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Comparison of immunophenotypes between Rag2 knockout mice derived from two different sources

Roh Y, Gong J, Kim J, Jin Y, Song H, Seol A, Park J, Lim Y, Hwang D

Background Recombination activating gene2 (Rag2) knockout (KO) mice are used widely in various research fields, including vaccine development, transplantation studies, and hematopoiesis research, but few studies have compared their phenotypes. This...
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Induction of liver transplant immune tolerance in an outbred rat strain model using tacrolimus

Park M, Na H, Joo Y, Cho K, Kim S, Choi J, Baek J, Choi J, You Y, Cho M

Background Orthotopic liver transplantation is the only option for patients with end-stage liver disease and hepatocellular carcinoma. Post-transplant immunosuppressive therapy is important to prevent graft failure. We investigated the effectiveness of...
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Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide‑induced constipation of SD rats

Kim J, Song H, Choi Y, Jin Y, Roh Y, Seol A, Park S, Park J, Kang H, Hwang D

Background: Disruptions of the intestinal epithelial barrier (IEB) are frequently observed in various digestive diseases, including irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). This study assessed the improvement...
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Epigallocatechin gallate restores the reduction of protein phosphatase 2 A subunit B caused by middle cerebral artery occlusion

Shah M, Kang J, Park D, Koh P

Background Epigallocatechin gallate (EGCG) is a flavonoid compound commonly found in green tea. It exhibits antioxidant, anti-inflammatory, and neuroprotective effects in cerebral ischemia. Protein phosphatase 2 A (PP2A) is an important...
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Effects of Cudrania tricuspidata and Sargassum fusiforme extracts on hair growth in C57BL/6 mice

Rajan P, Natraj P, Kim N, Kim J, Choi H, Han C

Background Cudrania tricuspidata is a perennial plant, and Sargassum fusiforme is a brown seaweed with numerous potential benefits, including anticancer, anti-inflammatory, and antioxidant activities. However, the efficacies of C. tricuspidata and...
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