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Correlation between Serum Lipid Parameters and Interleukin-10 Concentration in Obese Individuals

Kim SJ, Lim J, Nam GE, Park HS

Background: The role of interleukin-10 (IL-10) in humans is controversial because IL-10 has been proposed to exhibit both pro- and anti-inflammatory effects. We aimed to determine the relationships between the...
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Goal Attainment Rate for Parameters of Metabolic Adjustment in Elderly Patients with Type 2 Diabetes Taking a Hypoglycemic Agent

Shim KH, Hwang MS, Park JE, Jung JH, Lee JH, Song BR

BACKGROUND: This study aimed to investigate the goal attainment rates for hemoglobin A1c (HbA1c), blood pressure (BP), and low-density lipoprotein cholesterol (LDL-C) in elderly patients with type 2 diabetes. METHODS: The...
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Effects of folic acid supplementation on serum homocysteine levels, lipid profiles, and vascular parameters in post-menopausal Korean women with type 2 diabetes mellitus

Vijayakumar A, Kim EK, Kim H, Choi YJ, Huh KB, Chang N

BACKGROUND/OBJECTIVES: Complications of diabetes, such as cardiovascular disease, are associated with increased mortality among type 2 diabetes mellitus patients. Homocysteine has been recently identified as a predictor of cardiovascular disease-related...
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Prevalence, Treatment Pattern and Resource Use in Patients with Mixed Dyslipidemia Using Lipid Modifying Agents in Korea (PRIMULA): An Observational Study

Park CS, Kim HS, Lee SH, Han KH, Kim SH, Kim DI, Lee MK, Sung JD, Ahn YK, Park JH, Baek SH

OBJECTIVE: Limited information is available on the effectiveness of lipid-modifying therapy (LMT) for low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) in the Korean population. The objective...
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Effects of Small Dense LDL in Diabetic Nephropathy in Females with Type 2 Diabetes Mellitus

Ryu S, Kim Y, Kim MK, Kwon HS, Baek KH, Song KH, Yun KJ

OBJECTIVE: This study investigated the association between small-dense low-density lipoprotein (sdLDL) and diabetic nephropathy (DN) in type 2 diabetic patients. METHODS: A total of 172 type 2 diabetic patients (95 men...
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Management of Dyslipidemia according to the 2015 Treatment Guideline for Diabetes: Controversies and Issues to Resolve

Moon MK

The 2015 Treatment Guideline for Diabetes recommends statin therapy as the mainstay of management for dyslipidemia in order to lower low-density lipoprotein (LDL) cholesterol and thus prevent cardiovascular disease. It...
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Dyslipidemia Treatment in Diabetes Mellitus Patients

Kim SR

Cardiovascular disease (CVD) is the major cause of mortality and morbidity in patients with type 2 diabetes mellitus. The increased risk of CVD in subjects with type 2 diabetes mellitus...
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Cholesterol Lowering Effects of Low-dose Statins in Korean Patients

Kwon JE, Kim Y, Hyun S, Won H, Shin SY, Lee KJ, Kim SW, Kim TH, Kim CJ

OBJECTIVE: The aim of this study is to compare cholesterol lowering effects of low dose 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) in Korean patients. METHODS: A total of 909 consecutive patients...
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Cost-effectiveness of the Use of Statins in the Korean Population

Han KH, Kim HJ, Kim JJ

OBJECTIVE: Statins reduce risk of cardiovascular disease through lowering of LDL-C (Low Density Lipoprotein cholesterol). We analyzed cost-effectiveness of statins in the reduction of serum LDL-C level among Korean population...
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Effect of Omega-3 Fatty Acids on Low Density Lipoprotein Subfraction, Adiponectin and Apolipoprotein B in Type 2 Diabetic Patients

Jun H, Ko J, Jung H, Yoon C, Kim T, Kwon M, Lee S, Suk J, Kim M, Kim D, Park JH

BACKGROUND: Omega-3 fatty acids derived from fish oil have been reported to exert a beneficial effect on reducing cardiovascular disease. Reports about their mechanism have generated several interesting findings, including...
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LDL cholesterols levels after statin treatment: A comparison of measured vs. estimated values

Kim HJ, Suk JH, Kang JH, Kwon HY, Hwang CS, Kim MJ, Kim MK, Kim TI, Kim IJ

  • KMID: 2259097
  • Korean J Med.
  • 2010 Sep;79(3):277-284.
BACKGROUND/AIMS: Lowering low-density lipoprotein cholesterol (LDL-C) is the primary target for the prevention of cardiovascular disease. Previous studies have shown that estimated LDL-C levels calculated using Friedewald's formula (FLDL-C) are...
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The Relationships between UCP-1 Polymorphism and the Degree of Obesity or Plasma Lipid Profile in Prepubertal Children

Oh H, Shin E, Lee M

  • KMID: 2263216
  • Korean J Nutr.
  • 2008 Dec;41(8):767-775.
Uncoupling protein-1 (UCP-1) plays a major role in thermogenesis at brown adipose tissues and has been implicated in the pathogenesis of obesity and metabolic disorders. The purpose of this study...
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High Density Lipoprotein Cholesterol Comes of Age

Cho H

Despite the excellent success of lowering low-density lipoprotein cholesterol (LDLc) cholesterol for treating coronary heart disease (CHD), a major part of the population still suffer from CHD. This fact is...
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Concordance/Discordance between Apolipoprotein B Levels and the Cholesterol Indexes

Hwang ST, Kim BJ, Kim ER, Shin HS, Sung KC, Kim BS, Kang JH, Lee MH, Park JR, Ryu SH

BACKGROUND AND OBJECTIVES: Apolipoprotein B (Apo-B) has been reported to be a better predictor of the coronary artery disease (CAD) than the cholesterol indexes. The aim of this study was...
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Heritability and Segregation Analysis of the Level of LDL-Cholesterol

Jee SH, Yun JE, Nam CM, Suh I

BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the familial correlation and heritability of the LDL cholesterol level through a segregation analysis. SUBJECTS AND METHODS: This study...
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Danger of Hormone Replacement Therapy on Cardiovascular Disease

Cho HK

A myriad of the retrospective studies have shown the benefit of hormone replacement therapy (HRT) on cardiovascular disease. It has been consistently shown that estrogen decreases total and LDL cholesterol,...
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Comparison analysis of an indirect measurement of friedwal formula method and direct measurment of immunoseparation method on low-density lipoprotein cholesterol measurement

Kim GW, Cho BD, Lee HS, Jung SH, Oh KC, Yoon JU, Baek SH, Ryu KH, Rhim CY, Cho HC

  • KMID: 1984838
  • Korean J Med.
  • 2003 Jan;64(1):41-48.
BACKGROUND: In 2001, the third report the National Cholesterol Education Program (NCEP) has concluded that LDL cholesterol levels should be a major goal for preventing coronary artery disease and atherosclerotic...
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The effect of plant sterol on serum cholesterol in patients with hypercholesterolemia

Shin MJ, Rim SJ, Jang Y, Choi D, Kang SM, Cho SY, Kim SS, Kim D, Song K, Chung N

BACKGROUND AND OBJECT: Phytosterols(Plant sterols) have been known to reduce serum cholesterol concentrations by inhibiting absorption of both dietary and biliary cholesterol from the small intestines. However, the hypocholesterolemic effect...
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Cholesterol Lowering Therapy in Coronary Artery Disease: With Particular Reference to Statins

Jun JE

Statins (HMG-CoA reductase inhibitors) are widely used lipid lowering agents. They effectively reduce LDL cholesterol (LDL-C), lower triglyceride levels and are very safe. Recent large-scale clinical trials have demonstrated that...
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The relationship of smoking and alcohol consumption to blood pressure and lipid concentrations in male elderly living in Seoul, Korea

Choi KM, Kim KO, Cho YJ, Kim DR, Kim NH, Park IB, Baik SH, Choi DS

  • KMID: 2306131
  • Korean J Med.
  • 2001 Jun;60(6):521-528.
BACKGROUND: It is known that the effects of cigarette smoking and alcohol consumption on cardiovascular disease are very diverse. We investigated the effects of cigarette smoking and alcohol consumption on...
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