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Phascolarctobacterium-producing propionate and acute rejection of kidney transplant recipients

Cho H, Park JI, Kim JE, Lee 4 JW, Kim YC, Lee JP, Kim DK, Kim YS, Lee H

Background: Acute rejection (AR) is associated with worse long-term allograft survival. Therefore, identifying and regulating the potential risk factors of AR is very important. Growing evidence has shown that gut...
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Clinical significance of delayed or slow graft function in kidney transplantation recipients

Song J, Jeong S, Min S, Ha J, Kim YS, Lee JP, Jeong JC, Lee H

Background: With increasing total number of patients who receive expanded criteria donor kidneys, it is important to maintain the function of kidney grafts. Methods: Retrospective medical records of kidney transplantation (KT)...
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The cumulative dose-dependent benefit of metformin in kidney transplantation recipients

Kwon S, Kim YC, Kwon H, Jung IM, Yoo KD, Lee JS, Kim YS, Kim YH, Lee JP

Background: The status of metformin as a primary treatment of choice is concrete, moreover it has recently been recommended for advanced chronic kidney disease patients. Although, the evidence of metformin...
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Sodium-glucose cotransporter 2 inhibitors in kidney transplant recipients

Lim JH, Kwon S, Jung HY, Choi JY, Park SH, Kim CD, Kim YL, Lee JP, Cho JH

Background: The effect and safety of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have not been investigated in kidney transplant recipients (KTRs) with diabetes. We evaluated the impact of SGLT2i in a...
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Effects of residential greenness on clinical outcomes of patients with chronic kidney disease: a large-scale observation study

Park JY, Jung J, Kim YC, Lee H, Kim E, Kim YS, Kim H, Lee JP

Background: As industrialization and urbanization are accelerating, the distribution of green areas is decreasing, particularly in developing countries. Since the 2000s, the effects of surrounding greenness on self-perceived health, including...
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Causal effect of alcohol use on the risk of end-stage kidney disease and related comorbidities: a Mendelian randomization study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Kim K, Kim YC, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: An inverse observational association between alcohol use and the risk of chronic kidney disease (CKD) or end-stage kidney disease (ESKD) has been reported. The causal effect of alcohol use...
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Impact of health-related quality of life on survival after dialysis initiation: a prospective cohort study in Korea

Lee J, Kim YC, Kwon K, Li L, Oh S, Kim DH, An JN, Cho JH, Kim DK, Kim YL, Oh YK, Lim CS, Kim YS, Lee JP

Background: The effect of each health-related quality of life (HRQOL) component on hemodialysis prognosis has not been well studied. We aimed to investigate the clinical factors associated with HRQOL and...
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Cumulative fluid balance and mortality in elderly patients with acute kidney injury requiring continuous renal-replacement therapy: a multicenter prospective cohort study

Jhee JH, Park JY, An JN, Kim DK, Joo KW, Oh YK, Lim CS, Kim YS, Han SH, Yoo TH, Kang SW, Lee JP, Park JT

Background: The effect of fluid balance on outcomes in elderly patients with acute kidney injury (AKI) requiring continuous renal-replacement therapy (CRRT) is not explained well. We investigated outcomes according to...
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Comorbidities can predict the mortality of acute kidney injury requiring continuous renal replacement therapy: comparison with the Charlson comorbidity index

Lee J, Jung J, Lee J, Park JT, Kim YC, Kim DK, Lee JP, Shin SJ, Park JY

Background: Comorbid conditions are important in the survival of patients with severe acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). The weights assigned to comorbidities to predict survival...
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Analysis of time trends in preemptive kidney transplantation and effect of pre-transplant dialysis duration on graft survival: a nationwide cohort study

Lim JH, Lee SH, Lee YH, Lee JP, Yang J, Kim MS, Park SH, Kim CD, Cho JH

Background: Preemptive kidney transplantation (KT) has advantages on graft survival, quality of life, and medical expense. However, the trend of preemptive KT over time is not known. This study analyzed...
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Gut Faecalibacterium may improve impaired tacrolimus metabolism in kidney transplant recipients with cytochrome polymorphism

Kim JE, Kim HE, Cho H, Park JI, Lee JW, Yang SH, Lee JP, Ha J, Kim YS, Lee H

Background: The gut microbiota alters expression of drug-metabolizing enzymes and transporters, and consequently affects therapeutic dose and response of medicines. We aimed to investigate the effect of the gut microbiome...
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Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea

Kim K, Lee SH, Lee SW, Lee JP, Chin HJ

Background/Aims: This study aimed to investigate long-term temporal trends and outcomes of biopsy-proven kidney diseases in a multicenter kidney biopsy cohort, focusing on hypertension and diabetes, the leading causes...
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Comparison of dietary intake patterns in hemodialysis patients by nutritional status: A cross-sectional analysis

Lee JE, Kim HJ, Lee MJ, Kwon YE, Kyung MS, Park JT, Lee JP, Kim SH, Kim JH, Oh HJ, Ryu DR

Background: Although appropriate dietary adjustments in hemodialysis (HD) patients are important, most HD patients have difficulty adhering to dietary therapy due to the stress of a restricted-food diet or loss...
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Reduced risk for chronic kidney disease after recovery from metabolic syndrome: A nationwide populationbased study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Han K, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: Metabolic syndrome (MetS) is linked to various chronic comorbidities, including chronic kidney disease (CKD). However, few large studies have addressed whether recovery from MetS is associated with reduction in...
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Association of Blood Pressure at Specific Time-Points with 1-Year Renal Outcomes in Patients with Diabetic Chronic Kidney Disease

Ryu JW, Cha RH, Lee H, Kim YS, Lee JP, Song YR, Kim SG, Kim SJ

BACKGROUND: The 24-hour mean blood pressure (mBP) is the best predictor of organ damage; however, it is not easily applicable in clinical practice. The APrODiTe study suggested that systolic blood...
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Risk of cancer in pre-dialysis chronic kidney disease: A nationwide population-based study with a matched control group

Park S, Lee S, Kim Y, Lee Y, Kang MW, Han K, Han SS, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

BACKGROUND: Cancer risk and epidemiology in pre-dialysis chronic kidney disease (CKD) warrant further investigation in a large-scale cohort. METHODS: We performed a nationwide population-based study using the national health insurance database...
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Maternal and fetal outcomes of pregnancies in kidney donors: A 30-year comparative analysis of matched non-donors in a single center

Yoo KD, Lee H, Kim Y, Park S, Park JS, Hong JS, Jeong CW, Kim HH, Lee JP, Kim DK, Oh KH, Joo KW, Kim YS

BACKGROUND: Woman kidney donors face obstetric complication risks after kidney donation, such as gestational hypertension and preeclampsia. Studies on childbirth-related complications among Asian women donors are scarce. METHODS: This retrospective cohort...
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Effectiveness of group cognitive behavioral therapy with mindfulness in end-stage renal disease hemodialysis patients

Sohn BK, Oh YK, Choi JS, Song J, Lim A, Lee JP, An JN, Choi HJ, Hwang JY, Jung HY, Lee JY, Lim CS

BACKGROUND: Many patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) experience depression. Depression influences patient quality of life (QOL), dialysis compliance, and medical comorbidity. We developed and applied a...
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The Effect of Mycophenolate Mofetil versus Cyclosporine as Combination Therapy with Low Dose Corticosteroids in High-risk Patients with Idiopathic Membranous Nephropathy: a Multicenter Randomized Trial

Choi JY, Kim DK, Kim YW, Yoo TH, Lee JP, Chung HC, Cho KH, An WS, Lee DH, Jung HY, Cho JH, Kim CD, Kim YL, Park SH

BACKGROUND: Appropriate immunosuppressive therapy for patients with idiopathic membranous nephropathy (MN) remains controversial. The effect of mycophenolate mofetil (MMF) versus cyclosporine (CsA) combined with low-dose corticosteroids was evaluated in patients...
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Physician perceptions of blood pressure control in patients with chronic kidney disease and target blood pressure achievement rate

Cha RH, Lee H, Lee JP, Song YR, Kim SG, Kim YS

BACKGROUND: Blood pressure (BP) control is the most-established method for the prevention of chronic kidney disease (CKD) progression. However, the ideal BP target for CKD patients is still under debate. METHODS:...
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