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Characteristic profiles of biofilm, enterotoxins and virulence of Staphylococcus aureus isolates from dairy cows in Xinjiang Province, China

Wu Y, Li J, Qiao M, Meng D, Meng Q, Qiao J, Zhang X, Wang L, Cai K, Zhang J, Zhang Z, Yu W, Cai X

As an important zoonotic pathogen, Staphylococcus aureus has led to serious mastitis and endometritis in infected dairy cows. In this study, a total of 164 strains of S. aureus were...
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Acute toxicity of benzalkonium chloride in Balb/c mice following intratracheal instillation and oral administration

Lee H, Park K

Benzalkonium chloride is a cationic surfactant widely used as a disinfectant, preservative, and sanitizer in many public places as well as domestically. The purpose of this study is to compare...
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Foeniculum vulgare as Valuable Plant in Management of Women's Health

Mahboubi M

This review paper evaluates use of Foeniculum vulgare extracts as a popular female plant in management of different ailments of women. Information in this paper was gathered from accessible sources...
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach

Sood D, Kumar N, Singh A, Sakharkar , Tomar V, Chandra R

Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary...
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A serine/threonine phosphatase 1 of Streptococcus suis type 2 is an important virulence factor

Fang L, Zhou J, Fan P, Yang Y, Shen H, Fang W

Streptococcus suis is regarded as one of the major pathogens of pigs, and Streptococcus suis type 2 (SS2) is considered a zoonotic bacterium based on its ability to cause meningitis...
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Biological activities and acute oral toxicity of citronella and lemongrass oil

Park JY, Kim JY, Jang SH, Kim HJ, Lee SJ, Park SC

This study was performed to investigate the antibacterial, antioxidant, and termite repellent effects of citronella oil (CiO) and lemongrass oil (LO). When the antibacterial activity against Staphylococcus (S.) aureus with...
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Changes of characterization of Salmonella Typhimurium isolate following sequential exposures to porcine neutrophil

Lee HS, Kim A, Youn M, Lee JY, Lim SK, Kang HY, Yoo HS, Park JW, Wee SH, Jung SC

  • KMID: 1991790
  • Korean J Vet Res.
  • 2013 Mar;53(1):29-35.
To develop a live vaccine candidate using an attenuated strain of Salmonella Typhimurium (ST), biochemical properties, plasmid profile, PFGE patterns and pathogenic analysis of the ST isolate were carried out...
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Mouse Single Oral Dose Toxicity Test of Bupleuri Radix Aqueous Extracts

Kim KH, Gam CO, Choi SH, Ku SK

  • KMID: 2052546
  • Toxicol Res.
  • 2012 Mar;28(1):11-18.
The aim of this study was to evaluate the single oral dose toxicity of Bupleuri Radix (BR) aqueous extracts, it has been traditionally used as anti-inflammatory agent, in male and...
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Acute Toxicity and General Pharmacological Action of QGC EXT

Lee JM, Im WJ, Nam YJ, Oh KH, Lim JC, Whang WK, Sohn UD

It has been shown that QGC isolated and purified from Rumecis folium found protective effects of gastritis and esophagitis which EXT is an ethanol extract of it. We examined acute...
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Toxicity of Methylcyclohexane and Its Effect on the Reproductive System in SD Rats

Kim HY, Kang MG, Kim TG, Kang CW

  • KMID: 2317026
  • Saf Health Work.
  • 2011 Sep;2(3):290-300.
OBJECTIVES: There is limited data regarding the toxicity of methylcyclohexane, despite its wide use in rubber adhesives, paint diluents, and cleansing agents. This study aimed to verify the toxicity and...
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Acute Oral or Dermal and Repeated Dose 90-Day Oral Toxicity of Tetrasodium Pyrophosphate in Spraque Dawley (SD) Rats

Seo DS, Kwon M, Sung HJ, Park CB

  • KMID: 2380164
  • Environ Health Toxicol.
  • 2011 ;26(1):e2011014.
OBJECTIVES: Tetrasodium pyrophosphate (TSP) is used in processed meat products, as an emulsifier in cheese, and as a color preservative in soybean paste. However, little is known about its toxicity....
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Biological Activity and Single Oral Dose Toxicity of Dansam-samultang

Lee IC, Kim BH, Kim MK

In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Dansam-samultang to evaluate its use as a functional ingredient...
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Investigations of Samwhang-sasimtang Extracts on Biological Activities In Vitro and Vivo

Lee IC, Kim BH, Kim MK

In this study, we investigated the in vitro antioxidative effects, antimicrobial activities and single oral dose toxicity of the extracts from Samwhang-sasimtang to evaluate its use as a functional ingredient...
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Detection of Botulinum Neurotoxin Type A by In Vitro Bioassay Based on Endopeptidase Activity

Kim YJ, Baek JH, Kim JH, Kim BS, Rhie GE, Yoo CK, Shin NR

Botulinum neurotoxin type A (BoNT/A) is a metalloprotease that cleaves SNAP-25 (synaptosome-associated protein of 25 kDa), a specific cellular protein essential for neurotransmitter release. As well as mouse bioassay to...
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Comparative acute toxicity of quaternary ammonium lidocaine derivative QX-314 to lidocaine in mice

Lee SM, Chung KD, Son YS, Yu SJ, Ryu KH, Lee SH, Cho HS

  • KMID: 2263347
  • Anesth Pain Med.
  • 2009 Jan;4(1):5-10.
BACKGROUND: The current study examined the acute systemic toxicity of QX-314 that there have been few research results for this so far. In order to be useful as a drug,...
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In vivo alternative testing with zebrafish in ecotoxicology

Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Lee HK, Lee BH, Park JH

Although rodents have previously been used in ecotoxicological studies, they are expensive, time-consuming, and are limited by strict legal restrictions. The present study used a zebrafish (Danio rerio) model and...
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Metoclopramide protection of diazinon-induced toxicosis in chickens

Al-Zubaidy MH, Mohammad F

The efficacy of metoclopramide for preventing organo-phosphate insecticide-induced (diazinon) toxicosis wasevaluated in 7~14 days old chicks. Injection of metoclo-pramide at 25mg/kg, s.c. 15min before diazinon increasedthe oral 24 h median...
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Anthelmintic efficacy of extracts of Spigelia anthelmia Linn on experimental Nippostrongylus braziliensis in rats

Jegede OC, Ajanusi JO, Adaudi AO, Agbede RI

Spigelia anthelmia Linn is used as a herb and is a common annual weed of cultivation in open re-growths, on unused land in towns as well as on road sides....
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Helicobacter pylori Urease Induces Mouse Death

Baik SC, Kang HL, Seo JH, Park ES, Rhee KH, Cho MJ

  • KMID: 1574158
  • J Bacteriol Virol.
  • 2005 Sep;35(3):175-181.
The component of Helicobacter pylori responsible for mouse death was identified and partially characterized. Mice that were injected with H. pylori cell lysate showed pathological changes such as decreased activity,...
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PC12 Cell Apoptosis Mediated by Reactive Oxygen Species with Various Agents is Reduced Effectively by Flavonoid Antioxidants

Joe S, Bae JA, Lee KY

  • KMID: 1883448
  • Chonnam Med J.
  • 2004 Dec;40(4):173-179.
Reactive oxygen species (ROS) has many biological roles. Apoptosis is also induced by ROS. In this study, we show the involvement of ROS on the PC12 cell apoptosis induced by...
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