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Comparison of murine retroorbital plexus and facial vein blood collection to mitigate animal ethics issues

Jo EJ, Bae E, Yoon JH, Kim JY, Han JS

Background: Blood collection is an important procedure used in animal experiments. Blood collection methods that reduce pain, injury, and stress in experimental animals are important with regard to animal ethics....
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A comparative study on intraocular pressure under various anesthetics in cynomolgus monkeys (Macaca fascicularis)

Lee HS, Kim DH, Kim SH, Kang MS, Suh HN

Background: Nonhuman primates (NHPs) are superior model for ocular research due to its morphological and physiological similarities with humans. Thus, the effect of four different anesthetic combinations [ketamine (10 mg/...
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A guide to reducing adverse outcomes in rabbit models of sciatic nerve injury

Orozco E, Masuda K, Shah SB

Background: Peripheral nerve damage can have debilitating consequences. Rabbit sciatic nerve transection models allow the effective evaluation of surgical repair strategies for large nerve gaps. Despite advantages in size, ease...
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Intratracheal inoculation of human varicella zoster virus (VZV; MAV strain) vaccine successfully induced VZV IgG antibodies in rhesus monkeys

Kim JM, Park CG

Background: The objective of this study was to investigate whether the use of live attenuated varicella zoster virus (VZV) MAV vaccination can efficiently induce VZV antibody production in naive rhesus...
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