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Accuracy of Creatinine Assay According to Expanded Proficiency Testing in Participants

Jeong TD

Background: In 2020, the accuracy-based creatinine assay (ABCr) proficiency testing (PT) survey was transitioned from an optional to a mandatory program of the Korean Association of External Quality Assessment Service...
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Report on the External Quality Assessment Scheme for Molecular Microbiology, Hepatitis Virus 1, 2 (2016–2021)

Moon HW, Lee TH, Seo JD

The clinical demand for molecular tests is increasing and thus, the need for quality control is also increasing. The Korean Association of External Quality Assessment Service has operated a test...
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Annual Report on the External Quality Assessment Scheme for Clinical Parasitology in Korea (2020–2021)

Jeon J, Won EJ, Byeon KH, Lee YJ, Kim oJ, Shin MG, Shin JH

Annual proficiency surveys were conducted three times a year (2020–2021) by the Korean Association of External Quality Assessment Services. In addition to the image samples (MPI-20-01–MPI-20-04 and MPI-21-01–MPI-21-05), the pre-made...
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Variant Call Format Normalization Contributes to the Accuracy of Variant Nomenclature

You E, Park JH, Park CH, Park KJ

Background: The variant call format (VCF) is currently used to store information on genetic variants. Variant description from the VCF is not unique or standardized. A recent survey indicated that...
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Feasibility of Establishing a Common Cut-Off of Human Leukocyte Antigen Flow Cytometry Crossmatch Using Harmonized Protocols in a Multicenter Setting

Bang HI, Park Y, Song EY, Oh EJ, Lee JH, Kang ES

Background: The results of human leukocyte antigen flow cytometry crossmatch (FCXM) are widely used when making transplant decisions. However, standardization/harmonization is required because the results vary between laboratories. A harmonized...
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Performance Evaluation of BRCA1/2 Genetic Test Using Next-Generation Sequencing Based on Target Capture Method

Kim A, Kim JH, Seo SH, Lee S, Lee W, Chun S

Background: BRCA1 and BRCA2 pathogenic variants are important genetic factors associated with cancers and biomarkers of breast and ovarian cancer. Although Sanger sequencing is regarded as the gold standard...
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Implementation and Validation of an Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantifying Levetiracetam and Lamotrigine in Serum Specimens

Yi A, Lee JH, Nam HG, Han J, Cho SE, Lee SG, Lee EH

We validated an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for quantifying levetiracetam (LEV) and lamotrigine (LAM) in serum specimens. We developed an UHPLCMS/MS method using Triple Quad 4500MD...
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