Anti-inflammatory effects of Agar free-Gelidium amansii (GA) extracts in high-fat diet-induced obese mice
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Lee Y, Oh H, Lee M
- KMID: 2448692
- Nutr Res Pract.
- 2018 Dec;12(6):479-485.
- doi: 10.4162/nrp.2018.12.6.479
BACKGROUND/OBJECTIVES: Gelidium amansii (GA) contains plenty of agars and various biological substances, which make them a popular functional food to control body weight in previous studies. Unlike previous studies focused... -
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- The Expression of Adipophilin Is Frequently Found in Solid Subtype Adenocarcinoma and Is Associated with Adverse Outcomes in Lung Adenocarcinoma
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Shin SA, Na HY, Choe JY, Chung D, Park M, Oh S, Kim JE
- KMID: 2427517
- J Pathol Transl Med.
- 2018 Nov;52(6):357-362.
- doi: 10.4132/jptm.2018.09.13
BACKGROUND: The up-regulation of the lipogenic pathway has been reported in many types of malignant tumors. However, its pathogenic role or clinical significance is not fully understood. The objective of... -
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- Distinct Ultradian Rhythms in Plasma Clusterin Concentrations in Lean and Obese Korean Subjects
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Choi JH, Jeong E, Youn BS, Kim MS
- KMID: 2420493
- Endocrinol Metab.
- 2018 Jun;33(2):245-251.
- doi: 10.3803/EnM.2018.33.2.245
BACKGROUND: Blood levels of many hormones show rhythmic fluctuations with variable duration of cycles. Clusterin/apolipoprotein J is a glycoprotein which is highly expressed in the plasma and has modulatory roles... -
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- Channel Function of TRPML1 Prompts Lipolysis in Mature Adipocytes
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Kim MS, Kim MS
- KMID: 2437481
- Int J Oral Biol.
- 2018 Mar;43(1):23-27.
- doi: 10.11620/IJOB.2018.43.1.023
Increased intracellular levels of Ca²⺠are generally thought to negatively regulate lipolysis in mature adipocytes, whereas store-operated Ca²⺠entry was recently reported to facilitate lipolysis and attenuate lipotoxicity by inducing... -
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- Rapid Changes in Serum Lipid Profiles during Combination Therapy with Daclatasvir and Asunaprevir in Patients Infected with Hepatitis C Virus Genotype 1b
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Chida T, Kawata K, Ohta K, Matsunaga , Ito J, Shimoyama , Yamazaki S, Noritake H, Suzuki T, Suda T, Kobayashi
- KMID: 2429075
- Gut Liver.
- 2018 Mar;12(2):201-207.
- doi: 10.5009/gnl17179
BACKGROUND/AIMS: Changes in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years. However, the clinical aspects of disturbed lipid... -
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- Serum Betatrophin Concentrations and the Risk of Incident Diabetes: A Nested Case-Control Study from Chungju Metabolic Disease Cohort
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Lee SH, Rhee M, Kwon HS, Park YM, Yoon KH
- KMID: 2409186
- Diabetes Metab J.
- 2018 Feb;42(1):53-62.
- doi: 10.4093/dmj.2018.42.1.53
BACKGROUND: Betatrophin is a newly identified hormone derived from the liver and adipose tissue, which has been suggested to regulate glucose and lipid metabolism. Circulating levels of betatrophin are altered... -
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- PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis
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Yang X, Fu Y, Hu F, Luo X, Hu J, Wang G
- KMID: 2438361
- Exp Mol Med.
- 2018 Jan;50(1):e431.
- doi: 10.1038/emm.2017.243
Phosphatidylinositol 3-kinase (PI3K) signaling plays an important role in the regulation of cellular lipid metabolism and non-alcoholic fatty liver disease (NAFLD). However, little is known about the role of the... -
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