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The impact of probiotics and vitamin C on the prevention of upper respiratory tract symptoms in two preschool children cohorts

Paduchová Z, Nagyová Z, Wang D, Muchová J

BACKGROUND/OBJECTIVES: The efficacy of Lab4 probiotic and vitamin C combination on the prevention of upper respiratory tract infections (URTIs) was investigated in two studies with children. Our objective was to...
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Role of Probiotics in the Treatment and Prevention of Common Gastrointestinal Conditions in Children

Hojsak I, Kolaček S

Probiotics are live microorganisms that confer health benefits to the host when administered in adequate amounts. Although recommendations for probiotic use should be strain-specific, many systematic reviews, including recommendations from...
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Extracellular Vesicles Released by Lactobacillus paracasei Mitigate Stress-induced Transcriptional Changes and Depression-like Behavior in Mice

Kwon H, Lee EH, Choi J, Park JY, Kim YK, Han PL

  • KMID: 2547934
  • Exp Neurobiol.
  • 2023 Oct;32(5):328-342.
  • doi: 10.5607/en23024
Various probiotic strains have been reported to affect emotional behavior. However, the underlying mechanisms by which specific probiotic strains change brain function are not clearly understood. Here, we report that...
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Lactobacillus reuteri ATG-F4 Alleviates Chronic Stress-induced Anhedonia by Modulating the Prefrontal Serotonergic System

Lee J, Kim EJ, Park GS, Kim J, Kim TE, Lee YJ, Park J, Kang J, Koo JW, Choi TY

  • KMID: 2547933
  • Exp Neurobiol.
  • 2023 Oct;32(5):313-327.
  • doi: 10.5607/en23028
Mental health is influenced by the gut-brain axis; for example, gut dysbiosis has been observed in patients with major depressive disorder (MDD). Gut microbial changes by fecal microbiota transplantation or probiotics...
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Effects of Lactobacillus casei and Aggregatibactor actinomycetemcomitans against Streptococcus mutans according to the Concentration of Sucrose

Jeong SJ

Background: Some studies confirm the reduction of the number of Streptococcus mutans in saliva and dental plaque by Lactobacillus, however, these effects are not always confirmed in in vitro and...
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Total Transit Time and Probiotic Persistence in Healthy Adults: A Pilot Study

Tremblay A, Auger J, Alyousif Z, Caballero Calero SE, Mathieu O, Rivero-Mendoza D, Elmaoui A, Dahl W, Tompkins TA

  • KMID: 2541574
  • J Neurogastroenterol Motil.
  • 2023 Apr;29(2):218-228.
  • doi: 10.5056/jnm22031
Background/Aims Motility, stool characteristics, and microbiota composition are expected to modulate probiotics’ passage through the gut but their effects on persistence after intake cessation remain uncharacterized. This pilot, open-label study aims...
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Efficacy of a Synbiotic Containing Lactobacillus paracasei DKGF1 and Opuntia humifusa in Elderly Patients with Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

Oh JH, Jang YS, Kang D, Kim HS, Kim EJ, Park SY, Kim CH, Min YW, Chang DK

Background/Aims: There is increasing evidence that supplementation with pre- and probiotics appears to have positive effects on irritable bowel syndrome (IBS). The aim of this study was to determine the...
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Comparative antimicrobial activity of human and monkey origin lactic acid bacteria on simian enteric bacteria

Kang PY, Do KH, Koo BS, Lee WK

Lactic acid bacteria as probiotics are intensively used in human and animal species. These probiotic properties of LABs were variable according to bacterial strain and species. However, there was limited...
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Lactobacilli and Cytokine Modifications during Menopause and Their Relation to Vulvar and Vulvovaginal Disorders

Gandhi K, Manales NJ, Garza J, David S, Sanchez A, Ventolini G

Objectives: Female sexual and reproductive health is heavily influenced by the levels and ratios of Lactobacilli species and vaginal cytokines. Menopause marks a profound body change as it shifts to...
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Balanoposthitis with Fungal and Bacterial Coinfection

Son JH, Kim YH, Lee JH

PATIENT CONSENT STATEMENT The patient provided written informed consent for the publication and the use of his images.
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Vaginal health in women and the possibility of predicting preterm birth through microbiome analysis

Hur YM, Kang MN, Kim YJ

Background: With the recent development of next-generation sequencing technology, the microbiome in the body is being revealed in detail. It is also possible to describe the normal vaginal microenvironment and,...
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Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra

Lee HA, Kim JY, Kim J, Nam B, Kim O

The effect of standard therapeutic strategies on Helicobacter pylori infection is diminished over time owing to the emergence of drug resistant strains. In this study, we would like to confirm...
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Combined Effects of Lactobacillus rhamnosus and Egg Oral Immunotherapy in a Mouse Model of Egg Allergy

Kim BG, Kim JN, Jang AS, Shin M

Purpose: Recent clinical trials have successfully used oral immunotherapy (OIT) to treat food allergies. Probiotics have immunomodulatory effects by balancing Th1/Th2 immunity and enhancing regulatory T-cell activity. In this study,...
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Effect of Lactobacillus sakei, a Probiotic Derived from Kimchi, on Body Fat in Koreans with Obesity: A Randomized Controlled Study

Lim S, Moon JH, Shin CM, Jeong D, Kim B

Background: The increased prevalence of obesity has led to increases in the prevalence of chronic diseases worldwide. There is interest whether probiotics have an effect on obesity, but the effectiveness...
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Lactobacillus rhamnosus GG Usage in the Prevention of Gastrointestinal and Respiratory Tract Infections in Children with Gastroesophageal Reflux Disease Treated with Proton Pump Inhibitors: A Randomized Double-Blinded Placebo-Controlled Trial

Dziechciarz P, Krenke K, Szajewska H, Horvath A

Purpose: Proton-pump inhibitors (PPIs) are frequently used to treat gastroesophageal reflux disease (GERD) in children, but recent evidence suggests a potential association between PPI treatment and some types of infections....
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Effects of Lactobacillus pentosus in Children with Allergen-Sensitized Atopic Dermatitis

Ahn SH, Yoon W, Lee SY, Shin HS, Lim MY, Nam YD, Yoo Y

Background: Recent studies have shown that oral administration of probiotics may improve the immune imbalance caused by dysbiosis of the gut microbiome in atopic dermatitis (AD). This study aimed to...
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Effects of antibiotics at sub-minimal inhibitory concentrations on the morphology of Streptococcus mutans and Lactobacillus acidophilus

Kwon YW, Lee SY

Sub-minimal inhibitory concentrations (sub-MICs) of antibiotics may have significant impact on the morphology and biochemical characteristics of target bacteria. This study aimed to examine the morphological changes to sub-MICs of...
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Risk and Protective Factors for Gastrointestinal Symptoms associated with Antibiotic Treatment in Children: A Population Study

Baù M, Moretti A, Bertoni E, Vazzoler V, Luini C, Agosti M, Salvatore

PURPOSE: Gastrointestinal symptoms are often related to antibiotic treatment. Their incidence, risk and protective conditions in children are not well defined and represent the aims of this study. METHODS: We prospectively...
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High-quality draft genome and characterization of commercially potent probiotic Lactobacillus strains

Sulthana A, Lakshmi SG, Madempudi

Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level,...
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Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells

Kim JE, Sharma A, Sharma G, Lee SY, Shin HS, Rudra D, Im SH

Several gut commensals have been shown to modulate host immune response. Recently, many food derived microbes have also been reported to affect the immune system. However, a mechanism to identify...
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