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The influence of healthcare provider’s autonomy support, autonomous motivation and competence on self-care behaviors in kidney transplant patients based on self-determination theory

Son S, Ju Mk, Sim MK

Background: It is important for transplant patients to perform continuous self-care behavior after transplantation. The self-determination theory is that explains the persistence factors of health behavior of chronically ill patients....
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Mesenchymal stem cells enable delivery of an oncolytic adenovirus specifically to the tumor without posing any risk associated with systemic administration of naked virions to the host

Yoon A, Hong J, Yun CO

Background: Systemic delivery oncolytic virus to tumors remains a major challenge due to its poor tumor tropism and immunogenicity. Methods: In this regard, we hypothesize that mesenchymal stem cells (MSCs) with...
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Activation of transforming growth factor-β and epithelialmesenchymal transition enhance regulatory T cells-mediated metastasis

Yoon A, Hong J, Yun CO

Background: Even though substantial portion of patients with melanoma diagnosis are present with distant metastases, the un-derlying oncogenic process remains unclear.  Methods: We have hypothesized that regulatory T cells (Tregs) play...
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First experience of α1,3-galactosyltransferase gene-knockout (GTKO) transgenic pig to nonhuman primate lamellar corneal xenotransplantation

Yun IJ, Shin KC, Shin HS, Kim WS, Saindane M, Oh KB, Kang HJ, Ahn YR

Background: Corneal allotransplantation is a well-known technique to treat corneal blindness. However, the problem of organ scarcity in transplantology has become profound. One promising alternative could be xenograft using pig...
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Enhanced HLA typing performance of Korea Biobank Array with large scale reference panel

Kim SM, Jeong JC, Joo DJ, Yang J, Kim MS, Jang HM, Park HY, Kim BJ, Kim YJ

Background: In clinical transplantation, increased human leucocyte antigen (HLA) mismatch between donor and recipient were well-known risk factor for graft survival. However, HLA typing in a large scale genome study...
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Nine years experiences of solid organ xenotransplantation

Shin HS, Yun IJ, Chee HK, Kim JS, Park JH, Yang HS, Kim WS, Shin KC, Park KS, Oh KB

Background: There are far more patients awaiting transplantation than there are organ donors, the problem of organ scarcity has become more profound. One promising alternative could be xenograft using pig...
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Correlation of brain-dead organ donors’ age and time period between admission and the first brain death examination: 5 years data of Korea

Jeong Es, Tanim Anwar ASM, Lee Jm

Background: Deceased organ donation can be performed only with the consent of the donor or their family members. We tried to identify whether donor age is related to decision making...
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High success rate of liver and kidney transplant during seven months COVID-19 period

Karakaya E, Akdur A, Soy EA, Karakayali FY, Yildirim S, Torgay A, Sayin CB, Moray G, Haberal M

Background: During the pandemic, so many centers have postponed transplant surgery. In the present study, we aimed to evaluate our liver and kidney transplant during the pandemic period. Methods: During 7...
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Pancreas transplant in a young patient: an option

Zakria M

Background: Pancreas transplant is mainly offered to treat the insulin-dependent diabetes mellitus. In some cases, if there is loss of parenchyma due to trauma or chronic pancreatitis, total pancreatectomy is...
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Serial postoperative donor-derived cell-free DNA in recipients undergoing pancreas transplantation

Lee HJ, Choi BH, Shin KH, Kim IS, Kim HH

Background: Early detection of rejection after organ transplantation is important as it can prevent deterioration of the transplant- ed organ. With the development of molecular genetic technology, a digital PCR method that...
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How we achieved 0% of thrombotic graft loss: the initial 60 cases of pancreas transplant

Choi BH

Background: One of the major surgical complications after pancreas transplant is early graft failure due to thrombosis. Unfortunately, the early graft loss rate has not improved over the last 30...
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Outcome of ABO-incompatible kidney transplantation depending on the ABO type of transfused plasma: comparative analysis between the universal AB plasma and donor type plasma

Kim HJ, Kim JS, Yang JJ, Chung Y, Kim H, Shin S, Kim YH, Hwang SH, Oh HB, Ko DH

Background: Since the remarkable development of various desensitization methods and immunosuppressive agents, the outcome of ABO-incompatible solid organ transplantation has greatly improved. However, there is no evidence-based consensus about how...
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Development and validation of an algorithm to estimate eplet mismatch by substituting imputation of HLA antigens for highresolution HLA typing based on Korean HLA frequencies

Kim SK, Park BG, Son HE, Jeong JC, Hong YJ, Chae DW

Background: Assessment of eplet mismatches in transplantation requires high-resolution (HR) molecular human leukocyte antigen (HLA) typing. However, HR typing is rarely applied to solid organ transplantation. We developed an algorithm...
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Cellular immune monitoring for prediction of cytomegalovirus and BK viral reactivation after kidney transplantation

Shin KH, Lee JH, Song SH, Seong EY, Han M, Kim HH

Background: The reactivation of cytomegalovirus (CMV) and BK virus after kidney transplantation is a critical factor that affects donor and graft survival. However, accurate methods for viral reactivation prediction and...
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Causes of lowered family consent rate for organ donation

Yu E, Son Y, Han K, Lee M, Chong Y, Jeong Y, Lee J, Cho W

Background: The number of deceased donors that have increased annually until 2016 has started to decline in the last three years. This study therefore intends to analyze the trend of...
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Withdraw life sustaining treatment and organ donation

Jeong S, Hwang Y, Chu M, Yun O, Jeong Y, Lee J, Cho WH

Background: According to the statistics of the National Agency for Management of Life-Sustaining Treatment, 85,000 end of life care patients have been withdrawn life sustaining treatment over two years since...
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A narrative study on the life of organ procurement coordinator

Song HY, Cho HI, Cho W, Bok C

Background: Organ procurement coordinators (OPC) are the first person to approach the family when a potential brain death patient is referred and play a key role in attracting the donation...
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Single-institution analysis of willingness of waitlist patients to undergo kidney transplantation with expanded criteria brain-dead donors

Hong JJ, Lee SR, Lee AY, Woo JW, Park SB, Hwang S, Kim YH

Background: The waitlist period for kidney transplantation (KT) has been increasing due to intractable shortage of brain-dead donors in Korea. To solve this organ shortage issue, KT cases with expanded...
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Usefulness of preoperative magnetic resonance spectroscopy in improving the safety of a living liver donor

Shim JR, Ko HJ, Lee TB, Choi BH, Yang K, Ryu JH

Background: The steatosis of graft liver is an important factor in liver transplantation that determines the graft function in the recipient and the recovery of the remnant liver in the...
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Safety and efficacy of enhanced recovery after surgery (ERAS) program after donor hepatectomy: a propensity-matched analysis

Park SE, Choi HJ

Background: Enhanced recovery after surgery (ERAS) programs have been shown to have benefits for various surgery, and recently, several studies have reported the advantages of the ERAS program in liver...
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