- Anti-metastatic Effect of Natural Product-motivated Synthetic PPAR-γ Ligands
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Li Dd, Wang Y, Ju Z, Kim EL, Hong J, Jung JH
- KMID: 2530936
- Nat Prod Sci.
- 2022 Jun;28(2):80-88.
- doi: 10.20307/nps.2022.28.2.80
Colorectal cancer is one of the most common cancers globally, ranking second for the number of cancer-related deaths. Metastasis has been reported as the main cause of death in patients... -
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- Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay
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Xiao B, Li Dd, Wang Y, Kim EL, Zhao N, Jin SW, Bai DH, Sun LD, Jung JH
- KMID: 2519617
- Biomol Ther.
- 2021 Sep;29(5):519-526.
- doi: 10.4062/biomolther.2021.008
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib... -
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