- Development of an oligonucleotide microarray for simultaneous detection of two canine MDR1 genotypes and association between genotypes and chemotherapy side effects
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Lee JJ, Lin HY, Chen CA, Lin CS, Wang LC
- KMID: 2434774
- J Vet Sci.
- 2019 Jan;20(1):27-33.
- doi: 10.4142/jvs.2019.20.1.27
Canine MDR1 gene mutations produce translated P-glycoprotein, an active drug efflux transporter, resulting in dysfunction or over-expression. The 4-base deletion at exon 4 of MDR1 at nucleotide position 230 (nt230[del4])... -
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- Elevated plasma YKL-40 level is found in the dogs with cancer and is related to poor prognosis
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Cheng KC, Lee JJ, Wang SL, Lin CY, Tseng CT, Lin CS, Liao AT
- KMID: 2464099
- J Vet Sci.
- 2019 Sep;20(5):e53.
- doi: 10.4142/jvs.2019.20.e53
YKL-40, a secreted glycoprotein, may serve as an autoantigen, which mediates multiple inflammatory diseases and cancers. A high YKL-40 serum level is correlated with metastasis and poor survival in a... -
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- Prospects of stem cell treatment in benign urological diseases
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Alwaal A, Hussein AA, Lin CS, Lue TF
- KMID: 2155300
- Korean J Urol.
- 2015 Apr;56(4):257-265.
- doi: 10.4111/kju.2015.56.4.257
Stem cells (SCs) are undifferentiated cells that are capable of self-renewal and differentiation and that therefore contribute to the renewal and repair of tissues. Their capacity for division, differentiation, and... -
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- Effective Antiviral Activity of the Tyrosine Kinase Inhibitor Sunitinib Malate against Zika Virus
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Lin CS, Huang SH, Yan BY, Lai HC, Lin CW
- KMID: 2524056
- Infect Chemother.
- 2021 Dec;53(4):730-740.
- doi: 10.3947/ic.2021.0111
Background:(Introduction): Zika virus (ZIKV), a mosquito-borne flavivirus, causes the outbreaks of Latin America in 2015 - 2016, with the incidence of neurological complications. Sunitinib malate, an orally bioavailable malate salt... -
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- Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells
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Wang CY, Lin CS, Hua CH, Jou YJ, Liao CR, Chang YS, Wan L, Huang SH, Hour MJ, Lin CW
- KMID: 2432067
- Biomol Ther.
- 2019 Jan;27(1):54-62.
- doi: 10.4062/biomolther.2017.237
Cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA), a triterpenoid compound, was purified from Elaeagnus oldhamii Maxim. This traditional medicinal plant has been used for treating rheumatoid arthritis and lung disorders as well as... -
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