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Education levels and survival in colorectal cancer: is there really an obvious association?

Valiati B, Perez RO, Kotze PG

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Endoscopic Postoperative Recurrence Rates in Crohn's Disease in Korea: The Beginning of a New Approach?

Kotze PG, Saad-Hossne R, Spinelli A

No abstract available.
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The old versus the new: which do you keep in postoperative Crohn's disease?

Kotze PG, Ma C, Regueiro M, Panaccione R

No abstract available.
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Preoperative use of anti-tumor necrosis factor therapy in Crohn's disease: promises and pitfalls

Kotze PG, Ghosh S, Bemelman W, Panaccione R

Recent advances in medical and surgical therapy were achieved during the last two decades in the management of Crohn's disease (CD). Anti-tumor necrosis factor (anti-TNF) agents are widely used worldwide....
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Conventional Versus Biological Therapy for Prevention of Postoperative Endoscopic Recurrence in Patients With Crohn's Disease: an International, Multicenter, and Observational Study

Kotze PG, Spinelli A, da Silva R, de Barcelos IF, Teixeira F, Saad-Hossne R, de Albuquerque IC, Olandoski , da Silva Kotze LM, Suzuki Y, Yamada A, Takeuchi K, Sacchi M, Yamamoto T

BACKGROUND/AIMS: Postoperative endoscopic recurrence (PER) occurs in nearly 80% of patients 1 year after ileocecal resection in patients with Crohn's disease (CD). Biological agents were more effective in reducing the...
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Biological Therapy for the Prevention and Treatment of Postoperative Endoscopic Recurrence in Crohn's Disease: Time for Acceptance?

Kotze PG, Saad-Hossne R

In most patients, postoperative endoscopic recurrence (PER) occurs 1 year after abdominal resection for Crohn's disease (CD). Preventing PER is essential for disease control, as most patients develop further clinical...
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Correlation of serum levels of anti-tumor necrosis factor agents with perianal fistula healing in Crohn’s disease: a narrative review

Miranda EF, Nones RB, Kotze PG

With the overspread use of measurement of serum levels of anti-tumor necrosis factor (TNF) agents (therapeutic drug monitoring, TDM), new therapeutic strategies have been used in the management of Crohn’s...
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Hypoalbuminemia as a risk factor for thromboembolic events in inflammatory bowel disease inpatients

Imbrizi MR, Magro DO, Secundo TD, Cunha-Silva M, Kotze PG, Montes CG, Almeida JR, Cabral VL

BACKGROUND/AIMS: Inflammatory bowel disease (IBD) are chronic entities characterized by local and systemic inflammation and may be associated with thrombosis. The aim of this study was to identify the prevalence...
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Comparison of time until elective intestinal resection regarding previous anti-tumor necrosis factor exposure: a Brazilian study on patients with Crohn's disease

Kotze PG, Magro DO, Saab B, Saab MP, Pinheiro L, Olandoski , Ayrizono M, Martinez C, Coy CS

BACKGROUND/AIMS: The use of anti-tumor necrosis factor (anti-TNF) agents seems to reduce surgical rates and delay surgical procedures in prospective trials and population-based studies in the management of Crohn's disease...
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Changes in serum levels of lipopolysaccharides and CD26 in patients with Crohn's disease

Magro DO, Kotze PG, Martinez C, Camargo MG, Guadagnini D, Calixto AR, Vasques AC, Ayrizono M, Geloneze B, Pareja JC, Saad MJ, Coy CS

BACKGROUND/AIMS: Lipopolysaccharide (LPS) is a molecule formed by lipids and polysaccharides and is the major cell wall component of gram-negative bacteria. High LPS levels are known to block CD26 expression...
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Consensus recommendations for patient-centered therapy in mild-to-moderate ulcerative colitis: the i Support Therapy–Access to Rapid Treatment (iSTART) approach

Danese S, Banerjee R, Cummings J, Dotan I, Kotze PG, Leong RW, Paridaens , Peyrin-Biroulet L, Scott G, Assche GV, Wehkamp J, Yamamoto-Furusho JK

Symptomatic ulcerative colitis (UC) can be a chronic, disabling condition. Flares in disease activity are associated with many of the negative impacts of mild-to-moderate UC. Rapid resolution of flares can...
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