- Curcumin Attenuates Glial Cell Activation But Cannot Suppress Hippocampal CA3 Neuronal Cell Death in i.c.v. Kanic Acid Injection Model
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Cho J, Kong PJ, Chun W, Moon YO, Park YT, Lim SY, Kim SS
- KMID: 1607514
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):307-310.
Kainic acid (KA) is a structural analogue of glutamate that interacts with specific presynaptic and postsynaptic receptors to potentiate the release and excitatory actions of glutamate. Systemic or intracerebroventricular (i.c.v.)... -
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- Neuroprotective Effects of Methanol Extracts of Jeju Native Plants on Hydrogen Peroxide-induced Cytotoxicity in SH-SY5Y Human Neuroblastoma Cells
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Kong PJ, Kim YM, Lee HJ, Kim SS, Yoo ES, Chun W
- KMID: 2285339
- Korean J Physiol Pharmacol.
- 2007 Oct;11(5):171-174.
Neuronal death is a common characteristic hallmark of a variety of neurodegenerative disorders including Alzheimer's disease and Parkinson's disease. However, there have been no effective drugs to successfully prevent neuronal... -
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- Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes
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Kong PJ, Byun JS, Lim SY, Lee JJ, Hong SJ, Kwon KJ, Kim SS
- KMID: 1486141
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):37-41.
- doi: 10.4196/kjpp.2008.12.2.37
Melatonin has been reported to protect neurons from a variety of neurotoxicity. However, the underlying mechanism by which melatonin exerts its neuroprotective property has not yet been clearly understood. We... -
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- Comparison of Inhibitory Potency of Various Antioxidants on the Activation of BV2 Microglial Cell Lines Induced by LPS
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Kong PJ, Park JI, Kwon OY, Han YH, Kim SY, Lee SN, Son HJ, Kim SS
- KMID: 1512912
- Korean J Physiol Pharmacol.
- 2007 Feb;11(1):9-13.
Antioxidant properties have been proposed as a mechanism for the putative anti-inflammatory effects of phenolic compounds. To reveal the relationship between antioxidant activity and anti-inflammatory effects of various antioxidants, we... -
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- Inhibition of eNOS/sGC/PKG Pathway Decreases Akt Phosphorylation Induced by Kainic Acid in Mouse Hippocampus
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Lee SH, Byun JS, Kong PJ, Lee HJ, Kim DK, Kim HS, Sohn JH, Lee JJ, Lim SY, Chun W, Kim SS
- KMID: 1457699
- Korean J Physiol Pharmacol.
- 2010 Feb;14(1):37-43.
- doi: 10.4196/kjpp.2010.14.1.37
The serine/threonine kinase Akt has been shown to play a role of multiple cellular signaling pathways and act as a transducer of many functions initiated by growth factor receptors that... -
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