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Fibroblast Growth Factor 21 Mimetics for Treating Atherosclerosis

Kwok KH, Lam KS

Fibroblast growth factor 21 (FGF21) is an atypical member of the FGF family. Acting in an endocrine fashion, it increases glucose uptake, modulates lipid metabolism, and sensitizes insulin response in...
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Heterogeneity of white adipose tissue: molecular basis and clinical implications

Kwok KH, Lam KS, Xu A

Adipose tissue is a highly heterogeneous endocrine organ. The heterogeneity among different anatomical depots stems from their intrinsic differences in cellular and physiological properties, including developmental origin, adipogenic and proliferative...
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Development of a Non-Invasive Liver Fibrosis Score Based on Transient Elastography for Risk Stratification in Patients with Type 2 Diabetes

Lee CH, Seto WK, Ieong K, Lui DT, Fong CH, Wan HY, Chow WS, Woo YC, Yuen MF, Lam KS

Background: In non-alcoholic fatty liver disease (NAFLD), transient elastography (TE) is an accurate non-invasive method to identify patients at risk of advanced fibrosis (AF). We developed a diabetes-specific, non-invasive liver...
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