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Feasibility of Loop-Mediated Isothermal Amplification for Rapid Detection of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Tissue Samples

Kim SG, Choi GW, Choi WS, Lim CS, Jang WS, Bae JH

Background: To date, few studies have investigated the feasibility of the loop-mediated isothermal amplification (LAMP) assay for identifying pathogens in tissue samples. This study aimed to investigate the feasibility of...
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External validation of risk prediction platforms for pancreatic fistula after pancreatoduodenectomy using nomograms and artificial intelligence

Yoon SJ, Kwon W, Lee OJ, Jung JH, Shin YC, Lim CS, Kim H, Jang JY, Shin SH, Heo JS, Han IW

Purpose: Postoperative pancreatic fistula (POPF) is a life-threatening complication following pancreatoduodenectomy (PD). We previously developed nomogram- and artificial intelligence (AI)-based risk prediction platforms for POPF after PD. This study aims to...
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Development and External Validation of Survival Prediction Model for Pancreatic Cancer Using Two Nationwide Databases: Surveillance, Epidemiology and End Results (SEER) and Korea Tumor Registry System-Biliary Pancreas (KOTUS-BP)

Kang JS, Mok L, Heo JS, Han IW, Shin SH, Yoon YS, Han HS, Hwang DW, Lee JH, Lee WJ, Park SJ, Park JS, Kim Y, Lee H, Yu YD, Yang JD, Lee SE, Park IY, Jeong CY, Roh Y, Kim SR, Moon JI, Lee SK, Kim HJ, Lee S, Kim H, Kwon W, Lim CS, Jang JY, Park T

Background/Aims: Several prediction models for evaluating the prognosis of nonmetastatic resected pancreatic ductal adenocarcinoma (PDAC) have been developed, and their performances were reported to be superior to that of the...
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Performance Evaluation of the CareGENETM Zika Virus Reverse Transcription-PCR Kit for Urine Specimen

Kim GW, Park BG, Kwak SY, Jang WS, Nam J, Lim CS

Background: Zika virus (ZIKV) is a major health concern worldwide, highlighting the importance of accurate and reliable viral detection to control transmission. The careGENETM ZIKV Reverse Transcription-Polymerase Chain Reaction (RT-PCR)...
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Causal effect of alcohol use on the risk of end-stage kidney disease and related comorbidities: a Mendelian randomization study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: An inverse observational association between alcohol use and the risk of chronic kidney disease (CKD) or end-stage kidney disease (ESKD) has been reported. The causal effect of alcohol use...
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Performance Evaluation of Biozentech Malaria Scanner in Plasmodium knowlesi and P. falciparum as a New Diagnostic Tool

Firdaus ER, Park JH, Muh F, Lee SK, Han JH, Lim CS, Na SH, Park WS, Park JH, Han ET

The computer vision diagnostic approach currently generates several malaria diagnostic tools. It enhances the accessible and straightforward diagnostics that necessary for clinics and health centers in malaria-endemic areas. A new...
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Clinical Usefulness of LabChip Real-time PCR using Lab-On-a-Chip Technology for Diagnosing Malaria

Kim J, Lim DH, Mihn DC, Nam J, Jang WS, Lim CS

As malaria remains a major health problem worldwide, various diagnostic tests have been developed, including microscopy-based and rapid diagnostic tests. LabChip real-time PCR (LRP) is a small and portable device...
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Formation of Full Thickness Macular Hole Following Pars Plana Vitrectomy and Internal Limiting Membrane Peeling and Its Spontaneous Closure

Lim CS, El-Khayat A, Mokashi A

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Risk factors of elderly patients with postoperative delirium following major abdominal surgery for cancer

Heo SC, Ahn HS, Shin R, Lim CS, Han DS

Purpose: Postoperative delirium (POD) is a common complication in elderly patients after major abdominal surgery for cancer. Although POD is related with a poor outcome, there have not been many...
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Impact of health-related quality of life on survival after dialysis initiation: a prospective cohort study in Korea

Lee J, Kim YC, Kwon K, Li L, Oh S, Kim DH, An JN, Cho JH, Kim DK, Kim YL, Oh YK, Lim CS, Kim YS, Lee JP

Background: The effect of each health-related quality of life (HRQOL) component on hemodialysis prognosis has not been well studied. We aimed to investigate the clinical factors associated with HRQOL and...
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Cumulative fluid balance and mortality in elderly patients with acute kidney injury requiring continuous renal-replacement therapy: a multicenter prospective cohort study

Jhee JH, Park JY, An JN, Kim DK, Joo KW, Oh YK, Lim CS, Kim YS, Han SH, Yoo TH, Kang SW, Lee JP, Park JT

Background: The effect of fluid balance on outcomes in elderly patients with acute kidney injury (AKI) requiring continuous renal-replacement therapy (CRRT) is not explained well. We investigated outcomes according to...
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Operation and Management of Seoul Metropolitan City Community Treatment Center for Mild Condition COVID-19 Patients

Lee SY, Song KJ, Lim CS, Kim BG, Chai YJ, Lee JK, Kim SH, Lim HJ

Background: In response to the disaster of coronavirus disease 2019 (COVID-19) pandemic, Seoul Metropolitan Government (SMG) established a patient facility for mild condition patients other than hospital. This study was...
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Hematopoietic Stem Cell Registry Report: 2018

Kang ES, Lim CS, Han KS, Kim DW

Background: Hematopoietic stem cell (HSC) transplantation is an important therapeutic option for many malignant and non-malignant diseases. The whole transplant process involves multiple areas and complex steps. The laboratory procedures...
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Seroprevalence of Anti-SARS-CoV-2 Antibodies among Outpatients in Southwestern Seoul, Korea

Noh JY, Seo YB, Yoon JG, Seong H, Hyun H, Lee J, Lee N, Jung S, Park MJ, Song W, Yoon J, Lim CS, Ryou J, Lee JY, Kim SS, Cheong HJ, Kim WJ, Yoon SY, Song JY

Serosurveillance studies reveal the actual disease burden and herd immunity level in the population. In Seoul, Korea, a cross-sectional investigation showed 0.07% anti-severe acute respiratory syndrome coronavirus-2 antibody seropositivity among...
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The Implication of Cytogenetic Alterations in Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm Identified by Fluorescence In Situ Hybridization and Their Potential Diagnostic Utility

Lim CS, Im K, Lee DS, Kwon W, Kim JR, Han Y, Kim SW, Jang JY

Background/Aims: We investigated chromosomal aberrations in patients with pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasm (IPMN) by fluorescence in situ hybridization (FISH) to identify cytogenetic changes and molecular...
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Reduced risk for chronic kidney disease after recovery from metabolic syndrome: A nationwide populationbased study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Han K, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: Metabolic syndrome (MetS) is linked to various chronic comorbidities, including chronic kidney disease (CKD). However, few large studies have addressed whether recovery from MetS is associated with reduction in...
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Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva

Yoon JG, Yoon J, Song JY, Yoon SY, Lim CS, Seong H, Noh JY, Cheong HJ, Kim WJ

Background: Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period. Methods: We evaluated the viral dynamics in various body fluid specimens,...
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Evaluation of Diagnostic Performance of Three Real-Time PCR Assays for the Detection of Mycobacteria Species

Kim Sw, Park YH, Ko YJ, Kim YH, Kim CH, Lim CS

Background: The disease burden caused by Mycobacterium tuberculosis (MTB) complex continues to decrease in most countries. However, the diseases caused by the nontuberculous mycobacteria (NTM) become a public health problem....
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Cellulitis Caused by a Novel Cupriavidus Species Strain J1218 Identified by Whole Genome Sequencing

Ko YJ, Yoon SY, Lim CS, Lee CK

We report a case of cellulitis caused by a novel Cupriavidus species identified using whole-genome sequence analysis. Subcutaneous tissue biopsies from the left lower leg of a 67-year-old man who...
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Spatial Learning and Motor Deficits in Vacuolar Protein Sorting-associated Protein 13b (Vps13b) Mutant Mouse

Kim MJ, Lee RU, Oh J, Choi JE, Kim H, Lee K, Hwang SK, Lee JH, Lee JA, Kaang BK, Lim CS, Lee YS

Vacuolar protein sorting-associated protein 13B (VPS13B), also known as COH1, is one of the VPS13 family members which is involved in transmembrane transport, Golgi integrity, and neuritogenesis. Mutations in the...
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