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PNPLA3 rs738409 Polymorphism Associated with Hepatic Steatosis and Advanced Fibrosis in Patients with Chronic Hepatitis C Virus: A Meta-Analysis

Fan JH, Xiang MQ, Li QL, Shi HT, Guo JJ

BACKGROUND/AIMS: The recognition of a correlation between patatin-like phospholipase domain containing-protein 3 (PNPLA3) rs738409 (C>G) and the severity of liver steatosis or fibrosis in chronic hepatitis C (CHC) has not...
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Association of lipoprotein lipase (LPL) single nucleotide polymorphisms with type 2 diabetes mellitus

Cho YS, Go MJ, Han HR, Cha SH, Kim HT, Min H, Shin HD, Park C, Han BG, Cho NH, Shin C, Kimm K, Oh B

The etiology and pathogenesis of type 2 diabetes mellitus (T2DM) are not completely understood although it is often associated with other conditions such as obesity, hypertension, and dyslipidemia. Lipoprotein lipase...
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Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

Akuta N, Kawamura Y, Arase Y, Suzuki F, Sezaki H, Hosaka T, Kobayashi , Kobayashi , Saitoh S, Suzuki Y, Ikeda K, Kumada H

BACKGROUND/AIMS: It is important to determine the noninvasive parameters of histological features in nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the value of genetic...
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