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Effect of Sonicated Extract of Treponema Denticola on Osteoclast Differentiation

Choi BK, Lee HJ, Jeong GJ, Jung SH, Kwak WA, Yoo YJ

Alveolar bone destruction is a characteristic of periodontal disease. Treponema denticola are found in significantly increased numbers in the sites affected with periodontal disease. In order to clarify the role...
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Effect of 17beta-Estradiol and 1,25-Dihydroxyvitamin D3 on Interleukin-6 Production of Periodontal Ligament Cells

Kwak WA, Choi BK, Lee HJ, Yoo YJ

  • KMID: 2321535
  • J Korean Acad Periodontol.
  • 1999 Sep;29(3):645-653.
Interleukin-6(IL-6) stimulate osteoclast differentiation. 17beta-estradiol, 1,25-dihydroxyvitamin D3(1,25-(OH)2D3) and interleukin-1beta inhibit or stimulate osteoclast differentiation by decreasing or increasing the synthesis of interleukin-6(IL-6) from stromal/osteoblastic cells, respectively. Periodontal ligament(PDL) cells reside...
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