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MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells

Kang YJ, Kwon YH, Jang JY, Lee JH, Lee S, Park Y, Moon HR, Chung HY, Kim ND

Sirtuins (SIRTs) belong to the nicotinamide adenine dinucleotide (NAD+)-dependent class III histone deacetylase family. They are key regulators of cellular and physiological processes, such as cell survival, senescence, differentiation, DNA...
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Photocatalytic effect of doped-TiO 2 nanoparticles on discolored teeth

Shin U, Seol HJ, Kwon YH

The aim of this study was to determine the photocatalytic effect of doped-TiO 2 nanoparticles (NPs) on teeth bleaching with an aid of 3% H2O2 and laser irradiation. For the...
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Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis

Yu SJ, Lee HS, Gung HJ, Kim JS, Kim KB, Kwon YH, Kim JH, Koo HS, Shin HD, Jee SR, Lee HB, Kim J, Park HW, IBS Research Study Group of the Korean Society of Neurogastroenterology and Motility

Background/Aims: Dietary factors can aggravate the symptoms of irritable bowel syndrome (IBS). Many IBS patients try restrictive diets to relieve their symptoms, but the types of diets with an exacerbating...
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Intraocular Lens Scleral Fixation by Flanged Fixation Using 5-0 Polyprophylene

Choi SY, Kim NY, Kwon YH

Purpose: In patient with intraocular lens dislocation, surgery was performed to fix the existing intraocular lens to the sclera by flanged fixation using 5-0 polypropylene without replacing the existing intraocular...
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Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics

Cha RR, Kim JH, Koo HS, Jung KW, Min YW, Choi CH, Ryu HS, Kwon YH, Cho DH, Kwon JG, Park KS, Kim HJ

  • KMID: 2528043
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):283-290.
  • doi: 10.5056/jnm21108
Background/Aims Non-celiac gluten sensitivity is characterized by intestinal and extra intestinal symptoms associated with the consumption of gluten- containing food. Since biomarkers for non-celiac gluten sensitivity are lacking, its prevalence is estimated...
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Coring-out fistulectomy for perianal cryptoglandular fistula: a retrospective cohort study on 20 years of experience at a single center

Lee Ky, Lee J, Han EC, Kwon YH, Ryoo SB, Park KJ

Purpose: Cryptoglandular fistula is one of the common anal diseases requiring surgical treatment. Various surgical techniques have been introduced; however, there is no known standard technique. Coring-out fistulectomy is a...
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Effect of Sodium Alginate on Gastrointestinal Symptoms after Esophagogastroduodenoscopy with Biopsy: Randomized Controlled Trial

Nam SY, Lee SW, Jeon SW, Kwon YH

Background/Aims: After esophagogastroduodenoscopy (EGD) with biopsy, some patients experience gastrointestinal symptoms. This study investigated the effect of sodium alginate on biopsy-related gastrointestinal symptoms. Methods: In this open-label, randomized, controlled trial, patients...
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Effect of cooling rate during porcelain firing on the optical properties of 3 mol% yttria-stabilized zirconia

Shin HJ, Kwon YH, Seol HJ

This study investigated the effect of the difference in the cooling rates on the optical properties of zirconia during the simulated firing of porcelain, without a porcelain layer on a...
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Reliability of Goldberg Scoring System in the Radiographic Evaluation of Bony Union after Bone Grafting

Choi Y, Yang YH, Kwon YH

Background: Evaluation of bony union after bone grafting is very important in orthopedic surgery. The aim of this study was to verify inter- and intraobserver reliability of the Goldberg scoring...
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Case Report of a Pilot with Atopic Dermatitis

Kwon YH

Atopic dermatitis is a condition that makes skin red and itchy. It is common in children but can occur at any age. Atopic dermatitis is chronic and tends to flare...
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Comparative Observation of Body Mass Index among Adults in Korea and Japan

Lee MJ, Chae YH, Lee WC, Kwon YH

Background: Obesity is a major public health problem that is causally related to serious medical conditions. In this study, the public health implications of obesity based on body mass index (BMI)...
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COVID-19 Vaccination for Pilots and Air Traffic Controllers

Kwon YH

The coronavirus disease-19 (COVID-19) vaccine is expected to play an important role in stopping the pandemic. Studies show that COVID-19 vaccines are effective at keeping you from getting COVID-19. Getting...
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The Current Strategy of Helicobacter pylori Eradication

Kwon YH

Helicobacter pylori (H. pylori) is the main cause of most gastroduodenal diseases. Triple therapy including two antibiotics, amoxicillin and clarithromycin, and a proton pump inhibitor given for a week has...
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Temperature changes and compressive properties of bulk-fill composites by light curing

Yi Dh, Seol HJ, Kwon YH

The purpose of the present study was to assess the temperature change and compressive property of bulk-fill composites (BFCs) by the light curing. Seven resin-based composites (RBCs), including five BFCs,...
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The effect of cooling rate on hardness and microstructure of a metal-ceramic Au-Pt-Pd alloy during simulated firing

Jeong JI, Shin HJ, Kwon YH, Seol HJ

In this study, Au-Pt-Pd metal-ceramic alloy was examined by varying cooling rate during simulated porcelain firing cycles to investigate the effect of cooling rate on hardness and related microstructure during...
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Retroperitoneal sarcomas: Outcomes of repeated resections

Hwang H, Kwon YH, Lim HK, Kim J, Park KJ

Purpose: Retroperitoneal sarcomas (RPS) are rare malignant tumors arising from mesenchymal cells. The objective of this study was to review the treatment experiences and to identify prognostic factors for overall...
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COVID-19 and Aviation Medical Examination

Kwon YH

Coronavirus disease 2019 (COVID-19) has had a significant impact on our society as a whole. The COVID-19 pandemic is not only a health crisis, it is also an economic, social...
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Therapeutic Efficacy of Bone Marrow Derived Mesenchymal Stem Cells in Ototoxic Sensorineural Hearing Loss

Kim S, Kwon YH, Kim IB, Seo YJ, Han JS, Seo JH, Lee HJ, Park KH

Background and Objectives Ototoxic sensorineural hearing loss causes permanent hearing loss in most cases. Recently there have been many reports describing cell base therapy with stem cells that has some...
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Preoperative Colonoscopic Tattooing Using a Direct Injection Method with Indocyanine Green for Localization of Colorectal Tumors: An Efficacy and Safety Comparison Study

Kim YJ, Park JW, Lim HK, Kwon YH, Kim MJ, Choe EK, Moon SH, Ryoo SB, Jeong SY, Park KJ

Purpose: Endoscopic tattooing is used to mark colorectal lesions for subsequent surgery. As a tattooing agent, India ink has been widely used but is not currently available in Korea. Indocyanine...
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Impact of COVID-19 Pandemic on the National PPM Tuberculosis Control Project in Korea: the Korean PPM Monitoring Database between July 2019 and June 2020

Min Js, Kim HW, Koo HK, Ko Ys, Oh JY, Kim Jt, Yang Jy, Kwon Yh, Park YJ, Kang JY, Lee SS, Park JS, Kim JS

Background: The coronavirus disease 2019 (COVID-19) pandemic caused disruptions to healthcare systems and endangered the control and prevention of tuberculosis (TB). We investigated the nationwide effects of COVID-19 on the...
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