- Differential Methylation Pattern of ID4, SFRP1, and SHP1 between Acute Myeloid Leukemia and Chronic Myeloid Leukemia
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Uhm KO, Lee ES, Lee YM, Park JS, Kim SJ, Kim BS, Kim HS, Park SH
- KMID: 1779169
- J Korean Med Sci.
- 2009 Jun;24(3):493-497.
- doi: 10.3346/jkms.2009.24.3.493
To gain insight into the differential mechanism of gene promoter hypermethylation in acute and chronic leukemia, we identified the methylation status on one part of 5'CpG rich region of 8... -
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- Analysis of Acute Myeloid Leukemia in Korean Patients with Sole Trisomy 6
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Yu S, Kwon MJ, Lee ST, Woo HY, Park H, Kim SH
- KMID: 1791959
- Ann Lab Med.
- 2014 Sep;34(5):402-404.
- doi: 10.3343/alm.2014.34.5.402
No abstract available. -
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- A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
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Lee JH, Park C, Kim SH, Shin MG
- KMID: 2373559
- Ann Lab Med.
- 2016 Jul;36(4):371-374.
- doi: 10.3343/alm.2016.36.4.371
No abstract available. -
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- Near-tetraploidy Acute Myeloid Leukemia with RUNX1-RUNX1T1 Rearrangement Due to Cryptic t(8;21)
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Im M, Lee JK, Lee DY, Hong YJ, Hong SI, Kang HJ, Chang YH
- KMID: 1781603
- Korean J Lab Med.
- 2009 Dec;29(6):510-514.
- doi: 10.3343/kjlm.2009.29.6.510
Tetraploidy or near-tetraploidy is a rare cytogenetic abnormality found in AML, and is divided into primary and secondary forms. The secondary tetraploidy or near-tetraploidy found in AML is known to... -
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- Novel Mutations in CEBPA in Korean Patients with Acute Myeloid Leukemia with a Normal Karyotype
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Kim S, Kim DH, Jang JH, Jung CW, Jang MA, Ki CS, Kim JW, Kim SH, Kim HJ
- KMID: 1245256
- Ann Lab Med.
- 2012 Mar;32(2):153-157.
- doi: 10.3343/alm.2012.32.2.153
Mutations in the transcription factor CCAAT/enhancer binding protein alpha gene (CEBPA) are found in 5-14% of the patients with AML and have been associated with a favorable clinical outcome. In... -
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- Alteration of the SETBP1 Gene and Splicing Pathway Genes SF3B1, U2AF1, and SRSF2 in Childhood Acute Myeloid Leukemia
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Choi HW, Kim HR, Baek HJ, Kook H, Cho D, Shin JH, Suh SP, Ryang DW, Shin MG
- KMID: 2363158
- Ann Lab Med.
- 2015 Jan;35(1):118-122.
- doi: 10.3343/alm.2015.35.1.118
BACKGROUND: Recurrent somatic SET-binding protein 1 (SETBP1) and splicing pathway gene mutations have recently been found in atypical chronic myeloid leukemia and other hematologic malignancies. These mutations have been comprehensively... -
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- Prevalence of FLT3 Internal Tandem Duplication in Adult Acute Myelogenous Leukemia
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Lee JN, Kim HR, Shin JH, Joo YD
- KMID: 1781490
- Korean J Lab Med.
- 2007 Aug;27(4):237-243.
- doi: 10.3343/kjlm.2007.27.4.237
BACKGROUND: fms-like tyrosine kinase (FLT3), a member of the class III receptor tyrosine kinases, regulates the proliferation and differentiation of hematopoietic stem cells. An internal tandem duplication of the... -
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- Identification of Two Novel NPM1 Mutations in Patients with Acute Myeloid Leukemia
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Jeon Y, Seo SW, Park S, Park S, Kim SY, Ra EK, Park SS, Seong MW
- KMID: 1781299
- Ann Lab Med.
- 2013 Jan;33(1):60-64.
- doi: 10.3343/alm.2013.33.1.60
BACKGROUND: Genetic abnormalities in adult AML are caused most frequently by somatic mutations in exon 12 of the NPM1 gene, which is observed in approximately 35% of AML patients and... -
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- Low Frequency and Variability of FLT3 Mutations in Korean Patients with Acute Myeloid Leukemia
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Bang SM, Ahn JY, Park J, Park SH, Park J, Cho EK, Shin DB, Lee JH, Yoo SJ, Jeon IS, Kim YK, Kim HJ, Kim HN, Lee IK, Kang HJ, Shin HY, Ahn HS
- KMID: 1783069
- J Korean Med Sci.
- 2008 Oct;23(5):833-837.
- doi: 10.3346/jkms.2008.23.5.833
FLT3 mutations are common genetic changes, and are reported to have prognostic significance in acute myeloid leukemia (AML). The FLT3 internal tandem duplication (ITD) and the D835 activating mutation in... -
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- Clinical Prognostic Factors in 86 Chinese Patients with Primary Myelodysplastic Syndromes and Trisomy 8: A Single Institution Experience
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Yue QF, Chen L, She XM, Hu B, Hu Y, Zou P, Liu XY
- KMID: 2374040
- Yonsei Med J.
- 2016 Mar;57(2):358-364.
- doi: 10.3349/ymj.2016.57.2.358
PURPOSE: The objective was to determine the characteristics and prognostic factors of 86 Chinese patients with trisomy 8 aberrations and compare the prognostic value of International Prognostic System (IPSS) and... -
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