- International regulatory considerations pertaining to the development of stem cell-based veterinary medicinal products
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Jeon BS, Yi H, Ku HO
- KMID: 2512436
- J Vet Sci.
- 2021 Jan;22(1):e6.
- doi: 10.4142/jvs.2021.22.e6
Stem cell-based products (SCPs) are an emerging field of veterinary medicine that focuses on the regeneration, repair, or replacement of damaged tissues or organs. However, there are some issues in... -
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- Guideline on safety evaluation of cell-based medicinal products for animal use
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Ku HO, Yi H, Park YI, Jeon BS, Kang HG, Kim YS, Park BK
- KMID: 2454016
- J Vet Sci.
- 2019 Mar;20(2):e14.
- doi: 10.4142/jvs.2019.20.e14
With the increased use of cell therapy in the veterinary sector, there is a growing demand for the development of cell-based medicinal products and the determination of their safety. Currently,... -
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- Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016
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Bang JH, Ku HO, Kang HG, Kim H, Kim S, Park SW, Kim YS, Jang I, Bae YC, Woo GH, Yi H
- KMID: 2454012
- J Vet Sci.
- 2019 Mar;20(2):e9.
- doi: 10.4142/jvs.2019.20.e9
Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity... -
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- Assessment of acute inhalation toxicity of citric acid and sodium hypochlorite in rats
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Kim J, Park CM, Choi SH, Yang MJ, Lee JY, Jeon BS, Ku HO, Kim MS
- KMID: 2541335
- J Vet Sci.
- 2023 Mar;24(2):e22.
- doi: 10.4142/jvs.22253
Background: Citric acid (CA) and sodium hypochlorite (NaOCl) have been used to disinfect animals to protect them against avian influenza and foot-and-mouth disease. Objectives: We performed a good laboratory practice (GLP)-compliant... -
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- High-content analysis of in vitro hepatocyte injury induced by various hepatotoxicants
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Tham NT, Hwang SR, Bang JH, Yi H, Park YI, Kang SJ, Kang HG, Kim YS, Ku HO
- KMID: 2434775
- J Vet Sci.
- 2019 Jan;20(1):34-42.
- doi: 10.4142/jvs.2019.20.1.34
In vitro prediction of hepatotoxicity can enhance the performance of non-clinical animal testing for identifying chemical hazards. In this study, we assessed high-content analysis (HCA) using multi-parameter cell-based assays as... -
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- Identification of urinary microRNA biomarkers for in vivo gentamicininduced nephrotoxicity models
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Jeon BS, Lee Sh, Hwang SR, Yi H, Bang JH, Tham NTT, Lee HK, Woo GH, Kang HG, Ku HO
- KMID: 2509150
- J Vet Sci.
- 2020 Nov;21(6):e81.
- doi: 10.4142/jvs.2020.21.e81
Background: Although previous in vivo studies explored urinary microRNA (miRNA), there is no agreement on nephrotoxicity-specific miRNA biomarkers. Objectives: In this study, we assessed whether urinary miRNAs could be employed as... -
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- Plasma haptoglobin and immunoglobulins as diagnostic indicators of deoxynivalenol intoxication
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Kim EJ, Jeong SH, Cho JH, Ku HO, Pyo HM, Kang HG, Choi KH
- KMID: 1718578
- J Vet Sci.
- 2008 Sep;9(3):257-266.
- doi: 10.4142/jvs.2008.9.3.257
This study aimed to discover potential biomarkers for dioxynivalenol (DON) intoxication. B6C3F1 male mice were rally exposed to 0.83, 2.5 and 7.5 mg/kg body weight (bw) DON for 8 days... -
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